IBT-UNAM : Dra. Rita Restano Cassulini | Dra. Rita Restano Cassulini
 Investigador en estancia postdoctoral Grupo del Dr. Lourival Domingos Possani Teléfonos Oficina +52 (777) 311-4900 ext 215
Laboratorio +52 (777) 329-1669
desde la CDMX 562-27669
red UNAM 27669
+52 (777) 311-4900 ext 215
|
Publicaciones recientes
Mourao,C.B.F. Brand,G.D. Fernandes,J.P.C. Prates,M.V. Bloch,C. Barbosa,J.A.R.G. Freitas,S.M. Restano-Cassulini,R. Possani,L.D. Schwartz,E.F.
2020. Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides Journal of Medicinal Chemistry, 63, 9500-9511.
Benard-Valle,M. Neri-Castro,E.E. Yanez-Mendoza,M.F. Lomonte,B. Olvera,A. Zamudio,F. Restano-Cassulini,R. Possani,L.D. Jimenez-Ferrer,E. Alagon,A.
2020. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom Journal of Proteomics, 225, 103863.
Gomez-Ramirez,I.V. Riano-Umbarila,L. Olamendi-Portugal,T. Restano-Cassulini,R. Possani,L.D. Becerril,B.
2020. Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico Toxicon, 184, 10-18.
Olamendi-Portugal,T. Batista,C.V.F. Pedraza-Escalona,M. Restano-Cassulini,R. Zamudio,F.Z. Benard-Valle,M. de Roodt,A.R. Possani,L.D.
2018. New insights into the proteomic characterization of the coral snake Micrurus pyrrhocryptus venom Toxicon, 153, 23-31.
Valdez-Velazquez,L.L. Olamendi-Portugal,T. Restano-Cassulini,R. Zamudio,F.Z. Possani,L.D.
2018. Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae) Journal of Venomous Animals and Toxins Including Tropical Diseases, 24, 17.
Guerrero-Garzon,J.F. Benard-Valle,M. Restano-Cassulini,R. Zamudio,F. Corzo,G. Alagon,A. Olvera-Rodriguez,A.
2018. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema Biochimie, 147, 114-121.
Batista,C.V.F. Martins,J.G. Restano-Cassulini,R. Coronas,F.I.V. Zamudio,F.Z. Procopio,R. Possani,L.D.
2018. Venom characterization of the Amazonian scorpion Tityus metuendus Toxicon, 143, 51-58.
Carcamo-Noriega,E.N. Olamendi-Portugal,T. Restano-Cassulini,R. Rowe,A. Uribe-Romero,S.J. Becerril,B. Possani,L.D.
2018. Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona Archives of Biochemistry and Biophysics, 638, 52-57.
Garcia-Garcia,F. Corrales-Garcia,L.L. Olamendi-Portugal,T. Restano-Cassulini,R. Vega,R. Vega,M. Ortiz,E. Sandoval-Lopez,G. Soto,E. Corzo,G.
2017. Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius Process Biochemistry, 62, 205-214.
Restano-Cassulini,R. Garcia,W. Paniagua-Solis,J.F. Possani,L.D.
2017. Antivenom Evaluation by Electrophysiological Analysis Toxins (Basel), 9, .
Olamendi-Portugal,T. Restano-Cassulini,R. Riano-Umbarila,L. Becerril,B. Possani,L.D.
2017. Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion centruroides limpidus Peptides, 87, 34-40.
Coronas,F.I. Diego-Garcia,E. Restano-Cassulini,R. de Roodt,A.R. Possani,L.D.
2015. Biochemical and physiological characterization of a new Na-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus Peptides, 68, 11-16.
Pedraza-Escalona,M. Batista,C.V. Restano-Cassulini,R. Sandoval-Rios,M. Coronas,F.I. Possani,L.D.
2014. A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells Journal of Proteomics, 111, 212-223.
Gonzalez-Morales,L. Pedraza-Escalona,M. Diego-Garcia,E. Restano-Cassulini,R. Batista,C.V. Gutierrez,M.C. Possani,L.D.
2014. Proteomic characterization of the venom and transcriptomic analysis of the venomous gland from the Mexican centipede Scolopendra viridis Journal of Proteomics, 111, 224-237.
Luna-Ramirez,K. Bartok,A. Restano-Cassulini,R. Quintero-Hernandez,V. Coronas,F. Christensen,J. Wright,C.E. Panyi,G. Possani,L.D.
2014. Structure, Molecular Modeling and Function of the First Potassium Channel Blocker, Urotoxin, Isolated from the Venom of the Australian Scorpion Urodacus Yaschenkoi Molecular Pharmacology, 86, 28-41.
Vergara,I. Pedraza-Escalona,M. Paniagua,D. Restano-Cassulini,R. Zamudio,F. Batista,C.V. Possani,L.D. Alagon,A.
2014. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A Journal of Proteomics, 105, 295-306.
Rodriguez-Ravelo,R. Restano-Cassulini,R. Zamudio,F.Z. Coronas,F.I.V. Espinosa-Lopez,G. Possani,L.D.
2014. A K+ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi Peptides, 53, 42-47.
Mourao,C.B. Heghinian,M.D. Barbosa,E.A. Mari,F. Bloch,C., Jr. Restano-Cassulini,R. Possani,L.D. Schwartz,E.F.
2013. Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment into the HWTX-II family Biochemistry, 52, 2440-2452.
Caliskan,F. Quintero-Hernandez,V. Restano-Cassulini,R. Coronas-Valderrama,F.I. Corzo,G. Possani,L.D.
2013. Molecular cloning and biochemical characterization of the first Na+-channel alpha-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom Biochimie, 95, 1216-1222.
Caliskan,F. Garcia,B.I. Coronas,F.I. Restano-Cassulini,R. Korkmaz,F. Sahin,Y. Corzo,G. Possani,L.D.
2012. Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda Peptides, 37, 106-112.
Jimenez-Vargas,J.M. Restano-Cassulini,R. Possani,L.D.
2012. Toxin modulators and blockers of hERG K(+) channels Toxicon, 60, 492-501.
Jimenez-Vargas,J.M. Restano-Cassulini,R. Possani,L.D.
2012. Interacting sites of scorpion toxin ErgTx1 with hERG1 K(+) channels Toxicon, 59, 633-641.
Caliskan,F. Quintero-Hernandez,V. Restano-Cassulini,R. Batista,C.V.F. Zamudio,F.Z. Coronas,F.I. Possani,L.D.
2012. Turkish scorpion Buthacus macrocentrus: General characterization of the venom and description of Bu1, a potent mammalian Na+-channel a-toxin Toxicon, 59, 408-415.
Camargos,T.S. Restano-Cassulini,R. Possani,L.D. Peigneur,S. Tytgat,J. Schwartz,C.A. de Freitas,S.M. Schwartz,E.F.
2011. The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum Peptides, 32, 1509-1517.
Garcia-Gomez,B.I. Coronas,F.I. Restano-Cassulini,R. Rodriguez,R.R. Possani,L.D.
2011. Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus Toxicon, 58, 18-27.
Estrada,G. Restano-Cassulini,R. Ortiz,E. Possani,L.D. Corzo,G.
2011. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6 Peptides, 32, 75-79 (Correction vol 32 p.1096).
Jimenez-Vargas,J.M. Restano-Cassulini,R. Quintero-Hernandez,V. Gurrola,G.B. Possani,L.D.
2011. Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function Peptides, 32, 560-567.
Redaelli,E. Restano-Cassulini,R. Fuentes-Silva,D. Clement,H. Schiavon,E. Zamudio,F.Z. Odell,G. Arcangeli,A. Clare,J.J. Alagon,A. Rodriguez de la Vega,R.C. Possani,L.D. Wanke,E.
2010. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels Journal of Biological Chemistry, 285, 4130-4142 (Correction vol 285 (17) pp 13314-13314).
Olamendi-Portugal,T. Batista,C.V. Restano-Cassulini,R. Pando,V. Villa-Hernandez,O. Zavaleta-Martinez-Vargas,A. Salas-Arruz,M.C. de la Vega RC Becerril,B. Possani,L.D.
2008. Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: Novel toxins, their function and phylogeny Proteomics, 8, 1919-1932.
Restano-Cassulini,R. Olamendi-Portugal,T. Zamudio,F. Becerril,B. Possani,L.D.
2008. Two Novel Ergtoxins, Blockers of K(+)-channels, Purified from the Mexican Scorpion Centruroides elegans elegans Neurochemical Research, 33, 1525-1533.
Wanke,E. Restano-Cassulini,R.
2007. Toxins interacting with ether-a-go-go-related gene voltage-dependent potassium channels Toxicon, 49, 239-248 * .
Lopez-Vera,E. Aguilar,M.B. Schiavon,E. Marinzi,C. Ortiz,E. Restano-Cassulini,R. Batista,C.V.F. Possani,L.D. Heimer de la Cotera,E.P. Peri,F. Becerril,B. Wanke,E.
2007. Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors Febs Journal, 274, 3972-3985.
Schiavon,E. Sacco,T. Restano-Cassulini,R. Gurrola,G. Tempia,F. Possani,L.D. Wanke,E.
2006. Resurgent current and voltage sensor-trapping enhanced activation by a {beta}-scorpion toxin solely in nav1.6 channel: Significance in Mice Purkinje Neurons Journal of Biological Chemistry, 281, 20326-20337.
Restano-Cassulini,R. Korolkova,Y.V. Diochot,S. Gurrola,G. Guasti,L. Possani,L. Lazdunski,M. Grishin,E. Arcangeli,A. Wanke,E.
2006. Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS Molecular Pharmacology, 69, 1673-1683.
Masi,A. Becchetti,A. Restano-Cassulini,R. Polvani,S. Hofmann,G. Buccoliero,A.M. Paglierani,M. Pollo,B. Taddei,G.L. Gallina,P. Di Lorenzo,N. Franceschetti,S. Wanke,E. Arcangeli,A.
2005. hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines British Journal of Cancer, 93, 781-792 * .
Orsini,F. Verotta,L. Lecchi,M. Restano-Cassulini,R. Curia,G. Redaelli,E. Wanke,E.
2004. Resveratrol Derivatives and Their Role as Potassium Channels Modulators Journal of Natural Products, 67, 421-426 * .
Pimpinelli,F. Redaelli,E. Restano-Cassulini,R. Curia,G. Giacobini,P. Cariboni,A. Wanke,E. Bondiolotti,G.P. Piva,F. Maggi,R.
2003. Depolarization differentially affects the secretory and migratory properties of two cell lines of immortalized luteinizing hormone-releasing hormone (LHRH) neurons European Journal of Neuroscience, 18, 1410-1418 * .
D'Amico,M. Biagiotti,T. Fontana,L. Restano-Cassulini,R. Lasagna,N. Arcangeli,A. Wanke,E. Olivotto,M.
2003. A HERG current sustains a cardiac-type action potential in neuroblastoma S cells Biochemical and Biophysical Research Communications, 302, 101-108 * .
Becchetti,A. De Fusco,M. Crociani,O. Cherubini,A. Restano-Cassulini,R. Lecchi,M. Masi,A. Arcangeli,A. Casari,G. Wanke,E.
2002. The functional properties of the human ether-+á-go-go-like (HELK2) K+ channel European Journal of Neuroscience, 16, 415-428 * .
Possani,L.D. Gurrola,G.B. Schwartz,E. Restano,R. 2011. Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano en: Paniagua Solis,J.F. Emergencias por Animales Ponzonosos en las Americas. Mexico. Instituto Bioclon. pags. 147-180
Rodriguez-de-la-Vega,R. Barraza,R. Restano,R. Possani,L.D. 2009. Toxins active on Herg channel: structure and function, en: de Lima,M.E. Animal toxins: State of the Art. Perspectives in Health and Biotechnology. Belo Horizonte. Universidad de Minas Gerais. pags. 193-204
* Indica publicación con otra institución de adscripción
