IBT-UNAM : Dr. Ricardo Alfredo Grande Cano
- Licenciatura: Biología, Fac. de Ciencias-UNAM (1996) - Maestría: en Biotecnología, IBt-UNAM (1995-1997)Ingreso directo al Doctorado sin titulacion
Premio Weizmann Kahn a la mejor tesis de doctorado en el área de Ciencias Naturales (2001)
Publicaciones recientes
Fajardo-Rebollar,E. Estrada,K. Grande,R. Ek Ramos,M.J. Ruiz-Vargas,G. Villegas-Torres,O.G. Juarez,A. Sanchez-Flores,A. Diaz-Camino,C.
2021. Bacterial and fungal microbiome profiling in chilhuacle negro chili (Capsicum annuum L.) associated with fruit rot disease Plant Disease, Jan 4 [Online ahead of print], .
Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez A. Garces-Ayala F. Gonzalez-Bonilla,C.R. Grajales-Muniz C. Borja-Aburto,V. Barrera-Badillo G. Lopez,S. Hernandez-Rivas L. Perez-Padilla,R. Lopez-Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F.
2020. Genomic Analysis of Early SARS-CoV-2 Variants Introduced in Mexico Journal of Virology, 94, .
Gonzalez,L.M. Estrada,K. Grande,R. Jimenez-Jacinto,V. Vega-Alvarado,L. Sevilla,E. Barrera,J. Cuesta,I. Zaballos,A. Bautista,J.M. Lobo,C.A. Sanchez-Flores,A. Montero,E.
2019. Comparative and functional genomics of the protozoan parasite Babesia divergens highlighting the invasion and egress processes PLoS Neglected Tropical Diseases, 13, e0007680.
Munoz-Medina,J.E. Garcia-Knight,M.A. Sanchez-Flores,A. Monroy-Munoz,I.E. Grande,R. Esbjornsson,J. Santacruz-Tinoco,C.E. Gonzalez-Bonilla,C.R.
2018.
Evolutionary analysis of the Chikungunya virus epidemic in Mexico reveals intra-host mutational hotspots in the E1 protein PLoS ONE, 13, e0209292.
Pena-Cardena,A. Grande,R. Sanchez,J. Tabashnik,B.E. Bravo,A. Soberon,M. Gomez,I.
2018. The C-terminal protoxin domain of Bacillus thuringiensis Cry1Ab toxin has a functional role in binding to GPI-anchored receptors in the insect midgut Journal of Biological Chemistry, 293, 20263-20272.
Gomez,I. Rodriguez-Chamorro,D.E. Flores-Ramirez,G. Grande,R. Zuniga,F. Portugal,F.J. Sanchez,J. Pacheco,S. Bravo,A. Soberon,M.
2018. Spodoptera frugiperda (J. E. Smith) aminopeptidase N1 is functional receptor of Bacillus thuringiensis Cry1Ca toxin Applied and Environmental Microbiology, 84, UNSP e01089-18.
Gomez-Angulo,J. Vega-Alvarado,L. Escalante-Garcia,Z. Grande,R. Gschaedler-Mathis,A. Amaya-Delgado,L. Arrizon,J. Sanchez-Flores,A.
2015. Genome Sequence of Torulaspora delbrueckii NRRL Y-50541, Isolated from Mezcal Fermentation Genome Announcements, 3, .
Vega-Alvarado,L. Gomez-Angulo,J. Escalante-Garcia,Z. Grande,R. Gschaedler-Mathis,A. Amaya-Delgado,L. Sanchez-Flores,A. Arrizon,J.
2015. High-Quality Draft Genome Sequence of Candida apicola NRRL Y-50540 Genome Announcements, 3, [correction en vol 3 (4) 2015].
Cuesta,I. Gonzalez,L.M. Estrada,K. Grande,R. Zaballos,A. Lobo,C.A. Barrera,J. Sanchez-Flores,A. Montero,E.
2014. High-Quality Draft Genome Sequence of Babesia divergens, the Etiological Agent of Cattle and Human Babesiosis Genome Announcements, 2, .
Gama-Castro,S. Salgado,H. Peralta-Gil,M. Santos-Zavaleta,A. Muniz-Rascado,L. Solano-Lira,H. Jimenez-Jacinto,V. Weiss,V. Garcia-Sotelo,J.S. Lopez-Fuentes,A. Porron-Sotelo,L. Alquicira-Hernandez,S. Medina-Rivera,A. Martinez-Flores,I. Alquicira-Hernandez,K. Martinez-Adame,R. Bonavides-Martinez,C. Miranda-Rios,J. Huerta,A.M. Mendoza-Vargas,A. Collado-Torres,L. Taboada,B. Vega-Alvarado,L. Olvera,M. Olvera,L. Grande,R. Morett,E. Collado-Vides,J.
2011. RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units) Nucleic Acids Research, 39, D98-D105.
Mendoza-Vargas,A. Olvera,L. Olvera,M. Grande,R. Vega-Alvarado,L. Taboada,B. Jimenez-Jacinto,V. Salgado,H. Juarez,K. Contreras-Moreira,B. Huerta,A.M. Collado-Vides,J. Morett,E.
2009. Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in E. coli PLoS ONE, 4, e7526.
Morett,E. Saab-Rincon,G. Olvera,L. Olvera,M. Flores,H. Grande,R.
2008. Sensitive Genome-Wide Screen for Low Secondary Enzymatic Activities: The YjbQ Family Shows Thiamin Phosphate Synthase Activity Journal of Molecular Biology, 376, 839-853.
Gomez,I. Arenas,I. Benitez,I. Miranda-Rios,J. Becerril,B. Grande,R. Almagro,J.C. Bravo,A. Soberon,M.
2006. Specific epitopes of domains II and IIII of bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in manduca sexta Journal of Biological Chemistry, 281, 34032-34039.
Gaytan,P. Yanez,J. Grande,R. Morett,E. Soberon,X.
2005. Improving random mutagenesis by purification of the oligonucleotide variants Combinatorial Chemistry & High Throughput Screening, 8, 537-544.
Chaney,M. Grande,R. Wigneshweraraj,S.R. Cannon,W. Casaz,P. Gallegos,M.T. Schumacher,J. Jones,S. Elderkin,S. Dago,A.E. Morett,E. Buck,M.
2001. Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action Genes and Development, 15, 2282-2294.
Grande,R.A. Valderrama,B. Morett,E.
1999. Suppression analysis of positive control mutants of NifA reveals two overlapping promoters for Klebsiella pneumoniae rpoN Journal of Molecular Biology, 294, 291-298.
Barrios,H. Grande,R. Olvera,L. Morett,E.
1998. In vivo genomic footprinting analysis reveals that the complex Bradyrhizobium japonicum fixRnifA promoter region is differently occupied by two distinct RNA polymerase holoenzymes Proceedings of the National Academy of Sciences of the United States of America, 95, 1014-1019.
Grande-Cano,R.A. Gomez I. 2015. Identification and characterization of receptors for insecticidal toxins from Bacillus thuringiensis en: Varma,A. Biocontrol of Lepidopteran Pests: Use of Soil Microbes and their Metabolites. Springer. pags. 71-88
Grande-Cano,R. Gomez,I. 2012. Protein expression and purification en: *isabelg Tools to Understand Protein-Protein Interactions. Kerala. Transworld Research Network. pags. 41-54
Gomez,I. Miranda-Rios,J. Arenas,I. Grande,R. Becerril,B. Bravo,A. Soberon,M. 2007. Identification of scFv Molecules that Recognize Loop 3 of Domain II and Domain III of Cry1Ab Toxin from Bacillus thuringiensis en: Vincent,C. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact,. Montreal. Erudit. pags. 12-14
Otras Publicaciones
Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes,P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado,E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez,A. Garces-Ayala,F. Gonzalez-Bonilla,C.R. Grajales-Muniz,C. Borja-Aburto,V.H. Barrera-Badillo,G. Lopez,S. Hernandez-Rivas,L. Perez-Padilla,R. Lopez Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F.
2020. Genomic analysis of early SARS-CoV-2 strains introduced in Mexico bioRxiv, Preprint posted May 30, 120402.
Grande-Cano,R.
2018. Secuenciación masiva de ADN Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 13, 13-21.