. Instituto de Biotecnologia UNAM

IBT-UNAM : M.B. Jose Raunel Tinoco Valencia

M.B. Jose Raunel Tinoco Valencia

Técnico Académico
Escalamiento y Planta Piloto

email: raunel @ibt.unam.mx

Publicaciones recientes

Riegas-Villalobos,A. Martinez-Morales,F. Tinoco-Valencia,R. Serrano-Carreon,L. Bertrand,B. Trejo-Hernandez,M.R. 2020. Efficient removal of azo-dye Orange II by fungal biomass absorption and laccase enzymatic treatment 3 Biotech, 10, 146.

Sanchez-Trasvina,C. Enriquez-Ochoa,D. Arellano-Gurrola,C. Tinoco-Valencia,R. Rito-Palomares,M. Serrano-Carreon,L. Mayolo-Deloisa,K. 2019. Strategies based on aqueous two-phase systems for the separation of laccase from protease produced by Pleurotus ostreatus Fluid Phase Equilibria, 502, 112281.

Cristiano-Fajardo,S.A. Flores,C. Flores,N. Tinoco-Valencia,R. Serrano-Carreon,L. Galindo,E. 2019. Glucose limitation and glucose uptake rate determines metabolite production and sporulation in high cell density continuous cultures of Bacillus amyloliquefaciens 83 Journal of Biotechnology, 299, 57-65.

Luna-Bulbarela,A. Tinoco-Valencia,R. Corzo,G. Kazuma,K. Konno,K. Galindo,E. Serrano-Carreon,L. 2018. Effects of bacillomycin D homologues produced by Bacillus amyloliquefaciens 83 on growth and viability of Colletotrichum gloeosporioides at different physiological stages Biological Control, 127, 145-154.

Rosas-Galvan,N.S. Martinez-Morales,F. Marquina-Bahena,S. Tinoco-Valencia,R. Serrano-Carreon,L. Bertrand,B. Leon-Rodriguez,R. Guzman-Aparicio,J. Alvarez-Berber,L. Trejo-Hernandez,M.D.R. 2018. Improved production, purification and characterization of biosurfactants produced by Serratia marcescens SM3 and its isogenic SMRG-5 strain Biotechnology and Applied Biochemistry, 85, 690-700.

Adaya,L. Millan,M. Pena,C. Jendrossek,D. Espin,G. Tinoco-Valencia,R. Guzman,J. Pfeiffer,D. Segura,D. 2018. Inactivation of an intracellular poly-3-hydroxybutyrate depolymerase of Azotobacter vinelandii allows to obtain a polymer of uniform high molecular mass Applied Microbiology and Biotechnology, 102, 2693-2707.

Fernandez-Lopez,M.G. Popoca-Ursino,C. Sanchez-Salinas,E. Tinoco-Valencia,R. Folch-Mallol,J.L. Dantan-Gonzalez,E. Ortiz-Hernandez,M.L. 2017. Enhancing methyl parathion degradation by the immobilization of Burkholderia sp. isolated from agricultural soils Microbiologyopen, 6, e00507.

Bertrand,B. Mayolo-Deloisa,K. Gonzalez-Gonzalez,M. Tinoco-Valencia,R. Serrano-Carreon,L. Martinez-Morales,F. Trejo-Hernandez,M.R. Rito-Palomares,M. 2016. Pleurotus ostreatus laccase recovery from residual compost using aqueous two-phase systems Journal of Chemical Technology and Biotechnology, 91, 2235-2242.

Fernandez-Alejandre,K.I. Flores,N. Tinoco-Valencia,R. Caro,M. Flores,C. Galindo,E. Serrano-Carreon,L. 2016. Diffusional and transcriptional mechanisms involved in laccases production by Pleurotus ostreatus CP50 Journal of Biotechnology, 223, 42-49.

Bertrand,B. Martinez-Morales,F. Tinoco-Valencia,R. Rojas,S. Acosta-Urdapilleta,L. Trejo-Hernandez,M.R. 2015. Biochemical and molecular characterization of laccase isoforms produced by the white-rot fungus Trametes versicolor under submerged culture conditions Journal of Molecular Catalysis B: Enzymatic, 122, 339-347.

Dantan-Gonzalez,E. Quiroz-Castaneda,R.E. Cobaxin-Cardenas,M. Valle-Hernandez,J. Gama-Martinez,Y. Tinoco-Valencia,J.R. Serrano-Carreon,L. Ortiz-Hernandez,L. 2015. Impact of Meyerozyma guilliermondii isolated from chickens against Eimeria sp. protozoan, an in vitro analysis BMC Veterinary Research, 11, 278.

Gasteazoro,F. Simaan,A.J. Tinoco-Valencia,R. Valderrama,B. 2015. Validation of a General Method for Activity Estimation of Cyanide Evolving Oxidoreductases Analytical Biochemistry, 471, 44-50.

Martinez-Morales,F. Bertrand,B. Pasion Nava,A.A. Tinoco,R. Acosta-Urdapilleta,L. Trejo-Hernandez,M.R. 2015. Production, purification and biochemical characterization of two laccase isoforms produced by Trametes versicolor grown on oak sawdust Biotechnology Letters, 37, 391-396.

Duran,E.A. Tinoco,R. Perez,A. Berrones,R. Eapen,D. Sebastian,P.J. 2014. A Conparative Study of Biodiesel Purification with Magnesium Silicate and Water Journal of New Materials for Electrochemical Systems, 17, 105-111.

Duran-Padilla,V.R. Davila-Vazquez,G. Chavez-Vela,N.A. Tinoco-Valencia,R. Jauregui-Rincon,J. 2014. Iron effect on the fermentative metabolism of Clostridium acetobutylicum ATCC 824 using cheese whey as substrate Biofuel Research Journal, 5, 129-133.

Duran,E.A. Tinoco,R. Perez,A. Berrones,R. Eapen,D. Sebastian,P.J. 2014. A Comparative Study of Biodiesel Purification with Magnesium Silicate and Water Journal of New Materials for Electrochemical Systems, 17, 105-111.

Morales-Sanchez,D. Tinoco-Valencia,R. Caro-Bermudez,M.A. Martinez,A. 2014. Culturing Neochloris oleoabundans microalga in a nitrogen-limited, heterotrophic fed-batch system to enhance lipid and carbohydrate accumulation Algal Research, 5, 61-69.

Tinoco-Valencia,R. Gomez-Cruz,C. Galindo,E. Serrano-Carreon,L. 2014. Toward an understanding of the effects of agitation and aeration on growth and laccases production by Pleurotus ostreatus Journal of Biotechnology, 177, 67-73.

Bertrand,B. Martinez-Morales,F. Tinoco,R. Rojas-Trejo,S. Serrano-Carreon,L. Trejo-Hernandez,M.R. 2014. Induction of laccases in Trametes versicolor by aqueous wood extracts World Journal Of Microbiology & Biotechnology, 30, 135-142.

Gutierrez-Roman,M.I. Dunn,M.F. Tinoco-Valencia,R. Holguin-Melendez,F. Huerta-Palacios,G. Guillen-Navarro,K. 2014. Potentiation of the synergistic activities of chitinases ChiA, ChiB and ChiC from Serratia marcescens CFFSUR-B2 by chitobiase (Chb) and chitin binding protein (CBP) World Journal Of Microbiology & Biotechnology, 30, 33-42.

Morales-Sanchez,D. Tinoco-Valencia,R. Kyndt,J. Martinez,A. 2013. Heterotrophic growth of Neochloris oleoabundans using glucose as a carbon source Biotechnology for Biofuels, 6, 100.

Tenorio-Salgado,S. Tinoco,R. Vazquez-Duhalt,R. Caballero-Mellado,J. Perez-Rueda,E. 2013. Identification of volatile compounds produced by the bacterium Burkholderia tropica that inhibit the growth of fungal pathogens Bioengineered, 4, .

Chino-Flores,C. Dantan-Gonzalez,E. Vazquez-Ramos,A. Tinoco-Valencia,R. Diaz-Mendez,R. Sanchez-Salinas,E. Castrejon-Godinez,M.L. Ramos-Quintana,F. Ortiz-Hernandez,Ma.L. 2012. Isolation of the opdE gene that encodes for a new hydrolase of Enterobacter sp. capable of degrading organophosphorus pesticides Biodegradation, 23, 387-397.

Tinoco,R. Acevedo,A. Galindo,E. Serrano-Carreon,L. 2011. Increasing Pleurotus ostreatus laccase production by culture medium optimization and copper/lignin synergistic induction Journal of Industrial Microbiology & Biotechnology, 38, 531-540.

Torres-Duarte,C. Roman,R. Tinoco,R. Vazquez-Duhalt,R. 2009. Halogenated pesticide transformation by a laccase-mediator system Chemosphere, 77, 687-692.

Rosas,A. Vazquez-Duhalt,R. Tinoco,R. Shimada,A. Dabramo,L.R. Viana,M.T. 2008. Comparative intestinal absorption of amino acids in rainbow trout (Oncorhynchus mykiss), totoaba (Totoaba macdonaldi) and Pacific bluefin tuna (Thunnus orientalis) Aquaculture Nutrition, 14, 481-489.

Quintanilla-Guerrero,F. Duarte-Vazquez,M.A. Tinoco,R. Gomez-Suarez,M. Garcia-Almendarez,B.E. Vazquez-Duhalt,R. Regalado,C. 2008. Chemical Modification of Turnip Peroxidase with Methoxypolyethylene Glycol Enhances Activity and Stability for Phenol Removal Using the Immobilized Enzyme Journal of Agricultural and Food Chemistry, 56, 8058-8065.

Aguila,S. Vazquez-Duhalt,R. Tinoco,R. Rivera,M. Pecchi,G. Alderete,J.B. 2008. Stereoselective oxidation of R-(+)-limonene by chloroperoxidase from Caldariomyces fumago Green Chemistry, 10, 647-653.

Quintanilla-Guerrero,F. Duarte-Vazquez,M.A. Garcia-Almendarez,B.E. Tinoco,R. Vazquez-Duhalt,R. Regalado,C. 2008. Polyethylene glycol improves phenol removal by immobilized turnip peroxidase Bioresource Technology, 99, 8605-8611.

Longoria,A. Tinoco,R. Vazquez-Duhalt,R. 2008. Chloroperoxidase-mediated transformation of highly halogenated monoaromatic compounds Chemosphere, 72, 485-490.

Tinoco,R. Verdin,J. Vazquez-Duhalt,R. 2007. Role of oxidizing mediators and tryptophan 172 in the decoloration of industrial dyes by the versatile peroxidase from Bjerkandera adusta Journal Of Molecular Catalysis B-Enzymatic, 46, 1-7.

Cabrera-Valladares,N. Martinez,A. Pinero,S. Lagunas-Munoz,V.H. Tinoco,R. de Anda,R. Vazquez-Duhalt,R. Bolivar,F. Gosset,G. 2006. Expression of the melA gene from Rhizobium etli CFN42 in Escherichia coli and characterization of the encoded tyrosinase Enzyme and Microbial Technology, 38, 772-779.

Davila-Vazquez,G. Tinoco,R. Pickard,M.A. Vazquez-Duhalt,R. 2005. Transformation of halogenated pesticides by versatile peroxidase from Bjerkandera adusta Enzyme and Microbial Technology, 36, 223-231.

Vandertol-Vanier,H.A. Vazquez-Duhalt,R. Tinoco,R. Pickard,M.A. 2002. Enhanced activity by poly(ethylene glycol) modification of Coriolopsis gallica laccase Journal of Industrial Microbiology & Biotechnology, 29, 214-220.

Barajas-Aceves,M. Hassan,M. Tinoco,R. Vazquez-Duhalt,R. 2002. Effect of pollutants on the ergosterol content as indicator of fungal biomass Journal of Microbiological Methods, 50, 227-236.

Vazquez-Duhalt,R. Tinoco,R. D'Antonio,P. Topoleski,L.D. Payne,G.F. 2001. Enzyme conjugation to the polysaccharide chitosan: smart biocatalysts and biocatalytic hydrogels Bioconjugate Chemistry, 12, 301-306.

Tinoco,R. Pickard,M.A. Vazquez-Duhalt,R. 2001. Kinetic differences of purified laccases from six Pleurotus ostreatus strains Letters in Applied Microbiology, 32, 331-335.

Busi,E. Howes,B.D. Pogni,R. Basosi,R. Tinoco,R. Vazquez-Duhalt,R. 2000. Modified cytochrome c/H2O2 system: spectroscopic EPR investigation of the biocatalytic behaviour Journal Of Molecular Catalysis B-Enzymatic, 9, 39-48.

Pickard,M.A. Roman,R. Tinoco,R. Vazquez-Duhalt,R. 1999. Polycyclic aromatic hydrocarbon metabolism by white rot fungi and oxidation by Coriolopsis gallica UAMH 8260 laccase Applied and Environmental Microbiology, 65, 3805-3809.

Tinoco,R. Vazquez-Duhalt,R. 1998. Chemical modification of cytochrome C improves their catalytic properties in oxidation of polycyclic aromatic hydrocarbons Enzyme and Microbial Technology, 22, 8-12.

Ayala,M. Tinoco,R. Hernandez,V. Bremauntz,P. Vazquez-Duhalt,R. 1998. Biocatalytic oxidation of fuel as an alternative to biodesulfurization Fuel Processing Technology, 57, 101-111.

Torres,E. Tinoco,R. Vazquez-Duhalt,R. 1997. Biocatalytic oxidation of polycyclic aromatic hydrocarbons in media containing organic solvents Water Science and Technology, 36, 37-44.

Tinoco,R. Hernandez-Saavedra,D. Ochoa,J.L. Vazquez-Duhalt,R. 1996. Biochemical method for chlorine dioxide determination Analytical Biochemistry, 241, 18-22.

Torres,E. Tinoco,R. Vazquez-Duhalt,R. 1996. Solvent hydrophobicity predicts biocatalytic behaviour of lignin peroxidase and cytochrome c in aqueous solution of water-miscible organic solvents Journal of Biotechnology, 49, 59-67.

Longoria,A. Tinoco,R. Torres,E. 2010. Enzyme technology of peroxidases. Immobilization, chemical and genetic modification en: *maa Biocatalysis based on heme peroxidases . Peroxidases as Potential Industrial Biocatalysts. Springer. pags. 209-244

Tinoco-Valencia,R. Vazquez-Duhalt,R. 2008. Biocatálisis ambiental en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 30. Mexico, D.F.. UNAM. pags. 347-360

Jauregui-Rincon,J. Araiza,G.J.A. Aguila,M. Tinoco,R.V. 2005. Mycoremediation of soil contaminated with hydrocarbons en: Kelly.M.E. Proceedings of the 8th International In Situ and On-Site Bioremediation Symposium. Columbus, OH. Battelle Press. pags. 428-433

VazquezDuhalt,R. Torres,E. Tinoco,R. 1997. 2 en: In Situ and On-Site Bioremediation, Vol 2. Columbus, OH. Batelle Press. pags. 225-230

Otras Publicaciones

Longoria,A. Hu,H. Tinoco-Valencia,R. Vazquez-Duhalt,R. 2008. Síntesis enzimática de polímeros semiconductores utilizando la cloroperoxidasa de Caldariomyces fumago TIP revista especializada en Ciencias Quimico-Biologicas, 11, 73-80.

Patentes

R. Vázquez-Duhalt, J. R. Tinoco, D. Hernández y J.L. Ochoa 2005 Método bioquímico específico para la determinación de dióxido de cloro.UNAM y CIBNOR México.

R. Vázquez-Duhalt, M. P. Bremauntz y J. R. Tinoco 2002 Enzymatic oxidation process for desulfuration of fossil fuels.UNAM e IMP Estados Unidos.

R. V·zquez D. M. P. Bremauntz E. B·rzana J. R. Tinoco 1999 Enzymatic oxidation process for desulfurization of fossil fuels.UNAM-IMP Estados Unidos.

R. V·zquez D. J.R. Tinoco V. D. Hern·ndez S. J.L. Ochoa O. 1997 Método bioquímico específico para la determinación de dióxido de cloro.UNAM-CIBNOR México. (en trámite)