IBT-UNAM : Dr. Pavel Isa
Dr. Pavel Isa
Grupo del Dr. Carlos Federico Arias
Teléfonos
Oficina +52 (777) 311-4900 ext 239 Laboratorio +52 (777) 329-1612 red UNAM 27612 +52 (777) 311-4900 ext 239
- Licenciatura: Medico Veterinario, Universidad Veterinaria de Brno, Checoslovaquia, Fac. General de Medicina Veterinaria (1987)
Premio Bienal Funsalud en Enfermedades Gastrointestinales (NADRO) Fundación Mexicana para la Salud (2002)
Estudiantes M.C. Arianna Perez
M.C. Carlos Enrique Baez
Publicaciones recientes
Aguado-Garcia,Y. Taboada,B. Moran,P. Rivera-Gutierrez,X. Serrano-Vazquez,A. Isa,P. Rojas-Velazquez,L. Perez-Juarez,H. Lopez,S. Torres,J. Ximenez,C. Arias,C.F.
2020. Tobamoviruses can be frequently present in the oropharynx and gut of infants during their first year of life Scientific Reports, 10, 13595.
Isa,P. Perez-Delgado,A. Quevedo,I.R. Lopez,S. Arias,C.F.
2020. Rotaviruses Associate with Distinct Types of Extracellular Vesicles Viruses, 12, 763.
Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez A. Garces-Ayala F. Gonzalez-Bonilla,C.R. Grajales-Muniz C. Borja-Aburto,V. Barrera-Badillo G. Lopez,S. Hernandez-Rivas L. Perez-Padilla,R. Lopez-Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F.
2020. Genomic Analysis of Early SARS-CoV-2 Variants Introduced in Mexico Journal of Virology, 94, .
Taboada,B. Isa,P. Gutierrez-Escolano,A.L. del Angel,R.M. Ludert,J.E. Vazquez,N. Tapia-Palacios,M.A. Chavez,P. Garrido,E. Espinosa,A.C. Eguiarte,L.E. Lopez,S. Souza,V. Arias,C.F.
2018. The Geographic Structure of Viruses in the Cuatro Ciénegas Basin, a Unique Oasis in Northern Mexico, Reveals a Highly Diverse Population on a Small Geographic Scale Applied and Environmental Microbiology, 84, e00465-18.
Velazquez-Salinas,L. Isa,P. Pauszek,S.J. Rodriguez,L.L.
2017. Complete Genome Sequences of Two Vesicular Stomatitis Virus Isolates Collected in Mexico Genome Announcements, 5, .
Taboada,B.T. Isa,P. Espinoza,M.A. Aponte,F.E. Arias-Ortiz,M.A. Monge-Martinez,J. Rodriguez-Vazquez,R. Diaz-Hernandez,F. Zarate-Vidal,F. Wong-Chew,R.M. Firo-Reyes,V. Del Rio-Almendarez,C.N. Gaitan-Meza,J. Villasenor-Sierra,A. Martinez-Aguilar,G. Garcia-Borjas,M. Noyola,D.E. Perez-Gonzalez,L.F. Lopez,S. Santos-Preciado,J.I. Arias,C.F.
2016. Complete Genome Sequence of Human Coronavirus OC43 Isolated from Mexico Genome Announcements, 4, .
Cevallos-Porta D. Lopez,S. Arias,C.F. Isa,P.
2016. Polarized rotavirus entry and release from differentiated small intestinal cells Virology, 499, 65-71.
Garcia-Chequer,A.J. Mendez-Tenorio,A. Olguin-Lopez,G. Sanchez-Vallejo,C. Isa,P. Arias,C.F. Torres,J. Hernandez-Angeles,A. Ramirez-Ortiz,M.A. Lara,C. Cabrera-Munoz,M. Sadowinski-Pine,S. Bravo-Ortiz,J.C. Ramon-Garcia,G. Diegoperez-Ramirez,J. Ramirez-Reyes,G. Casarrubias-Islas,R. Ramirez,J. Orjuela,M. Ponce-Castaneda,M.V.
2016. Illumina next generation sequencing data and expression microarrays data from retinoblastoma and medulloblastoma tissues Data in Brief, 6, 908-916.
Garcia-Chequer,A.J. Mendez-Tenorio,A. Olguin-Ruiz,G. Sanchez-Vallejo,C. Isa,P. Arias,C.F. Torres,J. Hernandez-Angeles,A. Ramirez-Ortiz,M.A. Lara,C. Cabrera-Munoz,M.L. Sadowinski-Pine,S. Bravo-Ortiz,J.C. Ramon-Garcia,G. Diegoperez-Ramirez,J. Ramirez-Reyes,G. Casarrubias-Islas,R. Ramirez,J. Orjuela,M.A. Ponce-Castaneda,M.V.
2016. Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing Cancer Genetics, 209, 57-69.
Martinez,M.A. Soto-Del Rio,M.D. Gutierrez,R.M. Greninger,A.L. Contreras,J.F. Lopez,S. Arias,C.F. Isa,P.
2015. DNA microarray for detection of gastrointestinal viruses Journal of Clinical Microbiology, 53, 136-145.
Taboada,B. Espinoza,M.A. Isa,P. Aponte,F.E. Arias-Ortiz,M.A. Monge-Martinez,J. Rodriguez-Vazquez,R. Diaz-Hernandez,F. Zarate-Vidal,F. Wong-Chew,R.M. Firo-Reyes,V. Del Rio-Almendarez,C.N. Gaitan-Meza,J. Villasenor-Sierra,A. Martinez-Aguilar,G. Salas-Mier,M.D. Noyola,D.E. Perez-Gonzalez,L.F. Lopez,S. Santos-Preciado,J.I. Arias,C.F.
2014. Is There Still Room for Novel Viral Pathogens in Pediatric Respiratory Tract Infections? PLoS ONE, 9, e113570.
Escalera-Zamudio,M. Nelson,M.I. Cobian-Guemes,A.G. Lopez-Martinez,I. Cruz-Ortiz,N. Iguala-Vidales,M. Garcia,E.R. Barrera-Badillo,G. Diaz-Quinonez,J.A. Lopez,S. Arias,C.F. Isa,P.
2014. Molecular Epidemiology of Influenza A/H3N2 Viruses Circulating in Mexico from 2003 to 2012 PLoS ONE, 9, e102453.
Naccache,S.N. Federman,S. Veeeraraghavan,N. Zaharia,M. Lee,D. Samayoa,E. Bouquet,J. Greninger,A.L. Luk,K.C. Enge,B. Wadford,D.A. Messenger,S.L. Genrich,G.L. Pellegrino,K. Grard,G. Leroy,E. Schneider,B.S. Fair,J.N. Martinez,M.A. Isa,P. Crump,J.A. Derisi,J.L. Sittler,T. Hackett,J. Miller,S. Chiu,C.Y.
2014. A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples Genome Research, 24, 1180-1192.
Paulin,L.F. Soto-Del Rio,M.D. Sanchez,I. Hernandez,J. Gutierrez-Rios,R.M. Lopez-Martinez,I. Wong-Chew,R.M. Parissi-Crivelli,A. Isa,P. Lopez,S. Arias,C.F.
2014. PhyloFlu, a DNA microarray to determine the phylogenetic origin of influenza A gene segments and the genomic fingerprint of viral strains Journal of Clinical Microbiology, 52, 803-813.
Vazquez-Perez,J.A. Isa,P. Kobasa,D. Ormsby,C.E. Ramirez-Gonzalez,J.E. Romero-Rodriguez,D.P. Ranadheera,C. Li,Y. Bastien,N. Embury-Hyatt,C. Gonzalez-Duran,E. Barrera-Badillo,G. Ablanedo-Terrazas,Y. Sevilla-Reyes,E.E. Escalera-Zamudio,M. Cobian-Guemes,A.G. Lopez,I. Ortiz-Alcantara,J. Alpuche-Aranda,C. Perez-Padilla,J.R. Reyes-Teran,G.
2013. A (H1N1) pdm09 HA D222 variants associated with severity and mortality in patients during a second wave in Mexico Virology Journal, 10, 41-p.
Martinez,M.A. Lopez,S. Arias,C.F. Isa,P.
2013. Gangliosides have a functional role during rotavirus cell entry Journal of Virology, 87, 1115-1122.
Yu,G. Greninger,A.L. Isa,P. Phan,T.G. Martinez,M.A. de la Luz,S.M. Contreras,J.F. Santos-Preciado,J.I. Parsonnet,J. Miller,S. Derisi,J.L. Delwart,E. Arias,C.F. Chiu,C.Y.
2012. Discovery of a novel polyomavirus in acute diarrheal samples from children PLoS ONE, 7, e49449.
Escalera-Zamudio,M. Cobian-Guemes,G. Soto-Del Rio,M.D. Isa,P. Sanchez-Betancourt,I. Parissi-Crivelli,A. Martinez-Cazares,M.T. Romero,P. Velazquez-Salinas,L. Huerta-Lozano,B. Nelson,M. Montero,H. Vinuesa,P. Lopez,S. Arias,C.F.
2012. Characterization of an influenza A virus in Mexican swine that is related to the A/H1N1/2009 pandemic clade Virology, 433, 176-182.
Carreno-Torres,J.J. Gutierrez,M. Arias,C.F. Lopez,S. Isa,P.
2010. Characterization of viroplasm formation during the early stages of rotavirus infection Virology Journal, 7, 350-355.
Greninger,A.L. Chen,E.C. Sittler,T. Scheinerman,A. Roubinian,N. Yu,G. Kim,E. Pillai,D.R. Guyard,C. Mazzulli,T. Isa,P. Arias,C.F. Hackett,J. Schochetman,G. Miller,S. Tang,P. Chiu,C.Y.
2010. A Metagenomic Analysis of Pandemic Influenza A (2009 H1N1) Infection in Patients from North America PLoS ONE, 5, e13381.
Gutierrez,M. Isa,P. Sanchez-SanMartin,C. Perez-Vargas,J. Espinosa,R. Arias,C.F. Lopez,S.
2010. Different rotavirus strains enter MA104 cells through different endocytic pathways: The role of clathrin-mediated endocytosis Journal of Virology, 84, 9161-9169.
Arias,C.F. Escalera-Zamudio,M. Soto-Del Rio,M.D. Cobian-Guemes,A.G. Isa,P. Lopez,S.
2009. Molecular Anatomy of 2009 Influenza Virus A (H1N1) Archives of Medical Research, 40, 643-654.
Isa,P. Sanchez-Aleman,M.A. Lopez,S. Arias,C.F.
2009. Dissecting the role of integrin subunits alpha2 and beta3 in rotavirus cell entry by RNA silencing Virus Research, 145, 251-259.
Isa,P. Gutierrez,M. Arias,C.F. Lopez,S.
2008. Rotavirus cell entry Future Virology, 3, 135-146.
Isa,P. Arias,C.F. Lopez,S.
2006. Role of sialic acids in rotavirus infection Glycoconjugate Journal, 23, 27-37.
Perez-Vargas,J. Isa,P. Lopez,S. Arias,C.F.
2006. Rotavirus vaccine: early introduction in Latin America-risks and benefits Archives of Medical Research, 37, 1-10.
Arias,C.F. Dector,M.A. Segovia,L. Lopez,T. Camacho,M. Isa,P. Espinosa,R. Lopez,S.
2004. RNA silencing of rotavirus gene expression Virus Research, 102, 43-51.
Isa,P. Realpe,M. Romero,P. Lopez,S. Arias,C.F.
2004. Rotavirus RRV associates with lipid membrane microdomains during cell entry Virology, 322, 370-381 [Correction vol 328 p 158].
Arias,C.F. Isa,P. Guerrero,C. Mendez,E. Zarate,S. Lopez,T. Espinosa,R. Romero,P. Lopez,S.
2002. Molecular biology of rotavirus cell entry Archives of Medical Research, 33, 356-361.
Pando,V. Isa,P. Arias,C.F. Lopez,S.
2002. Influence of calcium on the early steps of rotavirus infection Virology, 295, 190-200.
Guerrero,C.A. Bouyssounade,D. Zarate,S. Isa,P. Lopez,T. Espinosa,R. Romero,P. Mendez,E. Lopez,S. Arias,C.F.
2002. Heat shock cognate protein 70 is involved in rotavirus cell entry Journal of Virology, 76, 4096-4102.
Ciarlet,M. Isa,P. Conner,M.E. Liprandi,F.
2001. Antigenic and molecular analyses reveal that the equine rotavirus strain H-1 is closely related to porcine, but not equine, rotaviruses: interspecies transmission from pigs to horses? Virus Genes, 22, 5-20.
Guerrero,C.A. Mendez,E. Zarate,S. Isa,P. Lopez,S. Arias,C.F.
2000. Integrin alpha(v)beta(3) mediates rotavirus cell entry Proceedings of the National Academy of Sciences of the United States of America, 97, 14644-14649.
Lopez,S. Espinosa,R. Isa,P. Merchant,M.T. Zarate,S. Mendez,E. Arias,C.F.
2000. Characterization of a monoclonal antibody directed to the surface of MA104 cells that blocks the infectivity of rotaviruses Virology, 273, 160-168.
Isa,P. Lopez,S. Segovia,L. Arias,C.F.
1997. Functional and structural analysis of the sialic acid-binding domain of rotaviruses Journal of Virology, 71, 6749-6756.
Isa,P. Wood,A.R. Netherwood,T. Ciarlet,M. Imagawa,H. Snodgrass,D.R.
1996. Survey of equine rotaviruses shows conservation of one P genotype in background of two G genotypes Archives of Virology, 141, 1601-1612 * .
Isa,P. Snodgrass,D.R.
1994. Serological and genomic characterization of equine rotavirus VP4 proteins identifies three different P serotypes Virology, 201, 364-372 * .
Sestak,K. Isa,P.
1993. [Present findings on rotaviruses with emphasis on rotaviruses in swine].Veterinarni Medicina, 38, 161-186 * .
Libros y capítulos recientes Sanchez-Tacuba,L. Manjarrez-Zavala,M.E. Isa,P. 2019. Patogenia Viral en: Tay Zavala,J. Microbiologia y parasitologia medicas de Tay 5a ed. Mexico. Mendez Editores. pags. 334-342
Sandoval-Jaime,C. Manjarrez-Zavala,M.E. Isa,P. 2019. Orthomyxoviridae en: Sanchez-Vega,J.T. Microbiologia y parasitologia medicas de Tay 5a ed. Mexico. Mendez Editores. pags. 349-356
Isa,P. Taboada,B. Gutierrez,A.L. Chavez,P. del Angel,R.M. Ludert,J.E. Espinosa,A.C. Eguiarte,L.E. Garrido,E. Lopez,S. Souza,V. Arias,C.F. 2018. Hyperdiverse Viral Communities in an Oligotrophic Oasis (Cuatro Cienegas): Marine Affinities and Microgeographic Differentiation en: Eguiarte,L.E. Cuatro Cienegas Ecology, Natural History and Microbiology. Cham. Springer International Publishing. pags. 43-55
Isa,P. 2017. Astroviruses Biology en: Arbiza,J. Human Virology in Latin America: From Biology to Control. Cham. Springer International Publishing. pags. 55-61
Arias,C.F. Silva-Ayala,D. Isa,P. Diaz-Salinas,M.A. 2016. Chapter 2.2 en: Estes,M.K. Viral Gastroenteritis. Boston. Academic Press. pags. 103-119
Arias,C.F. Guerrero,C.A. Mendez,E. Zarate,S. Isa,P. Espinosa,R. Romero,P. Lopez,S. 2001. Early events of rotavirus infection: the search for the receptor(s) en: Goode,J.A. Gastroenteritis Viruses. pags. 47-60 discussion 603.
Otras Publicaciones Arias,C.F. Taboada,B. Moran,P. Isa,P. Serrano-Vazquez,A. Rojas-Velazquez,L. Perez-Juarez,H. Lopez,S. Torres,J. Ximenez,C.
2020. The gut virome of healthy children during the first year of life is diverse and dynamic bioRxiv, Preprint posted October 07, 2020, 2020.
Taboada,B. Vazquez-Perez,J.A. Munoz-Medina,J.E. Ramos-Cervantes,P. Escalera-Zamudio,M. Boukadida,C. Sanchez-Flores,A. Isa,P. Mendieta-Condado,E. Martinez-Orozco,J.A. Becerril-Vargas,E. Salas-Hernandez,J. Grande,R. Gonzalez-Torres,C. Gaytan-Cervantes,F.J. Vazquez,G. Pulido,F. Araiza-Rodriguez,A. Garces-Ayala,F. Gonzalez-Bonilla,C.R. Grajales-Muniz,C. Borja-Aburto,V.H. Barrera-Badillo,G. Lopez,S. Hernandez-Rivas,L. Perez-Padilla,R. Lopez Martinez,I. Avila-Rios,S. Ruiz-Palacios,G. Ramirez-Gonzalez,J.E. Arias,C.F.
2020. Genomic analysis of early SARS-CoV-2 strains introduced in Mexico bioRxiv, Preprint posted May 30, 120402.
Escalera-Zamudio,M. Cobian-Guemes,A.G. Taboada,B. Lopez-Martinez,I. Vazquez-Perez,J.A. Montalvo-Corral,M. Hernandez,J. Diaz-Quinonez,J.A. Barrera-Badillo,G. Lopez,S. Arias,C.F. Isa,P.
2019. Efficient whole genome sequencing of influenza A viruses bioRxiv, Preprint posted August 29, 2019, 749234.
Carrera-Aguirre,V.M. Mercado-Garcia,M.C. Trujillo-Ortega,M.E. Mendoza-Elvira,S.E. Isa-Haspra,P. Paulin-Paz,L.F. Arias-Ortiz,C.F. Sanchez-Betancourt,J.I.
2014. Genetic changes detected in the internal genes of porcine influenza viruses isolated in Mexico Veterinaria México OA, 1, 1-21.
* Indica publicación con otra institución de adscripción
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