IBT-UNAM : Dr. Ruben Paul Gaytan Colin
Publicaciones recientes
Cesa-Luna,C. Baez,A. Aguayo-Acosta,A. Llano-Villarreal,R.C. Juarez-Gonzalez,V.R. Gaytan,P. Bustillos-Cristales,M.D.R. Rivera-Urbalejo,A. Munoz-Rojas,J. Quintero-Hernandez,V.
2020. Growth inhibition of pathogenic microorganisms by Pseudomonas protegens EMM-1 and partial characterization of inhibitory substances PLoS ONE, 15, e0240545.
Navarro-Gonzalez,S.S. Ramirez-Trujillo,J.A. Pena-Chora,G. Gaytan,P. Roldan-Salgado,A. Corzo,G. Lina-Garcia,L.P. Hernandez-Velazquez,V.M. Suarez-Rodriguez,R.
2019. Enhanced Tolerance against a Fungal Pathogen and Insect Resistance in Transgenic Tobacco Plants Overexpressing an Endochitinase Gene from Serratia marcescens International Journal of Molecular Sciences, 20, 3482.
Muslinkina,L. Roldan-Salgado,A. Gaytan,P. Juarez-Gonzalez,V.R. Rudino,E. Pletneva,N. Pletnev,V. Dauter,Z. Pletnev,S.
2019. Structural Factors Enabling Successful GFP-Like Proteins with Alanine as the Third Chromophore-Forming Residues Journal of Molecular Biology, 431, 1397-1408.
Fragoso-Jimenez,J.C. Baert,J. Nguyen,T.M. Liu,W. Sassi,H. Goormaghtigh,F. Van Melderen L. Gaytan,P. Hernandez-Chavez,G. Martinez,A. Delvigne,F. Gosset,G.
2019. Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity Microbial Cell Factories, 18, 26.
Diupotex,M. Martinez-Salazar,M.B. Escalona-Montano,A.R. Zamora-Chimal,J. Salaiza-Suazo,N. Ruiz-Remigio,A. Roldan-Salgado,A. Aguirre-Garcia,M.M. Martinez-Calvillo,S. Gaytan,P. Becker,I.
2019. The mKate fluorescent protein expressed by Leishmania mexicana modifies the parasite immunopathogenicity in BALB/c mice Parasite Immunology, 41, e12608.
Garcia,G. Ramos,F. Maldonado,J. Fernandez,A. Yanez,J. Hernandez,L. Gaytan,P.
2018. Prevalence of two Entamoeba gingivalis ST1 and ST2-kamaktli subtypes in the human oral cavity under various conditions Parasitology Research, 117, 2941-2948.
Koyani,R.D. Andrade,M. Quester,K. Gaytan,P. Huerta-Saquero,A. Vazquez-Duhalt,R.
2018. Surface modification of protein enhances encapsulation in chitosan nanoparticles Applied Nanoscience, 8, 1197-1203.
Gaytan,P. Roldan-Salgado,A. Yanez,J.A. Morales-Arrieta,S. Juarez-Gonzalez,V.R.
2018. CiPerGenesis, a Mutagenesis Approach that Produces Small Libraries of Circularly Permuted Proteins Randomly Opened at a Focused Region: Testing on the Green Fluorescent Protein ACS Combinatorial Science, 20, 400-413.
Garcia,G. Ramos,F. Martinez-Hernandez,F. Hernandez,L. Yanez,J. Gaytan,P.
2018. A new subtype of Entamoeba gingivalis: "E. gingivalis ST2, kamaktli variant" Parasitology Research, 117, 1277-1284.
Llamas-Guillen,B.A. Pastor,N. Lopez-Herrera,G. Gonzalez-Serrano,M.E. Valenzuela-Vazquez,L. Bravo-Adame,M.E. Villanueva-Cabello,T.M. Gaytan,P. Yanez,J. Martinez-Duncker,I. Ruiz-Fernandez,M. Veillette,A. Espinosa-Padilla,S.E. Cruz-Munoz,M.E.
2017. Two novel mutations in ZAP70 gene that result in human immunodeficiency Clinical Immunology, 183, 278-284.
Carcamo,E. Roldan-Salgado,A. Osuna,J. Bello San-Martin,I. Yanez,J.A. Saab-Rincon,G. Viadiu,H. Gaytan,P.
2017. Spiked Genes: A Method to Introduce Random Point Nucleotide Mutations Evenly throughout an Entire Gene Using a Complete Set of Spiked Oligonucleotides for the Assembly ACS Omega, 2, 3183-3191.
Rodriguez-Mejia,J.L. Roldan-Salgado,A. Osuna,J. Merino,E. Gaytan,P.
2017. A Codon Deletion at the Beginning of Green Fluorescent Protein Genes Enhances Protein Expression Journal of Molecular Microbiology and Biotechnology, 27, 1-10.
Sanchez-Montes,S. Guzman-Cornejo,C. Herrera-Montalvo,G. Richman,A.D. Flores-Martinez,J.J. Garcia-Ruiz,G.F. Berzunza-Cruz,M. Gaytan-Colin,P. Perez-Montfort,R. Alcantara-Rodriguez,V.E. Becker,I.
2016. First record of bartonella vinsonii in the sucking louse hoplopleura hirsuta1 collected from hispid cotton rats, sigmodon hispidus, in Mexico Southwestern Entomologist, 41, 1031-1036.
Roldan-Salgado,A. Sanchez-Barreto,C. Gaytan,P.
2016. LanFP10-A, first functional fluorescent protein whose chromophore contains the elusive mutation G67A Gene, 592, 281-290.
Torres-Tejerizo,G. Banuelos,L.A. Cervantes,L. Gaytan,P. Pistorio,M. Romero,D. Brom,S.
2015. Development of molecular tools to monitor conjugative transfer in rhizobia Journal of Microbiological Methods, 117, 155-163.
Noda-Garcia,L. Juarez-Vazquez,A.L. Avila-Arcos,M.C. Verduzco-Castro,E.A. Montero-Moran,G. Gaytan,P. Carrillo-Tripp,M. Barona-Gomez,F.
2015. Insights into the evolution of enzyme substrate promiscuity after the discovery of (betaalpha)8 isomerase evolutionary intermediates from a diverse metagenome BMC Evolutionary Biology, 15, 107.
Quiroz-Castaneda,R.E. Mendoza-Mejia,A. Obregon-Barboza,V. Martinez-Ocampo,F. Hernandez-Mendoza,A. Martinez-Garduno,F. Guillen-Solis,G. Sanchez-Rodriguez,F. Pena-Chora,G. Ortiz-Hernandez,L. Gaytan-Colin,P. Dantan-Gonzalez,E.
2015. Identification of a New Alcaligenes faecalis Strain MOR02 and Assessment of Its Toxicity and Pathogenicity to Insects BioMed Research International, Article ID 570243, .
Garcia,G. Ramos,F. Gutierrez,R. Yanez,J. Salmeron-Estrada,M. Hernandez,L. Martinez-Hernandez,F. Gaytan,P.R.
2014. Molecular epidemiology and genetic diversity of Entamoeba species in a chelonian collection Journal of Medical Microbiology, 63, 271-283.
Noda-Garcia,L. Camacho-Zarco,A.R. Medina-Ruiz,S. Gaytan,P. Carrillo-Tripp,M. Fulop,V. Barona-Gomez,F.
2013. Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer Molecular Biology And Evolution, 30, 2024-2034.
Gaytan,P. Roldan-Salgado,A.
2013. Elimination of Redundant and Stop Codons during the Chemical Synthesis of Degenerate Oligonucleotides. Combinatorial Testing on the Chromophore Region of the Red Fluorescent Protein mKate ACS Synthetic Biology, 2, 453-462.
Gaytan,P. Lopez-Bustos,E. Guereca,L.
2013. Repetitive use of Polyacrylamide Gels for the Analysis and Purification of Oligonucleotides Analytical Biochemistry, 439, 62-64.
Osuna,J. Flores,H. Gaytan,P.
2012. A reporter system that discriminates EF-hand-sensor motifs from signal-modulators at the single-motif level FEBS Letters, 586, 3398-3403.
Gaytan,P. Contreras-Zambrano,C. Ortiz-Alvarado,M. Morales-Pablos,A. Yanez,J.
2009. TrimerDimer: an oligonucleotide-based saturation mutagenesis approach that removes redundant and stop codons Nucleic Acids Research, 37, e125.
Gaytan,P.
2009. Chemical synthesis of oligonucleotides using acetone as a washing solvent Biotechniques, 47, 701-702.
Flores-Ramirez,G. Rivera,M. Morales-Pablos,A. Osuna,J. Soberon,X. Gaytan,P.
2007. The effect of amino acid deletions and substitutions in the longest loop of GFP BMC Chemical Biology, 7, 1.
Monroy-Lagos,O. Soberon,X. Gaytan,P. Osuna,J.
2006. Improvement of an unusual twin-arginine transporter leader Peptide by a codon-based randomization approach Applied and Environmental Microbiology, 72, 3797-3801.
Aguilar-Diaz,H. Bobes,R.J. Carrero,J.C. Camacho-Carranza,R. Cervantes,C. Cevallos,M.A. Davila,G. Rodriguez-Dorantes,M. Escobedo,G. Fernandez,J.L. Fragoso,G. Gaytan,P. Garciarrubio,A. Gonzalez,V.M. Gonzalez,L. Jose,M.V. Jimenez,L. Laclette,J.P. Landa,A. Larralde,C. Morales-Montor,J. Morett,E. Ostoa-Saloma,P. Sciutto,E. Santamaria,R.I. Soberon,X. de la Torre P. Valdes,V. Yanez,J.
2006. The genome project of Taenia solium Parasitology International, 55, S127-S130.
Gaytan,P. Yanez,J. Grande,R. Morett,E. Soberon,X.
2005. Improving random mutagenesis by purification of the oligonucleotide variants Combinatorial Chemistry & High Throughput Screening, 8, 537-544.
Yanez,J. Arguello,M. Osuna,J. Soberon,X. Gaytan,P.
2004. Combinatorial codon-based amino acid substitutions Nucleic Acids Research, 32, e158.
Osuna,J. Yanez,J. Soberon,X. Gaytan,P.
2004. Protein evolution by codon-based random deletions Nucleic Acids Research, 32, e136.
Gaytan,P. Osuna,J. Soberon,X.
2002. Novel ceftazidime-resistance beta-lactamases generated by a codon-based mutagenesis method and selection Nucleic Acids Research, 30, e84-e84.
Gaytan,P. Yanez,J. Sanchez,F. Soberon,X.
2001. Orthogonal combinatorial mutagenesis: a codon-level combinatorial mutagenesis method useful for low multiplicity and amino acid-scanning protocols Nucleic Acids Research, 29, E9.
Gaytan,P. Yanez,J. Sanchez,F. Mackie,H. Soberon,X.
1998. Combination of DMT-mononucleotide and Fmoc-trinucleotide phosphoramidites in oligonucleotide synthesis affords an automatable codon-level mutagenesis method Chemistry and Biology, 5, 519-527.
Gaytan,P. Yanez,J. Soberon,X. Martinez,R.
1997. A new method for oligonucleotide derivatization of the 3' or 5'-termini with a CPG-support carrying the natural product isoargentatin-D Tetrahedron Letters, 38, 6123-6126.
Estrada,G. Colin,L. Gaytan,P. Alagon,A. Lizardi,P.M.
1996. Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids Mol.Cell Probes, 10, 179-185.
Otras Publicaciones
Valdez-Lara,A.G. Andrade-Medina,M. Aleman-Vichis,J.A. Perez-Montoya,A.A. Pineda-Aguilar,N. Martinez-Guerra,E. Gaytan,P. Carrillo-Tripp,M.
2019. Hot-spots and their contribution to the self-assembly of the viral capsid: in-vitro validation bioRxiv, Preprint posted August 06, 2019, 724146.
Carcamo-Noriega,E.N. Martinez-Anaya,C. Gaytan-Colin,P.
2018. Mutando con genes sintéticos: una buena manera de obtener proteínas mejoradas Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 12, 3-5.
Yanez,J. Soberon,X. Gaytan,P.
2004. Rutas alternas de síntesis para la preparación de Fmoc-Trinucleósido-Difosfato Fosforamiditos Revista de la Sociedad Química de México, 48, 26-37.
Patentes
X. Soberón y P. Gaitán 2003 Fmoc-trinucleótido-fosforamiditos y su uso como unidades mutagénicas para la construcción de bibliotecas combinatorias enriquecidas con sustituciones de baja multiplicidad.UNAM México.
X. Soberón y P. Gaitán 2003 Método para la construcción de bibliotecas binomiales de oligodesoxirrubonucleótidos, mutagenizados a nivel de codón utilizando desoxinucleósido-fosforamiditos.UNAM México.
X. Soberón y P. Gaytán 2002 Method for the construction of binomial libraries of oligodeoxyribonucleotides, mutagenized at a codon level using deoxyribonucleoside-phosphoramidities.Europa Canadá 2,391,999 USA10/130,047 a
.
X. Soberón y P. Gaytán 2000 Fmoc-trinucleotide-phosphoramidites and their use as mutagenic units for assembling of combinational libraries enriched with low multiplicity substitutions.UNAM Estados Unidos.
X. Soberón y P. Gaytán 2000 Método para la construcción de bibliotecas binomiales de oligodesoxirrubonucleótidos, mutagenizados a nivel de codón utilizando desoxinucleósido-fosforamiditos.UNAM PCT. (en trámite)
X. Soberón y P. Gayt·n 1999 Fmoc-trinucleótido-fosforamiditos y su uso como unidades mutagénicas para la construcción de bibliotecas combinatorias enriquecidas con sustituciones de baja multiplicidad.UNAM México.
X. Soberón y P. Gayt·n 1999 Método para la construcción de bibliotecas binomiales de oligodesoxirrubonucleótidos, mutagenizados a nivel de codón utilizando desoxinucleósido-fosforamiditos.UNAM México.