Garcia,S. Flores,N. de Anda,R. Hernandez,G. Gosset,G. Bolivar,F. Escalante,A.
2017. The Role of the ydiB Gene, Which Encodes Quinate/Shikimate Dehydrogenase, in the Production of Quinic, Dehydroshikimic and Shikimic Acids in a PTS- Strain of Escherichia coli Journal of Molecular Microbiology and Biotechnology, 27, 11-21.
Fernandez-Alejandre,K.I. Flores,N. Tinoco-Valencia,R. Caro,M. Flores,C. Galindo,E. Serrano-Carreon,L.
2016. Diffusional and transcriptional mechanisms involved in laccases production by Pleurotus ostreatus CP50 Journal of Biotechnology, 223, 42-49.
Cortes,J.T. Flores,N. Bolivar,F. Lara,A.R. Ramirez,O.T.
2016. Physiological effects of pH gradients on Escherichia coli during plasmid DNA production Biotechnology and Bioengineering, 113, 598-611.
Aguilar,C. Flores,N. Riveros-McKay,F. Sahonero-Canavesi,D. Carmona,S.B. Geiger,O. Escalante,A. Bolivar,F.
2015. Deletion of the 2-acyl-glycerophosphoethanolamine cycle improve glucose metabolism in Escherichia coli strains employed for overproduction of aromatic compounds Microbial Cell Factories, 14, 194.
Rodriguez,A. Martinez,J.A. Flores,N. Escalante,A. Gosset,G. Bolivar,F.
2014. Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds Microbial Cell Factories, 13, 126.
Sabido,A. Sigala,J.C. Hernandez-Chavez,G. Flores,N. Gosset,G. Bolivar,F.
2014. Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized Biotechnology and Bioengineering, 111, 1150-1160.
Rodriguez,A. Martinez,J.A. Baez-Viveros,J.L. Flores,N. Hernandez-Chavez,G. Ramirez,O.T. Gosset,G. Bolivar,F.
2013. Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykF Microbial Cell Factories, 12, 86.
Centeno-Leija,S. Utrilla,J. Flores,N. Rodriguez,A. Gosset,G. Martinez,A.
2013. Metabolic and transcriptional response of Escherichia coli with a NADP-dependent glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans Antonie Van Leeuwenhoek, 104, 913-924.
Caspeta,L. Lara,A.R. Perez,N.O. Flores,N. Bolivar,F. Ramirez,O.T.
2013. Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies Journal of Biotechnology, 167, 47-55.
Soria,S. de Anda,R. Flores,N. Romero-Garcia,S. Gosset,G. Bolivar,F. Baez-Viveros,J.L.
2013. New insights on transcriptional responses of genes involved in carbon central metabolism, respiration and fermentation to low ATP levels in Escherichia coli Journal of Basic Microbiology, 53, 365-380.
Aguilar,C. Escalante,A. Flores,N. de Anda,R. Riveros-McKay,F. Gosset,G. Morett,E. Bolivar,F.
2012. Genetic changes during a laboratory adaptive evolution process that allowed fast growth in glucose to an Escherichia coli strain lacking the major glucose transport system BMC Genomics, 13, 385.
Cabrera-Valladares,N. Martinez,L.M. Flores,N. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2012. Physiologic Consequences of Glucose Transport and Phosphoenolpyruvate Node Modifications in Bacillus subtilis 168 Journal of Molecular Microbiology and Biotechnology, 22, 177-197.
Martinez-Gomez,K. Flores,N. Castaneda,H.M. Martinez-Batallar,G. Hernandez-Chavez,G. Ramirez,O.T. Gosset,G. Encarnacion,S. Bolivar,F.
2012. New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during growth on glycerol Microbial Cell Factories, 11, 46.
Baez,A. Flores,N. Bolivar,F. Ramirez,O.T.
2011. Simulation of dissolved CO(2) gradients in a scale-down system: A metabolic and transcriptional study of recombinant Escherichia coli Biotechnology Journal, 6, 959-967.
Olvera,L. Mendoza-Vargas,A. Flores,N. Olvera,M. Sigala,J.C. Gosset,G. Morett,E. Bolivar,F.
2009. Transcription Analysis of Central Metabolism Genes in Escherichia coli. Possible Roles of a38 in Their Expression, as a Response to Carbon Limitation PLoS ONE, 4, e7466.
Baez,A. Flores,N. Bolivar,F. Ramirez,O.T.
2009. Metabolic and transcriptional response of recombinant Escherichia coli to elevated dissolved carbon dioxide concentrations Biotechnology and Bioengineering, 104, 102-110.
Caspeta,L. Flores,N. Perez,N.O. Bolivar,F. Ramirez,O.T.
2009. The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study Biotechnology and Bioengineering, 102, 468-482.
Sigala,J.C. Flores,S. Flores,N. Aguilar,C. de Anda,R. Gosset,G. Bolivar,F.
2009. Acetate Metabolism in Escherichia coli Strains Lacking Phosphoenolpyruvate: Carbohydrate Phosphotransferase System; Evidence of Carbon Recycling Strategies and Futile Cycles Journal of Molecular Microbiology and Biotechnology, 16, 224-235.
Orencio-Trejo,M. Flores,N. Escalante,A. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2008. Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities Biotechnology for Biofuels, 1, 8.
Flores,N. Escalante,A. de Anda,R. Baez-Viveros,J.L. Merino,E. Franco,B. Georgellis,D. Gosset,G. Bolivar,F.
2008. New Insights into the Role of Sigma Factor RpoS as Revealed in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Journal of Molecular Microbiology and Biotechnology, 14, 176-192.
Baez-Viveros,J.L. Flores,N. Suarez,K. Castillo-Espana,P. Bolivar,F. Gosset,G.
2007. Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine Microbial Cell Factories, 6, 30.
Flores,N. Leal,L. Sigala,J.C. de Anda,R. Escalante,A. Martinez,A. Ramirez,O.T. Gosset,G. Bolivar,F.
2007. Growth Recovery on Glucose under Aerobic Conditions of an Escherichia coli Strain Carrying a Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Deletion by Inactivating arcA and Overexpressing the Genes Coding for Glucokinase and Galactose Permease Journal of Molecular Microbiology and Biotechnology, 13, 105-116.
Lara,A.R. Leal,L. Flores,N. Gosset,G. Bolivar,F. Ramirez,O.T.
2006. Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system Biotechnology and Bioengineering, 93, 372-385.
Flores,S. Flores,N. de Anda,R. Gonzalez,A. Escalante,A. Sigala,J.C. Gosset,G. Bolivar,F.
2005. Nutrient-Scavenging Stress Response in an Escherichia coli Strain Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System, as Explored by Gene Expression Profile Analysis Journal of Molecular Microbiology and Biotechnology, 10, 51-63.
Flores,N. Flores,S. Escalante,A. de Anda,R. Leal,L. Malpica,R. Georgellis,D. Gosset,G. Bolivar,F.
2005. Adaptation for fast growth on glucose by differential expression of central carbon metabolism and gal regulon genes in an Escherichia coli strain lacking the phosphoenolpyruvate:carbohydrate phosphotransferase system Metabolic Engineering, 7, 70-87.
Flores,N. de Anda,R. Flores,S. Escalante,A. Hernandez,G. Martinez,A. Ramirez,O.T. Gosset,G. Bolivar,F.
2004. Role of Pyruvate Oxidase in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Journal of Molecular Microbiology and Biotechnology, 8, 209-221.
Flores,S. Gosset,G. Flores,N. de Graaf,A.A. Bolivar,F.
2002. Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by 13C labelling and NMR spectroscopy Metabolic Engineering, 4, 124-137.
Siguenza,R. Flores,N. Hernandez,G. Martinez,A. Bolivar,F. Valle,F.
1999. Kinetic characterization in batch and continuous culture of Escherichia coli mutants affected in phosphoenolpyruvate metabolism: differences in acetic acid production World Journal Of Microbiology & Biotechnology, 15, 587-592.
Flores,N. Xiao,J. Berry,A. Bolivar,F. Valle,F.
1996. Pathway engineering for the production of aromatic compounds in Escherichia coli Nature Biotechnology, 14, 620-623.
Valle,F. Munoz,E. Ponce,E. Flores,N. Bolivar,F.
1996. Basic and applied aspects of metabolic diversity: The phosphoenolpyruvate node Journal of Industrial Microbiology & Biotechnology, 17, 458-462.
Ponce,E. Flores,N. Martinez,A. Valle,F. Bolivar,F.
1995. Cloning of the two pyruvate kinase isoenzyme structural genes from Escherichia coli: the relative roles of these enzymes in pyruvate biosynthesis Journal of Bacteriology, 177, 5719-5722.
Castano,I. Flores,N. Valle,F. Covarrubias,A.A. Bolivar,F.
1992. gltF, a member of the gltBDF operon of Escherichia coli, is involved in nitrogen-regulated gene expression Molecular Microbiology, 6, 2733-2741.
Flores,N. Valle,F. Bolivar,F. Merino,E.
1992. Recovery of DNA from agarose gels stained with methylene blue.Biotechniques, 13, 203-205.
Oliver,G. Gosset,G. Sanchez-Pescador,R. Lozoya,E. Ku,L.M. Flores,N. Becerril,B. Valle,F. Bolivar,F.
1987. Determination of the nucleotide sequence for the glutamate synthase structural genes of Escherichia coli K-12 Gene, 60, 1-11.
Balbas,P. Soberon,X. Merino,E. Zurita,M. Lomeli,H. Valle,F. Flores,N. Bolivar,F.
1986. Plasmid vector pBR322 and its special-purpose derivatives--a review Gene, 50, 3-40.
Flores,N. de Anda,R. Guereca,L. Cruz,N. Antonio,S. Balbas,P. Bolivar,F. Valle,F.
1986. A new expression vector for the production of fused proteins in Escherichia coli Applied Microbiology and Biotechnology, 25, 267-271.
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