IBT-UNAM : Dra. Laura Alicia Palomares Aguilera
Dra. Laura Alicia Palomares Aguilera Grupo
Departamento de Medicina Molecular y Bioprocesos
Líneas de investigación
Teléfonos
Oficina +52 (777) 329-1646 red UNAM 27646 +52 (777) 311-4900 ext 206 Laboratorio +52 (777) 329-1617 red UNAM 27617 +52 (777) 311-4900 ext 206
- Licenciatura: Ingeniera Bioquimica, Instituto Tecnologico y de Estudios Superiores de Monterrey (1990)
Premio Universidad Nacional en Innovación Tecnológica y Diseño Industrial 2018 UNAM (2018) Mención Honorífica del Premio Alfredo Sánchez Marroquín por su tesis de doctorado Diseño de estrategias de producción de partículas pseudovirales de rotavirus bovino en levaduras mediante herramientas moleculares y de bioproceso" Sociedad Mexicana de Biotecnología y Bio Mexico (2013) Premio Sor Juana Inés de la Cruz Universidad Nacional Autónoma de México (2012) Premio Canifarma Veterinaria. 1er lugar en la modalidad de desarrollo tecnológico (2010) Premio de la Academia Mexicana de Ciencias en el área de Ingeniería y Tecnología (2009) Premio Canifarma Veterinaria. 1er lugar en la modalidad de desarrollo tecnológico.Trabajo Desarrollo de una vacuna recombinante contra rotavirus bovinos prevalecientes en México (2009) Distinción Universidad Nacional para Jóvenes Académicos en en área de Innovación Tecnológica y Diseño Industrial (2007) Premio Morelense al Mérito Científico Fondo Mixto de Fomento a la Investigación Científica y Tecnológica CONACYT-Gobierno del Estado de Morelos (2005) Premio Carlos Casas Campillo 2004 Sociedad Mexicana de Biotecnología y bioingeniería (2004) Premio Weizmann Kahn a la mejor tesis de doctorado en el área de Investigación Tecnológica (2001) Premio Alfredo Sanchez Marroquin a la mejor tesis de doctorado Sociedad Mexicana de Biotecnologia y Bioingenieria (2001) Medalla Alfonso Caso 1999 UNAM (1999)
Estudiantes Diana Berenice Silva
Ing. Alonso Ulises Pérez
Lic. Enrique Paz
M.C. Violeta Guadarrama
M.V.Z. Yahel Francisco López
M.C. Juan Carlos Rivera
Lic. Stfanny Wendy Meza
M.C. Esmeralda Cuevas
Lic. Arturo Liñan
Ing. Ricardo Antonio González
Publicaciones recientes
Rodriguez,M. Castro-Acosta,R.M. Ruiz-Morales,E.R. Villanueva-Flores,F. Ramirez,O.T. Palomares,L.A.
2021. A novel method for the in vitro assembly of virus-like particles and multimeric proteins Biotechnology Letters, Feb 27 Online ahead of print, .
Bulte,D.B. Palomares,L.A. Gomez-Parra,C. Martinez,J.A. Contreras,M.A. Noriega,L.G. Ramirez,O.T.
2020. Overexpression of the Mitochondrial Pyruvate Carrier reduces lactate production and increases recombinant protein productivity in CHO cells Biotechnology and Bioengineering, 117, 2633-2647.
Martinez,J.A. Bulte,D.B. Contreras,M.A. Palomares,L.A. Ramirez,O.T.
2020. Dynamic Modeling of CHO Cell Metabolism Using the Hybrid Cybernetic Approach With a Novel Elementary Mode Analysis Strategy Frontiers in Bioengineering and Biotechnology, 8, 279.
Villanueva-Flores,F. Castro-Lugo,A. Ramirez,O.T. Palomares,L.A.
2020. Understanding cellular interactions with nanomaterials: Towards a rational design of medical nanodevices Nanotechnology, 31, 132002.
Pastor,A.R. Gonzalez-Dominguez,G. Diaz-Salinas,M.A. Ramirez,O.T. Palomares,L.A.
2019. Defining the multiplicity and time of infection for the production of Zaire Ebola virus-like particles in the insect cell-baculovirus expression system Vaccine, 37, 6962-6969.
Garcia-Garcia,W.I. Vidal-Limon,A. Arrocha-Arcos,A.A. Palomares,L.A. Ramirez,O.T. Miranda-Hernandez,M.
2019. Rotavirus VP6 protein as a bio-electrochemical scaffold: Molecular dynamics and experimental electrochemistry Bioelectrochemistry, 127, 180-186.
Villanueva-Flores,F. Miranda-Hernandez,M. Flores-Flores,J.O. Porras-Sanjuanico,A. Hu,H. Perez-Martinez,L. Ramirez,O.T. Palomares,L.A.
2019. Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release Journal of Materials Science, 54, 7867-7882.
Espiritu-Ramirez,P. Ortega-Balderas,N.Y. Sevilla-Tapia,L. Montiel-Martinez,A.G. Pastor-Flores,A.R. Palomares,L.A. Torres-Vega,M.A.
2018. Gene therapy for treatment of chronic hyperammonemia in a rat model of hepatic encephalopathy Annals of Hepatology, 17, 1026-1034.
Alcala,A.C. Palomares,L.A. Ludert,J.E.
2018. Secretion of the non-structural protein 1 of dengue virus from infected mosquito cells: facts and speculations Journal of Virology, 92, e00275-18.
Palomares,L.A. Mukhopadhyay,T.K. Genzel,Y. Lua,L.H.L. Cox,M.M.J.
2018. Vaccine Technology VI: Innovative and integrated approaches in vaccine development [Editorial] Vaccine, 36, 3061-3063.
Gomez,I.A. Hernandez,V. Palomares,L.A. Ramirez,O.T.
2018. Flocculation of CHO cells for primary separation of recombinant glycoproteins: Effect on glycosylation profiles Biochemical Engineering Journal, 132, 244-254.
Hidalgo,D. Paz,E. Palomares,L.A. Ramirez,O.T.
2017. Real-time imaging reveals unique heterogeneous population features in insect cell cultures Journal of Biotechnology, 259, 56-62.
Ospina-Orejarena,A. Vera-Graziano,R. Castillo-Ortega,M.M. Hinestroza,J.P. Rodriguez-Gonzalez,M. Palomares-Aguilera,L. Morales-Moctezuma,M. Maciel-Cerda,A.
2016. Grafting collagen on poly (lactic acid) by a simple route to produce electrospun scaffolds, and their cell adhesion evaluation Tissue Engineering and Regenerative Medicine, 13, 375-387.
Mendoza-Perez,E. Hernandez,V. Palomares,L.A. Serrato,J.A.
2016. An integrated system for synchronous culture of animal cells under controlled conditions Biotechniques, 61, 129-136.
Carreno-Fuentes,L. Bahena,D. Palomares,L.A. Ramirez,O.T. Jose-Yacaman,M. Plascencia-Villa,G.
2016. Molecular docking and aberration-corrected STEM of palladium nanoparticles on viral templates Metals, 6, .
Lappalainen,S. Pastor,A.R. Malm,M. Lopez-Guerrero,V. Esquivel-Guadarrama,F. Palomares,L.A. Vesikari,T. Blazevic,V.
2015. Protection against live rotavirus challenge in mice induced by parenteral and mucosal delivery of VP6 subunit rotavirus vaccine Archives of Virology, 160, 2075-2078.
Meghrous,J. Khramtsov,N. Buckland,B.C. Cox,M.M. Palomares,L.A. Srivastava,I.K.
2015. Dissolved carbon dioxide determines the productivity of a recombinant hemagglutinin component of an influenza vaccine produced by insect cells Biotechnology and Bioengineering, 112, 2267-2275.
Torres-Vega,M.A. Vargas-Jeronimo,R.Y. Montiel-Martinez,A.G. Munoz-Fuentes,R.M. Zamorano-Carrillo,A. Pastor,A.R. Palomares,L.A.
2015. Delivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia Gene Therapy, 22, 58-64.
Carreno-Fuentes,L. Plascencia-Villa,G. Palomares,L.A. Moya,S.E. Ramirez,O.T.
2014. Modulating the physicochemical and structural properties of gold-functionalized protein nanotubes through thiol surface modification Langmuir, 30, 14991-14998.
Plascencia-Villa,G. Carreno-Fuentes,L. Bahena,D. Jose-Yacaman,M. Palomares,L.A. Ramirez,O.T.
2014. Characterization of conductive nanobiomaterials derived from viral assemblies by low-voltage STEM imaging and Raman scattering Nanotechnology, 25, 385706.
Sanchez-Sanchez,L. Cadena-Nava,R.D. Palomares,L.A. Ruiz-Garcia,J. Koay,M.S. Cornelissen,J.J. Vazquez-Duhalt,R.
2014. Chemotherapy pro-drug activation by biocatalytic virus-like nanoparticles containing cytochrome P450 Enzyme and Microbial Technology, 60, 24-31.
Lappalainen,S. Pastor,A.R. Tamminen,K. Lopez-Guerrero,V. Esquivel-Guadarrama,F. Palomares,L.A. Vesikari,T. Blazevic,V.
2014. Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo Human Vaccines and Immunotherapeutics, 10, 2039-2047.
Rodriguez-Limas,W.A. Pastor,A.R. Esquivel-Soto,E. Esquivel-Guadarrama,F. Ramirez,O.T. Palomares,L.A.
2014. Immunogenicity and protective efficacy of yeast extracts containing rotavirus-like particles: A potential veterinary vaccine Vaccine, 32, 2794-2798.
Pastor,A.R. Rodriguez-Limas,W.A. Contreras,M.A. Esquivel,E. Esquivel-Guadarrama,F. Ramirez,O.T. Palomares,L.A.
2014. The assembly conformation of rotavirus VP6 determines its protective efficacy against rotavirus challenge in mice Vaccine, 32, 2874-2877.
Castro-Acosta,R.M. Rodriguez-Limas,W.A. Valderrama,B. Ramirez,O.T. Palomares,L.A.
2014. Effect of metal catalyzed oxidation in recombinant viral protein assemblies Microbial Cell Factories, 13, 25.
Rodriguez-Romero,A. Hernandez-Santoyo,A. Fuentes-Silva,D. Palomares,L.A. Munoz-Cruz,S. Yepez-Mulia,L. Orozco-Martinez,S.
2014. Structural analysis of the endogenous glycoallergen Hev b 2 (endo-beta-1,3-glucanase) from Hevea brasiliensis and its recognition by human basophils Acta Crystallographica Section D: Biological Crystallography, 70, 329-341.
Rodriguez,M. Wood,C. Sanchez-Lopez,R. Castro-Acosta,R.M. Ramirez,O.T. Palomares,L.A.
2014. Understanding internalization of rotavirus VP6 nanotubes by cells: towards a recombinant vaccine Archives of Virology, 159, 1005-1015.
Plascencia-Villa,G. Medina,A. Palomares,L.A. Ramirez,O.T. Ascencio,J.A.
2013. Structural Characterization of Rotavirus-Directed Synthesis and Assembly of Metallic Nanoparticle Arrays Journal of Nanoscience and Nanotechnology, 13, 5572-5579.
Carreno-Fuentes,L. Ascencio,J.A. Medina,A. Aguila,S. Palomares,L.A. Ramirez,O.T.
2013. Strategies for specifically directing metal functionalization of protein nanotubes: constructing protein coated silver nanowires Nanotechnology, 24, 235602.
Clement,H. Olvera,A. Rodriguez,M. Zamudio,F. Palomares,L.A. Possani,L.D. Odell,G.V. Alagon,A. Sanchez-Lopez,R.
2012. Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom Toxicon, 60, 1223-1227.
Chavez,N.A. Jauregui,J. Palomares,L.A. Macias,K.E. Jimenez,M. Salinas,E.
2012. A highly sensitive sandwich ELISA for the determination of glycomacropeptide to detect liquid whey in raw milk Dairy Science & Technology, 92, 121-132.
Palomares,L.A. Mena,J.A. Ramirez,O.T.
2012. Simultaneous expression of recombinant proteins in the insect cell-baculovirus system: Production of virus-like particles Methods, 56, 389-395.
Rodriguez-Limas,W.A. Tyo,K.E. Nielsen,J. Ramirez,O.T. Palomares,L.A.
2011. Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiae Microbial Cell Factories, 10, 33.
Plascencia-Villa,G. Mena,J.A. Castro-Acosta,R.M. Fabian,J.C. Ramirez,O.T. Palomares,L.A.
2011. Strategies for the purification and characterization of protein scaffolds for the production of hybrid nanobiomaterials Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 879, 1105-1111.
Gallo-Ramirez,L.E. Ramirez,O.T. Palomares,L.A.
2011. Intracellular localization of adeno-associated viral proteins expressed in insect cells Biotechnology Progress, 27, 483-493.
Castro-Acosta,R.M. Revilla,A.L. Ramirez,O.T. Palomares,L.A.
2010. Separation and quantification of double- and triple-layered rotavirus-like particles by CZE Electrophoresis, 31, 1376-1381.
Plascencia-Villa,G. Saniger,J.M. Ascencio,J.A. Palomares,L.A. Ramirez,O.T.
2009. Use of recombinant rotavirus VP6 nanotubes as a multifunctional template for the synthesis of nanobiomaterials functionalized with metals Biotechnology and Bioengineering, 104, 871-881.
Mellado,M.C. Mena,J.A. Lopes,A. Ramirez,O.T. Carrondo,M.J. Palomares,L.A. Alves,P.M.
2009. Impact of physicochemical parameters on in vitro assembly and disassembly kinetics of recombinant triple-layered rotavirus-like particles Biotechnology and Bioengineering, 104, 674-686.
Rodriguez-Limas,W.A. Flores-Samaniego,B. de la Mora G. Ramirez,O.T. Palomares,L.A.
2009. Genotypification of bovine group A rotavirus in Mexico Vaccine, 27, 6411-6414.
Vite-Vallejo,O. Palomares,L.A. Dantan-Gonzalez,E. Ayala-Castro,H.G. Martinez-Anaya,C. Valderrama,B. Folch-Mallol,J.
2009. The role of N-glycosylation on the enzymatic activity of a Pycnoporus sanguineus laccase Enzyme and Microbial Technology, 45, 233-239.
Palomares,L.A. Ramirez,O.T.
2009. Challenges for the production of virus-like particles in insect cells: the case of rotavirus-like particles Biochemical Engineering Journal, 45, 158-167.
Rodriguez-Galvan,A. Heredia,A. Plascencia-Villa,G. Ramirez,O.T. Palomares,L.A. Basiuk,V.A.
2008. Scanning Tunneling Microscopy of Rotavirus VP6 Protein Self-Assembled into Nanotubes and Nanospheres Journal of Scanning Probe Microscopy, 3, 25-31.
Chavez,N.A. Salinas,E. Jauregui,J. Palomares,L.A. Macias,K.
2008. Detection of bovine milk adulterated with cheese whey by western blot immunoassay Food and Agricultural Immunology, 19, 265-272.
Dantan-Gonzalez,E. Vite-Vallejo,O. Martinez-Anaya,C. Mendez-Sanchez,M. Gonzalez,M.C. Palomares,L.A. Folch-Mallol,J.
2008. Production of two novel laccase isoforms by a thermotolerant strain of Pycnoporus sanguineus isolated from an oil-polluted tropical habitat International Microbiology, 11, 163-169.
Fuentes-Silva,D. Mendoza-Hernandez,G. Stojanoff,V. Palomares,L.A. Zenteno,E. Torres-Larios,A. Rodriguez-Romero,A.
2007. Crystallization and identification of the glycosylated moieties of two isoforms of the main allergen Hev b 2 and preliminary X-ray analysis of two polymorphs of isoform II Acta Crystallographica Section F: Structural Biology Communications, 63, 787-791.
Mena,J.A. Ramirez,O.T. Palomares,L.A.
2007. Population kinetics during simultaneous infection of insect cells with two different recombinant baculoviruses for the production of virus-like particles BMC Biotechnology, 7, 39.
Serrato,J.A. Hernandez,V. Estrada-Mondaca,S. Palomares,L.A. Ramirez,O.T.
2007. Differences in the glycosylation profile of a monoclonal antibody produced by hybridomas cultured in serum-supplemented, serum-free or chemically defined media Biotechnology and Applied Biochemistry, 47, 113-124.
Lara,A.R. Galindo,E. Ramirez,O.T. Palomares,L.A.
2006. Living With Heterogeneities in Bioreactors: Understanding the Effects of Environmental Gradients on Cells Molecular Biotechnology, 34, 355-382.
Benavides,J. Mena,J.A. Cisneros-Ruiz,M. Ramirez,O.T. Palomares,L.A. Rito-Palomares,M.
2006. Rotavirus-like particles primary recovery from insect cells in aqueous two-phase systems Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 842, 48-57.
Mena,J.A. Ramirez,O.T. Palomares,L.A.
2006. Intracellular distribution of rotavirus structural proteins and virus-like particles expressed in the insect cell-baculovirus system Journal of Biotechnology, 122, 443-452.
Mena,J.A. Ramirez,O.T. Palomares,L.A.
2005. Quantification of rotavirus-like particles by gel permeation chromatography Journal of Chromatography B, 824, 267-276.
Lipscomb,M.L. Palomares,L.A. Hernandez,V. Ramirez,O.T. Kompala,D.S.
2005. Effect of Production Method and Gene Amplification on the Glycosylation Pattern of a Secreted Reporter Protein in CHO Cells Biotechnology Progress, 21, 40-49.
Serrato,J.A. Palomares,L.A. Meneses-Acosta,A. Ramirez,O.T.
2004. Heterogeneous conditions in dissolved oxygen affect N-glycosylation but not productivity of a monoclonal antibody in hybridoma cultures Biotechnology and Bioengineering, 88, 176-188.
Palomares,L.A. Lopez,S. Ramirez,O.T.
2004. Utilization of oxygen uptake rate to assess the role of glucose and glutamine in the metabolism of infected insect cell cultures Biochemical Engineering Journal, 19, 87-93.
Mena,J.A. Ramirez,O.T. Palomares,L.A.
2003. Titration of Non-Occluded Baculovirus Using a Cell Viability Assay Biotechniques, 34, 260-264.
Palomares,L.A. Joosten,C.E. Hughes,P.R. Granados,R.R. Shuler,M.L.
2003. Novel insect cell line capable of complex N-glycosylation and sialylation of recombinant proteins Biotechnology Progress, 19, 185-192.
Palomares,L.A. Lopez,S. Ramirez,O.T.
2002. Strategies for manipulating the relative concentration of recombinant rotavirus structural proteins during simultaneous production by insect cells Biotechnology and Bioengineering, 78, 635-644.
Taticek,R.A. Choi,C. Phan,S.E. Palomares,L.A. Shuler,M.L.
2001. Comparison of growth and recombinant protein expression in two different insect cell lines in attached and suspension culture Biotechnology Progress, 17, 676-684.
Petricevich,V.L. Palomares,L.A. Gonzalez,M. Ramirez,O.T.
2001. Parameters that determine virus adsorption kinetics: toward the design of better infection strategies for the insect cell Enzyme and Microbial Technology, 29, 52-61.
Palomares,L.A. Pedroza,J.C. Ramirez,O.T.
2001. Cell size as a tool to predict the production of recombinant protein by the insect-cell baculovirus expression system Biotechnology Letters, 23, 359-364.
Palomares,L.A. Gonzalez,M. Ramirez,O.T.
2000. Evidence of Pluronic F-68 direct interaction with insect cells: impact on shear protection, recombinant protein, and baculovirus production* Enzyme and Microbial Technology, 26, 324-331.
Mendonca,R.Z. Palomares,L.A. Ramirez,O.T.
1999. An insight into insect cell metabolism through selective nutrient manipulation Journal of Biotechnology, 72, 61-75.
Palomares,L.A. Ramirez,O.T.
1996. The effect of dissolved oxygen tension and the utility of oxygen uptake rate in insect cell culture Cytotechnology, 22, 225-237.
Libros y capítulos recientes Palomares,L.A. Ramirez,O.T. 2019. Hydrodynamic stress and heterogeneities in animal cell culture en: Moo-Young,M. Comprehensive Biotechnology. pags. 108-118
Palomares,L.A. Srivastava,I.K. Ramirez,O.T. Cox,M.M.J. 2018. Glycobiotechnology of the Insect Cell-Baculovirus Expression System Technology en: Reichl,U. Advances in Biochemical Engineering/Biotechnology. Glycobiology. Springer.
Castro-Peralta,F. Cuevas-Juarez,E. Palomares,L.A. 2017. La virología en la industria farmaceútica en: *arias La Virología en México Situación Actual, Retos y Oportunidades. México. Red Mexicana de Virología y Academia Mexicana de Ciencias. pags. 145-157
Lara,A. Palomares,L.A. Ramirez,O.T. 2016. Scale-Down: Simulating Large-Scale Cultures in the Laboratory en: Wittmann,C. Industrial Biotechnology Products and Processes. Weinheim, Alemania. Wiley-VCH Verlag GmbH & Co. KGaA. pags. 55-79
Palomares,L.A. Realpe,M. Ramirez,O.T. 2015. An Overview of Cell Culture Engineering for the Insect Cell-Baculovirus Expression Vector System (BEVS) en: Al-Rubeai,M. Animal Cell Culture. Springer International Publishing. pags. 501-519
Palomares,L.A. Lara,A. Ramirez,O.T. 2010. Bioreactor Scale-Up en: Flickinger,M. Encyclopedia of Industrial Biotechnology Bioprocess, Bioseparation and Cell Technology. New York. John Wiley and Sons.
Palomares,L.A. Lara,A. Ramirez,O.T. 2010. Bioreactor Scale-Down en: Flickinger,M. Encyclopedia of Industrial Biotechnology. New York. John Wiley and Sons.
Palomares,L.A. Valdez-Cruz,N.A. Ramirez,O.T. 2008. Superando los retos del cultivo de células animales a través de la bioingeniería en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 33. Mexico, D.F.. UNAM. pags. 385-398
Palomares,L.A. Ramirez,O.T. 2007. Glicosilación de proteínas recombinantes: Importancia y relación con las condiciones de bioproceso en: Juaresti,E. Diseño y producción de fármacos. Mexico. El Colegio Nacional. pags. 95-123
Palomares,L.A. Estrada-Mondaca,S. Ramirez,O.T. 2006. Principles and applications of the insect cell-baculovirus expression vector system en: Ozturk,S.S. CELL CULTURE TECHNOLOGY FOR PHARMACEUTICAL AND CELL-BASED THERAPIES. Boca Raton, Florida. CRC PRESS. pags. 627-692
Palomares,L.A. Estrada-Mondaca,S. Ramirez,O.T. 2004. Production of recombinant proteins: challenges and solutions en: Lorence,A. Recombinant Gene Expression Reviews and Protocols. pags. 15-52
Palomares,L.A. Kuri Breña,K. Ramirez,O.T. 2002. Industrial recombinant protein production en: Gobaisi,A. Encyclopedia of Life Support Systems. Oxford. EOLSS Publishers. pags. 1-48
Palomares,L.A. Ramirez,O.T. 2000. Bioreactor scale-down en: Spier,R.E. Encyclopedia of cell technology. Wiley. pags. 174-183
Palomares,L.A. Ramirez,O.T. 2000. Bioreactor scale-up en: Spier,R.E. Encyclopedia of Cell Technology. John Wiley and Sons. pags. 183-201
Palomares,L.A. Lopez,S. Ramirez,O.T. 1999. Multiplicity and time of infection as tools to maximise virus-like particle production by insect cells en: Wurm,F. Animal cell technology: products form cells, cells as products. Kluwer. pags. 347-349
Otras Publicaciones Palomares,L.A. Lee,W.H. Ramirez,O.T.
2020. Hacia la soberanía en salud: aportaciones de la investigación científica de la UNAM y de su Instituto de Biotecnología en la lucha contra el covid-19 Pluralidad y Consenso, 10, 24-35.
Alcala,A.C. Maravillas,J.L. Meza,D. Ramirez,O.T. Ludert,J.E. Palomares,L.A.
2019. The dengue virus non-structural protein 1 (NS1) use the scavenger receptor B1 as cell receptor in human hepatic and mosquito cells bioRxiv, Preprint posted December 11, 2019, 871988.
Palomares,L.A. Cuevas-Juarez,E. Lopez-Macias,C.
2019. Influenza, retos y la importancia de vacunar Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 19, 23-27.
Zuniga-Banuelos,F.J. Palomares,L.A.
2016. El Potencial Redox Intracelular y su Importancia en Biotecnología Biotecnologia, 20, 11-25.
Palomares,L.A. Buckland,B.C. Genzel,Y. Cox,M.M.
2015. Vaccine Technology V: The art of taking vaccines to disease prevention Vaccine, 33, 4219-4220.
Plascencia-Villa,G. Palomares,L.A. Ramirez,O.T.
2011. Síntesis y Ensamblaje de Nanomateriales Usando Proteínas Virales Como Templados Biotecnologia, 15, 50-77.
Chavez-Pena,C. Ayala-Mendivil,N.A. Ramirez,O.T. Palomares,L.A.
2010. Efecto de la densidad celular y la multiplicidad de infeccion sobre la produccion de baculovirus recombinantes en cultivos de celulas de insecto TIP revista especializada en Ciencias Quimico-Biologicas, 13, 65-72.
Palomares,L.A. Valencia,R.
2010. Vaccine Technology III Conference Reviews in Environmental Science and Bio-Technology, 9, 315-316.
Plascencia-Villa,G. Ramirez-Reivich,O.T. Palomares-Aguilera,L.
2009. Nanobiomateriales creados a partir de virus Hypatia, 31, .
Martinez-Duncker,I. Palomares-Aguilera,L. Sanchez-Francia,D. Mollicone,R. Ibarra-Gonzalez,I.
2008. Trastornos congénitos de la glicosilación: abordaje clínico y de laboratorio Acta Pediatrica de Mexico, 29, 78-88.
Rodriguez-Limas,W.A. Ramirez,O.T. Palomares,L.A.
2007. Identificación de genotipos de rotavirus bovino prevalecientes en México como herramienta para el desarrollo de una vacuna recombinante Biotecnologia, 10, 34-41.
Palomares,L.A. Ramirez,O.T.
2002. El sistema de celulas de insecto-baculovirus: una alternativa para la produccion de pseudo-particulas virales y otras proteinas recombinantes.Biotecnologia, 6, 16-29.
Palomares,L.A. Ramirez,O.T.
2002. Complex N-glycosylation of Recombinant Proteins by Insect Cells Bioprocessing, 1, 70-73.
Patentes Laura Alicia Palomares Aguilera, Ricardo Martín Castro Acosta, Octavio Tonatiuh Ramírez Reivich, Alma Luisa Revilla Vázquez 2009 Método analítico para la cuantificación diferenciada de estructuras virales proteicas multiméricas.UNAM México.
O. T. Ramírez Reivich, G. Plascencia Villa, L. A. Palomares A., Y. A. Mena Mendez y J. M. Saniger Blesa 2008 Uso de proteínas multiméricas virales como templados para la construcción de nanobiomateriales.UNAM PCT. (en trámite)
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