IBT-UNAM : Dr. Ignacio Lopez Gonzalez
Dr. Ignacio Lopez Gonzalez
Grupo del Dr. Takuya Nishigaki
email: iglogo @ibt.unam.mx
Teléfonos
Oficina +52 (777) 311-4900 ext 234 Laboratorio +52 (777) 329-1611 red UNAM 27611 +52 (777) 311-4900 ext 234
- Doctorado: en Ciencias Bioquímicas IBt-UNAM (2002)
Estudiantes Bryan Alexis Alvarado
Ing. Andrea Zacnite Cuevas
Valery Itzxchel Escobedo
Publicaciones recientes
Garza-Lopez,E. Aldana,A. Darszon,A. Nishigaki,T. Lopez-Gonzalez,I.
2020. CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in its domains I/II Cell Calcium, 89, 102214.
Darszon,A. Nishigaki,T. Lopez-Gonzalez,I. Visconti,P.E. Trevino,C.L.
2020. Differences and Similarities: The Richness of Comparative Sperm Physiology Physiology (Bethesda.), 35, 196-208.
Bondarenko,O. Corzo,G. Santana,F.L. del Rio-Portilla,F. Darszon,A. Lopez-Gonzalez,I.
2019. Non-enzymatically oxidized arachidonic acid regulates T-type Ca(2+) currents in mouse spermatogenic cells FEBS Letters, 593, 1735-1750 [Preprint anteriormente en biorXiv].
Santana-Calvo,C. Romero,F. Lopez-Gonzalez,I. Nishigaki,T.
2018. Robust evaluation of intermolecular FRET using a large Stokes shift fluorophore as a donor Biotechniques, 65, 211-218.
Garza-Lopez,E. Chavez,J.C. Santana-Calvo,C. Lopez-Gonzalez,I. Nishigaki,T.
2016. Cd2+ sensitivity and permeability of a low voltage-activated Ca2+ channel with CatSper-like selectivity filter Cell Calcium, 60, 41-50.
Lopez-Gonzalez,I. Trevino,C.L. Darszon,A.
2016. Regulation of Spermatogenic Cell T-Type Ca Currents by Zn : Implications in Male Reproductive Physiology Journal of Cellular Physiology, 231, 659-667.
Sanchez-Carranza,O. Torres-Rodriguez,P. Darszon,A. Trevino,C.L. Lopez-Gonzalez,I.
2015. Pharmacology of hSlo3 channels and their contribution in the capacitation-associated hyperpolarization of human sperm Biochemical and Biophysical Research Communications, 466, 554-559.
Garza-Lopez,E. Sanchez-Carranza,O. Nishigaki,T. Lopez-Gonzalez,I.
2015. Pharmacological identification of endogenous slo1 channel-b1 subunit complexes in CHO cells using three aKTx1 subfamily toxins International Journal of Pharmacy & Therapeutics, 6, 11-24.
Lopez-Gonzalez,I. Torres-Rodriguez,P. Sanchez-Carranza,O. Solis-Lopez,A. Santi,C.M. Darszon,A. Trevino,C.L.
2014. Membrane Hyperpolarization during Human Sperm Capacitation Molecular Human Reproduction, 20, 619-629.
Darszon,A. Sanchez-Cardenas,C. Orta,G. Sanchez-Tusie,A.A. Beltran,C. Lopez-Gonzalez,I. Granados-Gonzalez,G. Trevino,C.L.
2012. Are TRP channels involved in sperm development and function? Cell and Tissue Research, 349, 749-764.
Hernandez-Vargas,R. Fonseca-Ornelas,L. Lopez-Gonzalez,I. Riesgo-Escovar,J. Zurita,M. Reynaud,E.
2011. Synphilin suppresses a-synuclein neurotoxicity in a Parkinson's disease Drosophila model Genesis, 49, 392-402.
Castillo,E. Lopez-Gonzalez,I. De Regil-Hernandez,R. Reyes-Duarte,D. Sanchez-Herrera,D. Lopez-Munguia,A. Darszon,A.
2007. Enzymatic synthesis of capsaicin analogs and their effect on the T-type Ca(2+) channels Biochemical and Biophysical Research Communications, 356, 424-430.
Rodriguez-Valentin,R. Lopez-Gonzalez,I. Jorquera,R. Labarca,P. Zurita,M. Reynaud,E.
2006. Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic Journal of Cellular Physiology, 209, 183-198.
Hernandez-Gonzalez,E.O. Sosnik,J. Edwards,J. Acevedo,J.J. Mendoza-Lujambio,I. Lopez-Gonzalez,I. Demarco,I. Wertheimer,E. Darszon,A. Visconti,P.E.
2006. Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm Journal of Biological Chemistry, 281, 5623-5633.
Sandoz,G. Lopez-Gonzalez,I. Grunwald,D. Bichet,D. Altafaj,X. Weiss,N. Ronjat,M. Dupuis,A. De Waard,M.
2004. Cav{beta}-subunit displacement is a key step to induce the reluctant state of P/Q calcium channels by direct G protein regulation Proceedings of the National Academy of Sciences of the United States of America, 101, 6267-6272 * .
Sandoz,G. Lopez-Gonzalez,I. Stamboulian,S. Weiss,N. Arnoult,C. De Waard,M.
2004. Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation European Journal of Neuroscience, 19, 1759-1772 * .
Trevino,C.L. Felix,R. Castellano,L.E. Gutierrez,C. Rodriguez,D. Pacheco,J. Lopez-Gonzalez,I. Gomora,J.C. Tsutsumi,V. Hernandez-Cruz,A. Fiordelisio,T. Scaling,A.L. Darszon,A.
2004. Expression and differential cell distribution of low-threshold Ca(2+) channels in mammalian male germ cells and sperm FEBS Letters, 563, 87-92.
M'Barek,S. Lopez-Gonzalez,I. Andreotti,N. di Luccio,E. Visan,V. Grissmer,S. Judge,S. El Ayeb,M. Darbon,H. Rochat,H. Sampieri,F. Beraud,E. Fajloun,Z. De Waard,M. Sabatier,J.M.
2003. A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels Journal of Biological Chemistry, 278, 31095-31104 * .
Lopez-Gonzalez,I. Olamendi-Portugal,T. de la Vega-Beltran,J.L. van der Walt,J. Dyason,K. Possani,L.D. Felix,R. Darszon,A.
2003. Scorpion toxins that block T-type Ca(2+) channels in spermatogenic cells inhibit the sperm acrosome reaction Biochemical and Biophysical Research Communications, 300, 408-414.
Olamendi-Portugal,T. Garcia,B.I. Lopez-Gonzalez,I. van der Walt,J. Dyason,K. Ulens,C. Tytgat,J. Felix,R. Darszon,A. Possani,L.D.
2002. Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels Biochemical and Biophysical Research Communications, 299, 562-568.
Lopez-Gonzalez,I. de la Vega-Beltran,J.L. Santi,C.M. Florman,H.M. Felix,R. Darszon,A.
2001. Calmodulin antagonists inhibit t-type ca(2+) currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction Developmental Biology, 236, 210-219.
Espinosa,F. Lopez-Gonzalez,I. Munoz-Garay,C. Felix,R. de la Vega-Beltran,J.L. Kopf,G.S. Visconti,P.E. Darszon,A.
2000. Dual regulation of the T-type Ca(2+) current by serum albumin and beta-estradiol in mammalian spermatogenic cells FEBS Letters, 475, 251-256.
Espinosa,F. Lopez-Gonzalez,I. Serrano,C.J. Gasque,G. de la Vega-Beltran,J.L. Trevino,C.L. Darszon,A.
1999. 3.0.CO;2-B> Anion channel blockers differentially affect T-type Ca(2+) currents of mouse spermatogenic cells, alpha1E currents expressed in Xenopus oocytes and the sperm acrosome reaction Developmental Genetics, 25, 103-114.
Darszon,A. Espinoza,F. Santi,C. Lievano,A. Lopez,I. de la Vega-Beltran,J.L. Delgado,R. Labarca,P. Hernandez,A.
1998. Ca 2+ and Cl.Zygote, 6, S22-S23.
Espinosa,F. de la Vega-Beltran,J.L. Lopez-Gonzalez,I. Delgado,R. Labarca,P. Darszon,A.
1998. Mouse sperm patch-clamp recordings reveal single Cl- channels sensitive to niflumic acid, a blocker of the sperm acrosome reaction FEBS Letters, 426, 47-51.
Reyes,J.G. Sanchez-Cardenas,C. Acevedo-Castillo,W. Leyton,P. Lopez-Gonzalez,I. Felix,R. Gandini,M.A. Trevino,M.B. Trevino,C.L. 2014. Maitotoxin: An Enigmatic Toxic Molecule with Useful Applications in the Biomedical Sciences en: Botana,L.M. Seafood and Freshwater Toxins. Pharmacology, Physiology, and Detection. Boca Raton. CRC Press. pags. 677-694
Felix,R. Lopez-Gonzalez,I. Munoz-Garay,C. Darszon,A. 2004. Ion channels and sperm function en: Maue,R.A. Molecular Insights into Ion Channel Biology in Health and Disease. Elsevier. pags. 407-431
Darszon,A. Lopez,I. Trevino,C.L. 2003. Diálogo entre el espermatozoide y el óvulo en: Martínez-Palomo A Fronteras de la Biología en los Inicios del Siglo XXI, Biología Celular, Genética Molecular y Biotecnología, Módulo II.. Mexico,D.F.. El Colegio Nacional. pags. 33-55
Otras Publicaciones Garza-Lopez,E. Aldana,A. Darszon,A. Nishigaki,T. Lopez-Gonzalez,I.
2019. CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in their domains I/II bioRxiv, Preprint posted May 02, 2019, 626069.
Bondarenko,O. Corzo,G. Santana,F.L. del Rio-Portilla,F. Darszon,A. Lopez-Gonzalez,I.
2019. Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca2+ currents bioRxiv, Preprint posted March 23, 2019. [Publicado Febs Letters 2019], 586297.
* Indica publicación con otra institución de adscripción
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