![]() | Dr. Eduardo Horjales Reboredo Teléfonos |
- Licenciatura: Física, Universidad de la Republica de Uruguay, Fac. de Humanidades y Ciencias, Uruguay (1977)
- Doctorado: en Biología Molecular, Instituto de Biología Molecular, Suecia (1985)
Diaz,A. Valdes,V.J. Rudino-Pinera,E. Horjales,E. Hansberg,W.
2009. Structure-Function Relationships in Fungal Large-Subunit Catalases Journal of Molecular Biology, 386, 218-232.
Gonzalez-Segura,L. Rudino-Pinera,E. Munoz-Clares,R.A. Horjales,E.
2009. The Crystal Structure of A Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa Provides New Insight into the Reaction Mechanism and Shows A Novel Binding Mode of the 2'-Phosphate of NADP(+) and A Novel Cation Binding Site Journal of Molecular Biology, 385, 542-557.
Pazos,F. Valle,A. Martinez,D. Ramirez,A. Calderon,L. Pupo,A. Tejuca,M. Morera,V. Campos,J. Fando,R. Dyszy,F. Schreier,S. Horjales,E. Alvarez,C. Lanio,M.E. Lissi,E.
2006. Structural and functional characterization of a recombinant sticholysin I (rSt I) from the sea anemone Stichodactyla helianthus Toxicon, 48, 1083-1094.
Chavez-Gutierrez,L. Matta-Camacho,E. Osuna,J. Horjales,E. Joseph-Bravo,P. Maigret,B. Charli,J.L.
2006. Homology modeling and site directed mutagenesis of pyroglutamyl peptidase II. Insights into omega versus aminopeptidase specificity in the M1 family Journal of Biological Chemistry, 281, 18581-18590.
Diaz,A. Horjales,E. Rudino-Pinera,E. Arreola,R. Hansberg,W.
2004. Unusual cys-tyr covalent bond in a large catalase Journal of Molecular Biology, 342, 971-985.
Selisko,B. Cosio,G. Garcia,C. Becerril,B. Possani,L.D. Horjales,E.
2004. Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann Toxicon, 43, 43-51.
Arreola,R. Valderrama,B. Morante,M.L. Horjales,E.
2003. Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study FEBS Letters, 551, 63-70.
Ayala,M. Horjales,E. Pickard,M.A. Vazquez-Duhalt,R.
2002. Cross-linked crystals of chloroperoxidase Biochemical and Biophysical Research Communications, 295, 828-831.
Bustos-Jaimes,I. Sosa-Peinado,A. Rudino-Pinera,E. Horjales,E. Calcagno,M.L.
2002. On the Role of the Conformational Flexibility of the Active-site Lid on the Allosteric Kinetics of Glucosamine-6-phosphate Deaminase Journal of Molecular Biology, 319, 183-189 (Correction vol 322 (4) p 903.
Rudino-Pinera,E. Morales-Arrieta,S. Rojas-Trejo,S.P. Horjales,E.
2002. Structural flexibility, an essential component of the allosteric activation in Escherichia coli glucosamine-6-phosphate deaminase Acta Crystallographica Section D: Biological Crystallography, 58, 10-20.
Peter,M.J. Varga,Z. Hajdu,P. Gaspar,R. Damjanovich,S. Horjales,E. Possani,L.D. Panyi,G.
2001. Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24 Journal of Membrane Biology, 179, 13-25.
Selisko,B. Licea,A.F. Becerril,B. Zamudio,F. Possani,L.D. Horjales,E.
1999. 3.0.CO;2-S> Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen Proteins, 37, 130-143.
Horjales,E. Altamirano,M.M. Calcagno,M.L. Garratt,R.C. Oliva,G.
1999. The allosteric transition of glucosamine-6-phosphate deaminase: the structure of the T state at 2.3 A resolution Structure Fold.Des, 7, 527-537.
Montero-Moran,G.M. Horjales,E. Calcagno,M.L. Altamirano,M.M.
1998. Tyr254 hydroxyl group acts as a two-way switch mechanism in the coupling of heterotropic and homotropic effects in Escherichia coli glucosamine-6-phosphate deaminase Biochemistry, 37, 7844-7849.
Altamirano,M.M. Plumbridge,J.A. Horjales,E. Calcagno,M.L.
1995. Asymmetric allosteric activation of Escherichia coli glucosamine-6-phosphate deaminase produced by replacements of Tyr 121 Biochemistry, 34, 6074-6082 * .
Oliva,G. Fontes,M.R. Garratt,R.C. Altamirano,M.M. Calcagno,M.L. Horjales,E.
1995. Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution Structure, 3, 1323-1332 * .
Almagro,J.C. Vargas-Madrazo,E. Lara-Ochoa,F. Horjales,E.
1995. Molecular modeling of a T-cell receptor bound to a major histocompatibility complex molecule: implications for T-cell recognition Protein Science, 4, 1708-1717 * .
Horjales,E. Altamirano,M.M. Calcagno,M.L. Dauter,Z. Wilson,K. Garratt,R.C. Oliva,G.
1992. Crystallization and preliminary crystallographic studies of glucosamine-6-phosphate deaminase from Escherichia coli K12 Journal of Molecular Biology, 226, 1283-1286 * .
Eklund,H. Muller-Wille,P. Horjales,E. Futer,O. Holmquist,B. Vallee,B.L. Hoog,J.O. Kaiser,R. Jornvall,H.
1990. Comparison of three classes of human liver alcohol dehydrogenase. Emphasis on different substrate binding pockets European Journal of Biochemistry, 193, 303-310 * .
Eklund,H. Horjales,E. Vallee,B.L. Jornvall,H.
1987. Computer-graphics interpretations of residue exchanges between the alpha, beta and gamma subunits of human-liver alcohol dehydrogenase class I isozymes European Journal of Biochemistry, 167, 185-193 * .
Horjales,E. Eklund,H. Branden,C.I.
1987. Comparison of computer modelling and X-ray results of the binding of a pyrazole derivative to liver alcohol dehydrogenase Journal of Molecular Biology, 197, 685-694 * .
Horjales,E. Aqvist,J. Leijonmarck,M. Tapia,O.
1987. Aspects of model building applied to the C-terminal domain of the L12 protein from chloroplast ribosomes: a molecular dynamics study Biochemical and Biophysical Research Communications, 148, 954-961 * .
Cambillau,C. Horjales,E.
1987. TOM: a FRODO subpackage for protein-ligand fitting with interactive energy minimization Journal Of Molecular Graphics, 5, 174-177 * .
Horjales,E. Branden,C.I.
1985. Docking of cyclohexanol-derivatives into the active site of liver alcohol dehydrogenase. Using computer graphics and energy minimization Journal of Biological Chemistry, 260, 15445-15451 * .
Eklund,H. Horjales,E. Jornvall,H. Branden,C.I. Jeffery,J.
1985. Molecular aspects of functional differences between alcohol and sorbitol dehydrogenases Biochemistry, 24, 8005-8012 * .
Horjales,E. Gonzalez,L. Rudino-Pinera,E. Velasco,R. Munoz-Clares,R.A. 2005. Estructura de la Betaina Aldehido deshidrogenasa de Pseudonomas aeruginosa en: Sociedad Mexicana de Cristalografía A.C Cristalografia: fundamentos, tecnicos y investigaciones. pags. 75-78
Horjales,E.
1999. Expanding the atomic description of biological systems Nature Biotechnology, 17, 1068-1069.
* Indica publicación con otra institución de adscripción