IBT-UNAM : M. en C. Georgina Teresa Hernandez Chavez
M. en C. Georgina Teresa Hernandez Chavez
Grupo del Dr. Guillermo Gosset
Teléfonos
Oficina +52 (777) 311-4900 ext 217 Laboratorio +52 (777) 329-1601 red UNAM 27601 +52 (777) 311-4900 ext 217
Estudiantes Biol. Jessica Liliana Franco
Publicaciones recientes
Fragoso-Jimenez,J.C. Baert,J. Nguyen,T.M. Liu,W. Sassi,H. Goormaghtigh,F. Van Melderen L. Gaytan,P. Hernandez-Chavez,G. Martinez,A. Delvigne,F. Gosset,G.
2019. Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity Microbial Cell Factories, 18, 26.
Hernandez-Chavez,G. Martinez,A. Gosset,G.
2019. Metabolic engineering strategies for caffeic acid production in Escherichia coli Electronic Journal of Biotechnology, 38, 19-26.
Salas-Navarrete,C. Hernandez-Chavez,G. Flores,N. Martinez,L.M. Martinez,A. Bolivar,F. Barona-Gomez,F. Gosset,G.
2018. Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl carrier protein reductase Electronic Journal of Biotechnology, 33, 11-16.
Huerta-Beristain,G. Cabrera-Ruiz,R. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2017. Metabolic engineering and adaptive evolution of Escherichia coli KO11 for ethanol production through the Entner-Doudoroff and the pentose phosphate pathways Journal of Chemical Technology and Biotechnology, 92, 990-996.
Garcia,S. Flores,N. de Anda,R. Hernandez,G. Gosset,G. Bolivar,F. Escalante,A.
2017. The Role of the ydiB Gene, Which Encodes Quinate/Shikimate Dehydrogenase, in the Production of Quinic, Dehydroshikimic and Shikimic Acids in a PTS- Strain of Escherichia coli Journal of Molecular Microbiology and Biotechnology, 27, 11-21.
Camacho-Zaragoza,J.M. Hernandez-Chavez,G. Moreno-Avitia,F. Ramirez-Iniguez,R. Martinez,A. Bolivar,F. Gosset,G.
2016. Engineering of a microbial coculture of Escherichia coli strains for the biosynthesis of resveratrol Microbial Cell Factories, 15, 163.
Mejia-Caballero,A. de Anda,R. Hernandez-Chavez,G. Rogg,S. Martinez,A. Bolivar,F. Castano,V.M. Gosset,G.
2016. Biosynthesis of catechol melanin from glycerol employing metabolically engineered Escherichia coli Microbial Cell Factories, 15, 161.
Vargas-Tah,A. Martinez,L. Hernandez-Chavez,G. Rocha,M. Martinez,A. Bolivar,F. Gosset,G.
2015. Production of cinnamic and p -hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli Microbial Cell Factories, 14, 6.
Balderas-Hernandez,V.E. Trevino-Quintanilla,L.G. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2014. Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1 Microbial Cell Factories, 13, 136.
Sabido,A. Sigala,J.C. Hernandez-Chavez,G. Flores,N. Gosset,G. Bolivar,F.
2014. Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized Biotechnology and Bioengineering, 111, 1150-1160.
Licona-Cassani,C. Lara,A.R. Cabrera-Valladares,N. Escalante,A. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2014. Inactivation of Pyruvate Kinase or the Phosphoenolpyruvate: Sugar Phosphotransferase System Increases Shikimic and Dehydroshikimic Acid Yields from Glucose in Bacillus subtilis Journal of Molecular Microbiology and Biotechnology, 24, 37-45.
Rodriguez,A. Martinez,J.A. Baez-Viveros,J.L. Flores,N. Hernandez-Chavez,G. Ramirez,O.T. Gosset,G. Bolivar,F.
2013. Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykF Microbial Cell Factories, 12, 86.
Cabrera-Valladares,N. Martinez,L.M. Flores,N. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2012. Physiologic Consequences of Glucose Transport and Phosphoenolpyruvate Node Modifications in Bacillus subtilis 168 Journal of Molecular Microbiology and Biotechnology, 22, 177-197.
Martinez-Gomez,K. Flores,N. Castaneda,H.M. Martinez-Batallar,G. Hernandez-Chavez,G. Ramirez,O.T. Gosset,G. Encarnacion,S. Bolivar,F.
2012. New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during growth on glycerol Microbial Cell Factories, 11, 46.
Munoz,A.J. Hernandez-Chavez,G. de Anda,R. Martinez,A. Bolivar,F. Gosset,G.
2011. Metabolic engineering of Escherichia coli for improving L: -3,4-dihydroxyphenylalanine (L: -DOPA) synthesis from glucose Journal of Industrial Microbiology & Biotechnology, 38, 1845-1852.
Escalante,A. Calderon,R. Valdivia,A. de Anda,R. Hernandez,G. Ramirez,O.T. Gosset,G. Bolivar,F.
2010. Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system Microbial Cell Factories, 9, 21.
Balderas-Hernandez,V.E. Sabido-Ramos,A. Silva,P. Cabrera-Valladares,N. Hernandez-Chavez,G. Baez-Viveros,J.L. Martinez,A. Bolivar,F. Gosset,G.
2009. Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli Microbial Cell Factories, 8, 19.
Orencio-Trejo,M. Flores,N. Escalante,A. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2008. Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities Biotechnology for Biofuels, 1, 8.
Escalante,A. Giles-Gomez,M. Hernandez,G. Cordova-Aguilar,M.S. Lopez-Munguia,A. Gosset,G. Bolivar,F.
2008. Analysis of bacterial community during the fermentation of pulque, a traditional Mexican alcoholic beverage, using a polyphasic approach International Journal of Food Microbiology, 124, 126-134.
Huerta-Beristain,G. Utrilla,J. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2008. Specific ethanol production rate in ethanologenic Escherichia coli strain KO11 Is limited by pyruvate decarboxylase Journal of Molecular Microbiology and Biotechnology, 15, 55-64.
Chavez-Bejar,M.I. Lara,A.R. Lopez,H. Hernandez-Chavez,G. Martinez,A. Ramirez,O.T. Bolivar,F. Gosset,G.
2008. Metabolic engineering of Escherichia coli for L-tyrosine production by the expression of the genes coding for the chorismate mutase domain from native P-protein and a cyclohexadienyl dehydrogenase from Zymomonas mobilis Applied and Environmental Microbiology, 74, 3284-3290.
Martinez,K. de Anda,R. Hernandez,G. Escalante,A. Gosset,G. Ramirez,O.T. Bolivar,F.G.
2008. Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system Microbial Cell Factories, 7, 1.
Flores,N. de Anda,R. Flores,S. Escalante,A. Hernandez,G. Martinez,A. Ramirez,O.T. Gosset,G. Bolivar,F.
2004. Role of Pyruvate Oxidase in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Journal of Molecular Microbiology and Biotechnology, 8, 209-221.
Baez-Viveros,J.L. Osuna,J. Hernandez-Chavez,G. Soberon,X. Bolivar,F. Gosset,G.
2004. Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli Biotechnology and Bioengineering, 87, 516-524.
Palmeros,B. Wild,J. Szybalski,W. Le Borgne,S. Hernandez-Chavez,G. Gosset,G. Valle,F. Bolivar,F.
2000. A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria Gene, 247, 255-264.
Cruz,N. Le Borgne,S. Hernandez-Chavez,G. Gosset,G. Valle,F. Bolivar,F.
2000. Engineering the Escherichia coli outer membrane protein OmpC for metal bioadsorption Biotechnology Letters, 22, 623-629.
Siguenza,R. Flores,N. Hernandez,G. Martinez,A. Bolivar,F. Valle,F.
1999. Kinetic characterization in batch and continuous culture of Escherichia coli mutants affected in phosphoenolpyruvate metabolism: differences in acetic acid production World Journal Of Microbiology & Biotechnology, 15, 587-592.
Otras Publicaciones Baez-Viveros,J.L. Osuna,J. Hernandez-Chavez,G. Soberon,X. Bolivar,F. Gosset,G.
2006. Metabolic via engineering for the production of aromatic substances in Escherichia coli Revista Latinoamericana de Microbiologia, 48, 92.
Huerta-Beristain,G. Utrilla,J. Hernandez-Chavez,G. Bolivar,F. Martinez,A.
2005. Ingenieria metabolica para incrementar el flux y rendimientos de etanol en Escherischia coli etanologenica Revista Mexicana de Ingenieria Quimica, 4, 25-36.
Patentes José Manuel Camacho Zaragoza, Georgina Teresa Hernández Chávez, Fabián Moreno Avitia, René Ramírez Iñiguez, Alfredo Martínez Jiménez , Francisco Bolívar Zapata, Guillermo Gosset Lagarda 2017 Cepas de Escherichia coli modificadas por ingeniería de vías metabólicas para la biosíntesis de resveratrol y su uso en un nuevo proceso de co-cultivo.UNAM México. (en trámite)
Alfredo Martínez Jiménez, Guillermo Gosset Lagarda, Luz María Martínez Mejía, Georgina Teresa Hernández Chávez, Mauricio García Benítez 2016 Cepas de Escherichia coli modificadas por ingeniería metabólica para la producción de (R)-3-hidroxibutirato.UNAM México. (en trámite)
A. Martínez J. G. Gosset L. G. T. Hernández Ch. G. Huerta B. B. Trujillo y M., J. Utrilla C. 2013 Strains of Escherichia coli modified by metabolic engineering to produce chemical compounds from hydrolyzed lignocellulose, pentoses, hexoses or other carbon sources.UNAM EUA 8563283, México No. 31474 y 3127021.
Guillermo Gosset Lagarda , Alfredo Martínez Jiménez , Francisco Gonzalo Bolívar Zapata , Ana Joyce Muñoz Arellano, Georgina Teresa Hernández Chávez y Ramón de Anda Herrera 2011 Cepas de Escherichia coli modificadas para producir 3,4-hidroxi-L-fenilalanina (L-Dopa).UNAM México. (en trámite)
J. Osuna, J.L. Báez, G. Hernández, F. G. Bolivar, X. Soberón y G. Gosset 2005 Versiones insensibles a inhibición alostérica y catalíticamente eficientes de la enzima corismato mutasa-prefenato deshidratasa y su aplicación para la producción de L-fenilalanina en microorganismos.
Técnico Académico