. Instituto de Biotecnologia UNAM

IBT-UNAM : Dra. Elda Guadalupe Espin Ocampo

Dra. Elda Guadalupe Espin Ocampo

Jefe del Departamento Microbiología Molecular
Líder Académico »» Grupo
Investigador
Tutor de Maestría y Doctorado
Nivel III del SNI
Líneas de investigación

email: espin @ibt.unam.mx
Teléfonos

Oficina +52 (777) 329-1644
desde la CDMX 562-27644
red UNAM 27644
+52 (777) 311-4900 ext 236

Laboratorio +52 (777) 329-1629
desde la CDMX 562-27629
red UNAM 27629
+52 (777) 311-4900 ext 236

- Licenciatura: Biología, Universidad Autonoma de Morelos (1976)
- Maestría: en Investigacion Biomedica Basica, Instituto de Investigaciones Biomedicas-UNAM (1978)
- Doctorado: en Investigacion Biomedica Basica, Instituto de Investigaciones Biomedicas-UNAM (1992)
- Mencion honorífica en el examen del grado de Maestría
- Estancia de Investigación: Unit of Nitrogen Fixation University of Sussex Inglaterra (dic 78-marzo 80)
- Estancia de Investigación: Fakultat Biologie Universidad de Bielefel Alemania Ene-marzo 1985
- Estancia de Investigación: Istituto Internazionale di Genetica e Biofisica CNR Napoles Italia jun 88-jun89

Medalla de Honor en la Categoria Aportaciones a la Ciencia Congreso del Estado de Morelos (2012)
Distinción Sor Juana Inés de la Cruz UNAM (2005)

Estudiantes

M.C. Guillermina Sánchez

Ana Karen Jaimes "Estudio del control transcripcional del gen crc que codifica un regulador del proceso de represión catabólica en azotobacter vinelandii."

Biol. Mariana López

Biol. Karen Ameyally Rodríguez

Biol. Alan David Jiménez

M.C. Juliana Berenice Rojo

M.C. Adan Trejo

M.C. Cristian Camilo Ortiz

Ing. Ricardo Javier Farrera

Biol. José Pablo Olache

Publicaciones recientes

Martinez-Ortiz,I.C. Ahumada-Manuel,C.L. Hsueh,B.Y. Guzman,J. Moreno,S. Cocotl-Yanez,M. Waters,C.M. Zamorano-Sanchez,D. Espin,G. Nunez,C. 2020. Cyclic di-GMP-Mediated Regulation of Extracellular Mannuronan C-5 Epimerases Is Essential for Cyst Formation in Azotobacter vinelandii Journal of Bacteriology, 202, e00135-20.

Ahumada-Manuel,C.L. Martinez-Ortiz,I.C. Hsueh,B.Y. Guzman,J. Waters,C.M. Zamorano-Sanchez,D. Espin,G. Nunez,C. 2020. Increased c-di-GMP Levels Lead to the Production of Alginates of High Molecular Mass in Azotobacter vinelandii Journal of Bacteriology, 202, e00134-20.

Velazquez-Sanchez,C. Espin,G. Pena,C. Segura,D. 2020. The Modification of Regulatory Circuits Involved in the Control of Polyhydroxyalkanoates Metabolism to Improve Their Production Frontiers in Bioengineering and Biotechnology, 8, 386.

Millan,C. Pena,C. Flores,C. Espin,G. Galindo,E. Castillo,T. 2020. Improving glucose and xylose assimilation in Azotobacter vinelandii by adaptive laboratory evolution World Journal Of Microbiology & Biotechnology, 36, 46.

Moreno,S. Castellanos,M. Bedoya-Perez,L.P. Canales-Herrerias,P. Espin,G. Muriel-Millan,L.F. 2019. Outer membrane protein I is associated with poly-beta-hydroxybutyrate granules and is necessary for optimal polymer accumulation in Azotobacter vinelandii on solid medium Microbiology, 165, 1107-1116.

Garcia,A. Perez,D. Castro,M. Urtuvia,V. Castillo,T. Diaz-Barrera,A. Espin,G. Pena,C. 2019. Production and recovery of poly-3-hydroxybutyrate (P(3HB)) of ultra-high molecular weight using fed-batch cultures of Azotobacter vinelandii OPNA strain Journal of Chemical Technology & Biotechnology, 94, 1853-1860.

Martinez-Valenzuela,M. Guzman,J. Moreno,S. Ahumada-Manuel,C.L. Espin,G. Nunez,C. 2018. Expression of the sRNAs CrcZ and CrcY modulate the strength of carbon catabolite repression under diazotrophic or non-diazotrophic growing conditions in Azotobacter vinelandii PLoS ONE, 13, e0208975.

Moreno,S. Ertesvag,H. Valla,S. Nunez,C. Espin,G. Cocotl-Yanez,M. 2018. RpoS controls the expression and the transport of the AlgE1-7 epimerases in Azotobacter vinelandii Fems Microbiology Letters, 365, fny210.

Bedoya-Perez,L.P. Muriel-Millan,L.F. Moreno,S. Quiroz-Rocha,E. Rivera-Gomez,N. Espin,G. 2018. The pyrophosphohydrolase RppH is involved in the control of RsmA/CsrA expression in Azotobacter vinelandii and Escherichia coli Microbiological Research, 214, 91-100.

Chowdhury-Paul,S. Pando-Robles,V. Jimenez-Jacinto,V. Segura,D. Espin,G. Nunez,C. 2018. Proteomic analysis revealed proteins induced upon Azotobacter vinelandii encystment Journal of Proteomics, 181, 47-59.

Adaya,L. Millan,M. Pena,C. Jendrossek,D. Espin,G. Tinoco-Valencia,R. Guzman,J. Pfeiffer,D. Segura,D. 2018. Inactivation of an intracellular poly-3-hydroxybutyrate depolymerase of Azotobacter vinelandii allows to obtain a polymer of uniform high molecular mass Applied Microbiology and Biotechnology, 102, 2693-2707.

Cruz-Rabadan,J.S. Miranda-Rios,J. Espin-Ocampo,G. Mendez-Tovar,L.J. Maya-Pineda,H.R. Hernandez-Hernandez,F. 2017. Non-coding RNAs are differentially expressed by Nocardia brasiliensis in vitro and in experimental actinomycetoma Open Microbiology Journal, 11, 112-125.

Quiroz-Rocha,E. Bonilla-Badia,F. Garcia-Aguilar,V. Lopez-Pliego,L. Serrano-Roman,J. Cocotl-Yanez,M. Guzman,J. Ahumada-Manuel,C.L. Muriel-Millan,L.F. Castaneda,M. Espin,G. Nunez,C. 2017. Two-component system CbrA/CbrB controls alginate production in Azotobacter vinelandii Microbiology, 163, 1105-1115.

Quiroz-Rocha,E. Moreno,R. Hernandez-Ortiz,A. Fragoso-Jimenez,J.C. Muriel-Millan,L.F. Guzman,J. Espin,G. Rojo,F. Nunez,C. 2017. Glucose uptake in Azotobacter vinelandii occurs through a GluP transporter that is under the control of the CbrA/CbrB and Hfq-Crc systems Scientific Reports, 7, 858.

Castillo,T. Flores,C. Segura,D. Espin,G. Sanguino,J. Cabrera,E. Barreto,J. Diaz-Barrera,A. Pena,C. 2017. Production of polyhydroxybutyrate (PHB) of high and ultra-high molecular weight by Azotobacter vinelandii in batch and fed-batch cultures Journal of Chemical Technology & Biotechnology, 92, 1809-1816.

Rodriguez-Salazar,J. Moreno,S. Espin,G. 2017. LEA proteins are involved in cyst desiccation resistance and other abiotic stresses in Azotobacter vinelandii Cell Stress and Chaperones, 22, 397-408.

Muriel-Millan,L.F. Moreno,S. Gallegos-Monterrosa,R. Espin,G. 2017. Unphosphorylated EIIANtr induces ClpAP-mediated degradation of RpoS in Azotobacter vinelandii Molecular Microbiology, 104, 197-211.

Trejo,A. Moreno,S. Cocotl-Yanez,M. Espin,G. 2017. GacA regulates the PTSNtr-dependent control of cyst formation in Azotobacter vinelandii Fems Microbiology Letters, 364, fnw278.

Ahumada-Manuel,C.L. Guzman,J. Pena,C. Quiroz-Rocha,E. Espin,G. Nunez,C. 2017. The signaling protein MucG negatively affects the production and the molecular mass of alginate in Azotobacter vinelandii Applied Microbiology and Biotechnology, 101, 1521-1534.

Romero,Y. Guzman,J. Moreno,S. Cocotl-Yanez,M. Vences-Guzman,M.A. Castaneda,M. Espin,G. Segura,D. 2016. The GacS/A-RsmA Signal Transduction Pathway Controls the Synthesis of Alkylresorcinol Lipids that Replace Membrane Phospholipids during Encystment of Azotobacter vinelandii SW136 PLoS ONE, 11, e0153266.

Muriel-Millan,L.F. Moreno,S. Romero,Y. Bedoya-Perez,L.P. Castaneda,M. Segura,D. Espin,G. 2015. The Unphosphorylated EIIANtr Protein Represses the Synthesis of Alkylresorcinols in Azotobacter vinelandii PLoS ONE, 10, e0117184.

Dominguez-Diaz,M. Meneses-Acosta,A. Romo-Uribe,A. Pena,C. Segura,D. Espin,G. 2015. Thermo-mechanical properties, microstructure and biocompatibility in poly-beta-hydroxybutyrates (PHB) produced by OP and OPN strains of Azotobacter vinelandii European Polymer Journal, 63, 101-112.

Catone,M.V. Ruiz,J.A. Castellanos,M. Segura,D. Espin,G. Lopez,N.I. 2014. High Polyhydroxybutyrate Production in Pseudomonas extremaustralis Is Associated with Differential Expression of Horizontally Acquired and Core Genome Polyhydroxyalkanoate Synthase Genes PLoS ONE, 9, e98873.

Gonzalez-Casanova,A. Aguirre-von-Wobeser,E. Espin,G. Servin-Gonzalez,L. Kurt,N. Spano,D. Blath,J. Soberon-Chavez,G. 2014. Strong seed-bank effects in bacterial evolution Journal of Theoretical Biology, 356, 62-70.

Cocotl-Yanez,M. Moreno,S. Encarnacion,S. Lopez-Pliego,L. Castaneda,M. Espin,G. 2014. A small heat shock protein (Hsp20) regulated by RpoS is essential for cyst desiccation resistance in Azotobacter vinelandii Microbiology, 160, 479-487.

Garcia,A. Segura,D. Espin,G. Galindo,E. Castillo,T. Pena,C. 2014. High production of poly-beta-hydroxybutyrate (PHB) by an Azotobacter vinelandii mutant altered in PHB regulation using a fed-batch fermentation process Biochemical Engineering Journal, 82, 117-123.

Muriel-Millan,L.F. Castellanos,M. Hernandez-Eligio,J.A. Moreno,S. Espin,G. 2014. Posttranscriptional regulation of PhbR, the transcriptional activator of polyhydroxybutyrate synthesis, by iron and the sRNA ArrF in Azotobacter vinelandii Applied Microbiology and Biotechnology, 98, 2173-2182.

Pena,C. Lopez,S. Garcia,A. Espin,G. Romo-Uribe,A. Segura,D. 2014. Biosynthesis of poly-b-hydroxybutyrate (PHB) with a high molecular mass by a mutant strain of Azotobacter vinelandii (OPN) Annals of Microbiology, 64, 39-47.

Flores,C. Moreno,S. Espin,G. Pena,C. Galindo,E. 2013. Expression of alginases and alginate polymerase genes in response to oxygen, and their relationship with the alginate molecular weight in Azotobacter vinelandii Enzyme and Microbial Technology, 53, 85-91.

Romero,Y. Moreno,S. Guzman,J. Espin,G. Segura,D. 2013. The Sigma Factor RpoS Controls Alkylresorcinol Synthesis Through ArpR, a LysR-Type Regulatory Protein During Encystment of Azotobacter vinelandii Journal of Bacteriology, 195, 1834-1844.

Nunez,C. Pena,C. Kloeckner,W. Hernandez-Eligio,A. Bogachev,A.V. Moreno,S. Guzman,J. Buchs,J. Espin,G. 2013. Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone Applied Microbiology and Biotechnology, 97, 2503-2512.

Gaytan,I. Pena,C. Nunez,C. Cordova,M.S. Espin,G. Galindo,E. 2012. Azotobacter vinelandii lacking the Na +-NQR activity: a potential source for producing alginates with improved properties and at high yield World Journal Of Microbiology & Biotechnology, 28, 2731-2740.

Hernandez-Eligio,A. Moreno,S. Castellanos,M. Castaneda,M. Nunez,C. Muriel-Millan,L.F. Espin,G. 2012. RsmA post-transcriptionally controls PhbR expression and polyhydroxybutyrate biosynthesis in Azotobacter vinelandii Microbiology, 158, 1953-1963.

Manzo,J. Cocotl-Yanez,M. Tzontecomani,T. Martinez,V.M. Bustillos,R. Velasquez,C. Goiz,Y. Solis,Y. Lopez,L. Fuentes,L.E. Nunez,C. Segura,D. Espin,G. Castaneda,M. 2011. Post-Transcriptional Regulation of the Alginate Biosynthetic Gene algD by the Gac/Rsm System in Azotobacter vinelandii Journal of Molecular Microbiology and Biotechnology, 21, 147-159.

Hernandez-Eligio,A. Castellanos,M. Moreno,S. Espin,G. 2011. Transcriptional activation of the Azotobacter vinelandii polyhydroxybutyrate biosynthetic genes phbBAC by PhbR and RpoS Microbiology, 157, 3014-3023.

Cocotl-Yanez,M. Sampieri,A. Moreno,S. Nunez,C. Castaneda,M. Segura,D. Espin,G. 2011. Roles of RpoS and PsrA in cyst formation and alkylresorcinol synthesis in Azotobacter vinelandii Microbiology, 157, 1685-1693.

Mejia,M.A. Segura,D. Espin,G. Galindo,E. Pena,C. 2010. Two-stage fermentation process for alginate production by Azotobacter vinelandii mutant altered in poly-beta-hydroxybutyrate (PHB) synthesis Journal of Applied Microbiology, 108, 55-61.

Setubal,J.C. Dos Santos P. Goldman,B.S. Ertesvag,H. Espin,G. Rubio,L.M. Valla,S. Almeida,N.F. Balasubramanian,D. Cromes,L. Curatti,L. Du,Z. Godsy,E. Goodner,B. Hellner-Burris,K. Hernandez,J.A. Houmiel,K. Imperial,J. Kennedy,C. Larson,T.J. Latreille,P. Ligon,L.S. Lu,J. Maerk,M. Miller,N.M. Norton,S. O'Carroll,I.P. Paulsen,I. Raulfs,E.C. Roemer,R. Rosser,J. Segura,D. Slater,S. Stricklin,S.L. Studholme,D.J. Sun,J. Viana,C.J. Wallin,E. Wang,B. Wheeler,C. Zhu,H. Dean,D.R. Dixon,R. Wood,D. 2009. The genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes Journal of Bacteriology, 191, 4534-4545.

Segura,D. Vite,O. Romero,Y. Moreno,S. Castaneda,M. Espin,G. 2009. Isolation and Characterization of Azotobacter vinelandii Mutants Impaired in Alkylresorcinol Synthesis: Alkylresorcinols are not Essential for Cysts Desiccation Resistance Journal of Bacteriology, 191, 3142-3148.

Nunez,C. Bogachev,A.V. Guzman,G. Tello,I. Guzman,J. Espin,G. 2009. The Na+-translocating NADH : ubiquinone oxidoreductase of Azotobacter vinelandii negatively regulates alginate synthesis Microbiology, 155, 249-256.

Leon,R. Espin,G. 2008. flhDC, but not fleQ, regulates flagella biogenesis in Azotobacter vinelandii, and is under AlgU and CydR negative control Microbiology, 154, 1719-1728.

Steigedal,M. Sletta,H. Moreno,S. Maerk,M. Christensen,B.E. Bjerkan,T. Ellingsen,T.E. Espin,G. Ertesvag,H. Valla,S. 2008. The Azotobacter vinelandii AlgE mannuronan C-5-epimerase family is essential for the in vivo control of alginate monomer composition and for functional cyst formation Environmental Microbiology, 10, 1760-1770.

Fadeeva,M.S. Nunez,C. Bertsova,Y.V. Espin,G. Bogachev,A.V. 2008. Catalytic properties of Na+-translocating NADH : quinone oxidoreductases from Vibrio harveyi, Klebsiella pneumoniae, and Azotobacter vinelandii Fems Microbiology Letters, 279, 116-123.

Noguez,R. Segura,D. Moreno,S. Hernandez,A. Juarez,K. Espin,G. 2008. Enzyme I, NPr and IIA(Ntr) Are Involved in Regulation of the Poly-beta-Hydroxybutyrate Biosynthetic Genes in Azotobacter vinelandii Journal of Molecular Microbiology and Biotechnology, 15, 244-254.

Galindo,E. Pena,C. Nunez,C. Segura,D. Espin,G. 2007. Molecular and bioengineering strategies to improve alginate and polydydroxyalkanoate production by Azotobacter vinelandii Microbial Cell Factories, 6, 7.

Gimmestad,M. Steigedal,M. Ertesvag,H. Moreno,S. Christensen,B.E. Espin,G. Valla,S. 2006. Identification and Characterization of an Azotobacter vinelandii Type I Secretion System Responsible for Export of the AlgE-Type Mannuronan C-5-Epimerases Journal of Bacteriology, 188, 5551-5560.

Gaona,G. Nunez,C. Goldberg,J.B. Linford,A.S. Najera,R. Castaneda,M. Guzman,J. Espin,G. Soberon-Chavez,G. 2004. Characterization of the Azotobacter vinelandii algC gene involved in alginate and lipopolysaccharide production Fems Microbiology Letters, 238, 199-206.

Segura,D. Espin,G. 2004. Inactivation of pycA, encoding pyruvate carboxylase activity, increases poly-beta-hydroxybutyrate accumulation in Azotobacter vinelandii on solid medium Applied Microbiology and Biotechnology, 65, 414-418.

Trujillo-Roldan,M.A. Moreno,S. Espin,G. Galindo,E. 2004. The roles of oxygen and alginate-lyase in determining the molecular weight of alginate produced by Azotobacter vinelandii Applied Microbiology and Biotechnology, 63, 742-747.

Segura,D. Guzman,J. Espin,G. 2003. Azotobacter vinelandii mutants that overproduce poly-beta-hydroxybutyrate or alginate Applied Microbiology and Biotechnology, 63, 159-163.

Segura,D. Cruz,T. Espin,G. 2003. Encystment and alkylresorcinol production by Azotobacter vinelandii strains impaired in poly-beta-hydroxybutyrate synthesis Archives of Microbiology, 179, 437-443.

Trujillo-Roldan,M.A. Moreno,S. Segura,D. Galindo,E. Espin,G. 2003. Alginate production by an Azotobacter vinelandii mutant unable to produce alginate lyase Applied Microbiology and Biotechnology, 60, 733-737.

Pena,C. Miranda,L. Segura,D. Nunez,C. Espin,G. Galindo,E. 2002. Alginate production by Azotobacter vinelandii mutants altered in poly-beta-hydroxybutyrate and alginate biosynthesis Journal of Industrial Microbiology & Biotechnology, 29, 209-213.

Peralta-Gil,M. Segura,D. Guzman,J. Servin-Gonzalez,L. Espin,G. 2002. Expression of the Azotobacter vinelandii Poly-beta-Hydroxybutyrate Biosynthetic phbBAC Operon Is Driven by Two Overlapping Promoters and Is Dependent on the Transcriptional Activator PhbR Journal of Bacteriology, 184, 5672-5677.

Castaneda,M. Sanchez,J. Moreno,S. Nunez,C. Espin,G. 2001. The Global Regulators GacA and sigma(S) Form Part of a Cascade That Controls Alginate Production in Azotobacter vinelandii Journal of Bacteriology, 183, 6787-6793.

Gama-Castro,S. Nunez,C. Segura,D. Moreno,S. Guzman,J. Espin,G. 2001. Azotobacter vinelandii Aldehyde Dehydrogenase Regulated by sigma(54): Role in Alcohol Catabolism and Encystment Journal of Bacteriology, 183, 6169-6174.

Nunez,C. Moreno,S. Cardenas,L. Soberon-Chavez,G. Espin,G. 2000. Inactivation of the ampDE operon increases transcription of algD and affects morphology and encystment of Azotobacter vinelandii Journal of Bacteriology, 182, 4829-4835.

Nunez,C. Leon,R. Guzman,J. Espin,G. Soberon-Chavez,G. 2000. Role of Azotobacter vinelandii mucA and mucC gene products in alginate production Journal of Bacteriology, 182, 6550-6556.

Castaneda,M. Guzman,J. Moreno,S. Espin,G. 2000. The GacS sensor kinase regulates alginate and poly-beta-hydroxybutyrate production in Azotobacter vinelandii Journal of Bacteriology, 182, 2624-2628.

Segura,D. Vargas,E. Espin,G. 2000. Beta-ketothiolase genes in Azotobacter vinelandii Gene, 260, 113-120.

Nunez,C. Moreno,S. Soberon-Chavez,G. Espin,G. 1999. The Azotobacter vinelandii response regulator AlgR is essential for cyst formation Journal of Bacteriology, 181, 141-148.

Vazquez,A. Moreno,S. Guzman,J. Alvarado,A. Espin,G. 1999. Transcriptional organization of the Azotobacter vinelandii algGXLVIFA genes: characterization of algF mutants Gene, 232, 217-222.

Segura,D. Espin,G. 1998. Mutational inactivation of a gene homologous to Escherichia coli ptsP affects poly-beta-hydroxybutyrate accumulation and nitrogen fixation in Azotobacter vinelandii Journal of Bacteriology, 180, 4790-4798.

Moreno,S. Najera,R. Guzman,J. Soberon-Chavez,G. Espin,G. 1998. Role of alternative sigma factor algU in encystment of Azotobacter vinelandii Journal of Bacteriology, 180, 2766-2769.

Mejia-Ruiz,H. Guzman,J. Moreno,S. Soberon-Chavez,G. Espin,G. 1997. The Azotobacter vinelandii alg8 and alg44 genes are essential for alginate synthesis and can be transcribed from an algD-independent promoter Gene, 199, 271-277.

Mejia-Ruiz,H. Moreno,S. Guzman,J. Najera,R. Leon,R. Soberon-Chavez,G. Espin,G. 1997. Isolation and characterization of an Azotobacter vinelandii algK mutant Fems Microbiology Letters, 156, 101-106.

Martinez,P. Guzman,J. Espin,G. 1997. A mutation impairing alginate production increased accumulation of poly-beta-hydroxybutyrate in Azotobacter vinelandii Biotechnology Letters, 19, 909-911.

Campos,M. Martinez-Salazar,J.M. Lloret,L. Moreno,S. Nunez,C. Espin,G. Soberon-Chavez,G. 1996. Characterization of the gene coding for GDP-mannose dehydrogenase (algD) from Azotobacter vinelandii Journal of Bacteriology, 178, 1793-1799.

Lloret,L. Barreto,R. Leon,R. Moreno,S. Martinez-Salazar,J. Espin,G. Soberon-Chavez,G. 1996. Genetic analysis of the transcriptional arrangement of Azotobacter vinelandii alginate biosynthetic genes: identification of two independent promoters Molecular Microbiology, 21, 449-457.

Martinez-Salazar,J.M. Moreno,S. Najera,R. Boucher,J.C. Espin,G. Soberon-Chavez,G. Deretic,V. 1996. Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis Journal of Bacteriology, 178, 1800-1808.

Espin,G. Moreno,S. Guzman,J. 1994. Molecular genetics of the glutamine synthetases in Rhizobium species Critical Reviews in Microbiology, 20, 117-123.

Noguez,R. Moreno,S. Guzman,J. Espin,G. 1994. The effect of the nitrogen and ntrC on the adenylylation of glutamine synthetase I in Rhizobium etli Canadian Journal of Microbiology, 40, 965-968.

Chiurazzi,M. Meza,R. Lara,M. Lahm,A. Defez,R. Iaccarino,M. Espin,G. 1992. The Rhizobium-Leguminosarum Biovar Phaseoli Glnt Gene, Encoding Glutamine Synthetase-Iii Gene, 119, 1-8.

Moreno,S. Patriarca,E.J. Chiurazzi,M. Meza,R. Defez,R. Lamberti,A. Riccio,A. Iaccarino,M. Espin,G. 1992. Phenotype of a Rhizobium leguminosarum ntrC mutant Research in Microbiology, 143, 161-171 * .

Soberon-Chavez,G. Najera,R. Espin,G. Moreno,S. 1991. Formation of Rhizobium phaseoli symbiotic plasmids by genetic recombination Molecular Microbiology, 5, 909-916.

Moreno,S. Meza,R. Guzman,J. Carabez,A. Espin,G. 1991. The glnA Gene of Rhizobium leguminosarum bv. phaseoli and Its Role In Symbiosis Molecular Plant-Microbe Interactions, 4, 619-622.

Espin,G. Moreno,S. Wild,M. Meza,R. Iaccarino,M. 1990. A previously unrecognized glutamine synthetase expressed in Klebsiella pneumoniae from the glnT locus of Rhizobium leguminosarum Molecular and General Genetics, 223, 513-516 * .

Cevallos,M.A. Vazquez,M. Davalos,A. Espin,G. Sepulveda,J. Quinto,C. 1989. Characterization of Rhizobium phaseoli Sym plasmid regions involved in nodule morphogenesis and host-range specificity Molecular Microbiology, 3, 879-889 * .

Morett,E. Moreno,S. Espin,G. 1988. Transcription analysis of the three nifH genes of Rhizobium phaseoli with gene fusions MGG Molecular & General Genetics, 213, 499-504 * .

Morett,E. Moreno,S. Espin,G. 1985. Impaired nitrogen fixation and glutamine synthesis in methionine sulfoximine sensitive (MSs) mutants of Rhizobium phaseoli MGG Molecular & General Genetics, 200, 229-234 * .

Espin,G. Alvarez-Morales,A. Cannon,F. Dixon,R. Merrick,M. 1982. Cloning of the glnA, ntrB and ntrC genes of Klebsiella pneumoniae and studies of their role in regulation of the nitrogen fixation (nif) gene cluster MGG Molecular & General Genetics, 186, 518-524 * .

Espin,G. Alvarez-Morales,A. Merrick,M. 1981. Complementation analysis of glnA-linked mutations which affect nitrogen fixation in Klebsiella pneumoniae MGG Molecular & General Genetics, 184, 213-217 * .

Dixon,R. Eady,R.R. Espin,G. Hill,S. Iaccarino,M. Kahn,D. Merrick,M. 1980. Analysis of regulation of Klebsiella pneumoniae nitrogen fixation (nif) gene cluster with gene fusions Nature, 286, 128-132 * .

Hansberg,W. Espin,G. Palacios,R. Sanchez,F. 1979. Regulation of glutamine synthetase messenger ribonucleic acid in connidia of Neurospora crassa Developmental Biology, 73, 68-75 * .

Espin,G. Palacios,R. Mora,J. 1979. Glutamine metabolism in nitrogen-starved conidia of Neurospora crassa Journal of General Microbiology, 115, 59-68 * .

Mora,Y. Espin,G. Willms,K. Mora,J. 1978. Nitrogen accumulation in mycelium of Neurospora crassa Journal of General Microbiology, 104, 241-250 * .

Espin,G. Mora,J. 1978. EFFECT OF DEPRIVATION OF AMINO-ACIDS ON CONIDIA OF NEUROSPORA- CRASSA Journal of General Microbiology, 104, 233-240 * .

Libros y capítulos recientes

Segura,D. Nunez,C. Espin,G. 2020. Azotobacter Cysts en: eLS. Chichester, West Sussex. Editorial John Wiley & Sons.

Espin,G. 2016. Genes Involved in the Formation of Desiccation- Resistant Cysts in Azotobacter Vinelandii en: de Bruijn,F.J. Stress and Environmental Control of Gene Expression in Bacteria. Wiley-Blackwell. pags. 709-715

Castaneda,M. Lopez-Pliego,L. Espin,G. 2016. Azotobacter vinelandii Small RNAs: Their Roles in the Formation of CystsCyst and Other Processes en: Enguita,F.J. Non-coding RNAs and Inter-kingdom Communication. Cham. Springer International Publishing. pags. 67-82

Segura,D. Nunez,C. Espin,G. 2014. Azotobacter Cysts en: Encyclopedia of Life Science. Chichester, West Sussex. Editorial John Wiley & Sons.

Romero,Y. Pena,C. Rojas,A. Tortajada,M. Espin,G. Segura,D. 2014. Una mutante de Azotobacter vinelandii productora de PHB que carece de los en: Mendez,B. Bioplasticos. Lisboa, Portugal. Editorial CYTED. pags. 23-31

Segura,D. Noguez,R. Espin,G. 2008. Contaminación ambiental y bacterias productoras de plásticos biodegradables en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 31. Mexico, D.F.. UNAM. pags. 361-372

Espin,G. 2001. Genetic control of cyst formation in Azotobacter vinelandii en: Nitrogen Fixation Research Center XX Anniversary. pags. 122-125

Espin,G. 2001. Biologia de Azotobacter vinelandii en: Martinez-Romero,E. Microbios en linea. Coordinacion de la Investigacion Cientifica. pags. 91-108

Mora,J. Davila,G. Espin,G. Gonzalez,A. Guzman,J. Hernandez.G. Hummelt,G. Lara,M. Martinez,E. Mora,Y. Romero,D. 1980. Glutamine Metabolism in Neurospora crassa en: Palacios,J. Glutamine: Metabolism, Enzymology, and Regulation. Academic Press. pags. 185-211 *

Otras Publicaciones

Espin,G. Moreno,S. Segura,D. Moreno,Y. 2006. Alkylresorcinols synthesis and its role in the production of cysts in Azotobacter Revista Latinoamericana de Microbiologia, 48, 129-130.

* Indica publicación con otra institución de adscripción