IBT-UNAM : Dr. Ernesto Ortiz Suri
- Licenciatura: Biología, Universidad Estatal de Moscu M.V. Lomonosov, Fac. de Biología, Rusia (1988-1992) - Maestría: en Bioquímica, Universidad estatal de Moscu M.V. Lononosov, Fac. de Biología, Rusia (1992-1993) - Doctorado: en Biotecnología, IBt-UNAM (1998) - Medalla de Bronce en la XIX Olimpiada Mundial de Química. Academia de Ciencias de Hungría/Comite de la IchO (1986) - Mencion honorífica en la XX Olimpiada Mundial de Química. Comite de la IchO. Finlandia, (1987) - Medalla "Yu.A. Obchinnikov" al mejor graduado del ano. Catedra de Química Bioorganica, Fac. de Biología, Universidad Estatal de Moscu "M.V. Lomonosov", Rusia (1993) - Diploma Rojo, maxima distincion de la Maestría en Rusia. Título recibido con honores. Universidad Estatal de Moscu "M.V. Lomonosov", Rusia (1993) - Estancia de investigacion en el CIFN-UNAM (1998-2000)
Estudiantes Ing. Gustavo Delgado
Publicaciones recientes
Santana,F.L. Estrada,K. Ortiz,E. Corzo,G.
2021. Reptilian b-defensins: expanding the repertoire of known crocodylian peptides Peptides, 136, 170473.
Cid-Uribe,J.I. Veytia-Bucheli,J.I. Romero-Gutierrez,T. Ortiz,E. Possani,L.D.
2020. Scorpion venomics: a 2019 overview Expert Review of Proteomics, 17, 67-83.
Santibanez-Lopez,C.E. Graham,M.R. Sharma,P.P. Ortiz,E. Possani,L.D.
2019. Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures Toxins (Basel), 11, E637.
Delgado-Prudencio,G. Possani,L.D. Becerril,B. Ortiz,E.
2019. The Dual alpha-Amidation System in Scorpion Venom Glands Toxins (Basel), 11, 425.
Cid-Uribe,J.I. Meneses,E.P. Batista,C.V.F. Ortiz,E. Possani,L.D.
2019. Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879) Toxins (Basel), 11, 247.
Okada,M. Ortiz,E. Corzo,G. Possani,L.D.
2019. Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach PLoS ONE, 14, e0215391.
Bernaldez-Sarabia,J. Figueroa-Montiel,A. Duenas,S. Cervantes-Luevano,K. Beltran,J.A. Ortiz,E. Jimenez,S. Possani,L.D. Paniagua-Solis,J.F. Gonzalez-Canudas,J. Licea-Navarro,A.
2019. The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity Toxins (Basel), 11, E128.
Carcamo-Noriega,E.N. Possani,L.D. Ortiz,E.
2019. Venom content and toxicity regeneration after venom gland depletion by electrostimulation in the scorpion Centruroides limpidus Toxicon, 157, 87-92.
Romero-Gutierrez,M.T. Santibanez-Lopez,C.E. Jimenez-Vargas,J.M. Batista,C.V.F. Ortiz,E. Possani,L.D.
2018. Transcriptomic and Proteomic Analyses Reveal the Diversity of Venom Components from the Vaejovid Scorpion Serradigitus gertschi Toxins (Basel), 10, 359.
Cid-Uribe,J.I. Santibanez-Lopez,C.E. Meneses,E.P. Batista,C.V.F. Jimenez-Vargas,J.M. Ortiz,E. Possani,L.D.
2018. The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses Toxicon, 151, 47-62.
Ortiz,E. Possani,L.D.
2018. Scorpion toxins to unravel the conundrum of ion channel structure and functioning Toxicon, 150, 17-27.
Romero-Gutierrez,T. Peguero-Sanchez,E. Cevallos,M.A. Batista,C.V.F. Ortiz,E. Possani,L.D.
2017. A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Techonologies Toxins (Basel), 9, 399.
Garcia-Garcia,F. Corrales-Garcia,L.L. Olamendi-Portugal,T. Restano-Cassulini,R. Vega,R. Vega,M. Ortiz,E. Sandoval-Lopez,G. Soto,E. Corzo,G.
2017. Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius Process Biochemistry, 62, 205-214.
Santibanez-Lopez,C.E. Cid-Uribe,J.I. Zamudio,F.Z. Batista,C.V.F. Ortiz,E. Possani,L.D.
2017. Venom gland transcriptomic and venom proteomic analyses of the scorpion Megacormus gertschi Diaz-Najera, 1966 (Scorpiones: Euscorpiidae: Megacorminae) Toxicon, 133, 95-109.
Hernandez-Vargas,M.J. Gil,J. Lozano,L. Pedraza-Escalona,M. Ortiz,E. Encarnacion-Guevara,S. Alagon,A. Corzo,G.
2017. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis Journal of Proteomics, 162, 30-39.
Sanchez-Reyez,A. Batista-Garcia,R.A. Valdes-Garcia,G. Ortiz,E. Perezgasga,L. Zarate-Romero,A. Pastor,N. Folch-Mallol,J.L.
2017. A Family 13 thioesterase isolated from an activated sludge metagenome: Insights into aromatic compounds metabolism Proteins, 85, 1222-1237.
Jimenez-Vargas,J.M. Quintero-Hernandez,V. Gonzalez-Morales,L. Ortiz,E. Possani,L.D.
2017. Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms Toxicon, 128, 5-14 [Corrigendum 130 (2017) 126].
Santibanez-Lopez,C.E. Cid-Uribe,J.I. Batista,C.V. Ortiz,E. Possani,L.D.
2016. Venom Gland Transcriptomic and Proteomic Analyses of the Enigmatic Scorpion Superstitionia donensis (Scorpiones: Superstitioniidae), with Insights on the Evolution of Its Venom Components Toxins (Basel), 8, .
Estrada,G. Silva,A.O. Villegas,E. Ortiz,E. Beirao,P.S.L. Corzo,G.
2016. Heterologous expression of five disulfide-bonded insecticidal spider peptides Toxicon, 119, 152-158.
Figueroa-Montiel,A. Ramos,M.A. Mares,R.E. Duenas,S. Pimienta,G. Ortiz,E. Possani,L.D. Licea-Navarro,A.F.
2016. In Silico Identification of Protein Disulfide Isomerase Gene Families in the De Novo Assembled Transcriptomes of Four Different Species of the Genus Conus PLoS ONE, 11, e0148390.
Ramirez-Carreto,S. Jimenez-Vargas,J.M. Rivas-Santiago,B. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2015. Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity Peptides, 73, 51-59.
Ortiz,E. Possani,L.D.
2015. The unfulfilled promises of scorpion insectotoxins Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, .
Zuniga-Navarrete,F. Gomez,I. Pena,G. Amaro,I. Ortiz,E. Becerril,B. Ibarra,J.E. Bravo,A. Soberon,M.
2015. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12 Insect Biochemistry and Molecular Biology, 59, 50-57.
Quintero-Hernandez,V. Ramirez-Carreto,S. Romero-Gutierrez,M.T. Valdez-Velazquez,L.L. Becerril,B. Possani,L.D. Ortiz,E.
2015. Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus PLoS ONE, 10, e0117188.
Ortiz,E. Gurrola,G.B. Schwartz,E.F. Possani,L.D.
2015. Scorpion venom components as potential candidates for drug development Toxicon, 93, 125-135.
Campos-Oliver,A. Quiroz-Castaneda,R.E. Ortiz,E. Folch-Mallol,J.L.
2014. Cloning and expression of a hypothetical loosenin from Neurospora crassa Revista Latinoamericana de Biotecnologia Ambiental y Algal, 4, 1-7.
Ortiz,E. Rendon-Anaya,M. Rego,S.C. Schwartz,E.F. Possani,L.D.
2014. Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera Biochimica et Biophysica Acta (BBA), 1840, 1738-1746.
Gonzalez-Andrade,M. Becerril-Lujan,B. Sanchez-Lopez,R. Cecena-Alvarez,H. Perez-Carreon,J.I. Ortiz-Suri,E. Fernandez-Velasco,D.A. Del Pozo-Yauner,L.
2013. Mutational and genetic determinants of lambda6 light chain amyloidogenesis Febs Journal, 280, 6173-6183.
Corrales-Garcia,L. Ortiz,E. Castaneda-Delgado,J. Rivas-Santiago,B. Corzo,G.
2013. Bacterial expression and antibiotic activities of recombinant variants of human beta-defensins on pathogenic bacteria and M. tuberculosis Protein Expression and Purification, 89, 33-43.
Aguilar,M.B. Ortiz,E. Kaas,Q. Lopez-Vera,E. Becerril,B. Possani,L.D. de la Cotera,E.P.
2013. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily Peptides, 41, 17-20.
Ramirez-Carreto,S. Quintero-Hernandez,V. Jimenez-Vargas,J.M. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2012. Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae Peptides, 34, 290-295.
Quintero-Hernandez,V. Ortiz,E. Rendon,M.R. Schwartz,E.F. Becerril,B. Corzo,G. Possani,L.D.
2011. Scorpion and spider venom peptides: Gene cloning and peptide expression Toxicon, 58, 644-663.
Estrada,G. Restano-Cassulini,R. Ortiz,E. Possani,L.D. Corzo,G.
2011. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6 Peptides, 32, 75-79 (Correction vol 32 p.1096).
Hernandez-Santoyo,A. Del Pozo-Yauner,L. Fuentes-Silva,D. Ortiz,E. Rudino-Pinera,E. Sanchez-Lopez,R. Horjales,E. Becerril,B. Rodriguez-Romero,A.
2010. A single mutation at the sheet switch region results in conformational changes favoring lambda6-light-chain fibrillogenesis Journal of Molecular Biology, 396, 280-292.
Del Pozo-Yauner,L. Ortiz,E. Sanchez,R. Sanchez-Lopez,R. Guereca,L. Murphy,C.L. Allen,A. Wall,J.S. Fernandez-Velasco,D.A. Solomon,A. Becerril,B.
2008. Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains Proteins, 72, 684-692.
Lopez-Vera,E. Aguilar,M.B. Schiavon,E. Marinzi,C. Ortiz,E. Restano-Cassulini,R. Batista,C.V.F. Possani,L.D. Heimer de la Cotera,E.P. Peri,F. Becerril,B. Wanke,E.
2007. Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors Febs Journal, 274, 3972-3985.
Estrada,G. Garcia,B.I. Schiavon,E. Ortiz,E. Cestele,S. Wanke,E. Possani,L.D. Corzo,G.
2007. Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro Biochimica et Biophysica Acta (BBA), 1770, 1161-1168.
Del Pozo-Yauner,L. Ortiz,E. Becerril,B.
2006. The CDR1 of the human lambdaVI light chains adopts a new canonical structure Proteins, 62, 122-129.
Aguilar,M.B. Lopez-Vera,E. Ortiz,E. Becerril,B. Possani,L.D. Olivera,B.M. Heimer de la Cotera,E.P.
2005. A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues Biochemistry, 44, 11130-11136.
Juarez-Gonzalez,V.R. Riano-Umbarila,L. Quintero-Hernandez,V. Olamendi-Portugal,T. Ortiz-Leon,M. Ortiz,E. Possani,L.D. Becerril,B.
2005. Directed Evolution, Phage Display and Combination of Evolved Mutants: A Strategy to Recover the Neutralization Properties of the scFv Version of BCF2 a Neutralizing Monoclonal Antibody Specific to Scorpion Toxin Cn2 Journal of Molecular Biology, 346, 1287-1297.
Manoutcharian,K. Acero,G. Munguia,M.E. Becerril,B. Massieu,L. Govezensky,T. Ortiz,E. Marks,J.D. Cao,C. Ugen,K. Gevorkian,G.
2004. Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1-42 Neurobiology of Disease, 17, 114-121.
Romero,D. Martinez-Salazar,J. Ortiz,E. Rodriguez,C. Valencia-Morales,E.
1999. Repeated sequences in bacterial chromosomes and plasmids: a glimpse from sequenced genomes Research in Microbiology, 150, 735-743 * .
Ortiz,E. Estrada,G. Lizardi,P.M.
1998. PNA molecular beacons for rapid detection of PCR amplicons Mol.Cell Probes, 12, 219-226.
Larin,D.I. Shakhparonov,M.I. Ortiz,E. Kostina,M.B. Modyanov,N.N.
1994. Expression and Purification of Fusion Proteins Containing Na+, K+-Atpase Alpha-Subunit Fragments That Are Located Near the Membrane.Biologicheskie Membrany, 11, 469-475 * .
Larin,D.I. Shakhparonov,M.I. Ortiz,E. Kostina,M.B. Modyanov,N.N.
1994. INTRACELLULAR LOCATION OF THE EPITOPES OF 2 NEW MONOCLONAL- ANTIBODIES AGAINST THE VAL(928)-LYS(945) FRAGMENT OF THE ALPHA- SUBUNIT OF NA+,K+-ATPASE.Biologicheskie Membrany, 11, 605-613 * .
Garcia,F. Villegas,E. Ortiz,E. Corzo,G. 2015. Structural Diversity and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from Spiders en: de Lima,M.E. Spider Venoms. Springer Netherlands. pags. 1-20
Chavez-Haro,A.L. Ortiz,E. 2014. Scorpionism and Dangerous Species of Mexico en: Rodriguez-de-la-Vega,R. Scorpion Venoms. Springer Netherlands. pags. 201-213
Rendon-Anaya,M. Camargos,T.S. Ortiz,E. 2014. Scorpion Venom Gland Transcriptomics en: Gopalakrishnakone,P. Scorpion Venoms. Springer Netherlands. pags. 531-545
del Pozo-Yauner,L. Ortiz,E. Becerril,B. 2009. Diseases related to protein misfolding en: Fernandez-Velasco,D.A. Advances in Protein Physical Chemistry. Kerala. Research Signpost. pags. 469-501
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Patentes
Possani, L.D., Quintero, V., Gonzalez, L., Jiménez-Vargas, J.M., Ortiz, E., Corzo, G., Becerril, B., 2016 Composición farmacéutica de proteínas híbridas recombinantes capaces de generar anticuerpos neutralizantes en contra del veneno de alacranes.UNAM México. (en trámite)
Ortiz, E., Ramírez-Carreto, S., Jiménez-Vargas, J.M., Corzo, G., Possani, L.D., 2015 Péptidos del alacrán Vaejovispunctatus como antibióticos contra Mycobacterium tuberculosis y otras bacterias y levaduras patógenas. Oficina de Patentes Mexico. (en trámite)
* Indica publicación con otra institución de adscripción