IBT-UNAM : Dr. David Valle García
Dr. David Valle García
Grupo del Dr. Martin Gustavo Pedraza
email: david.valle@mail.ibt.unam.mx
Teléfonos
Laboratorio +52 (777) 329-1777 ext 38259. red UNAM 38259
- Licenciatura: Ciencias Genómicas, Centro de Ciencias Genómicas/Instituto de Biotecnología, UNAM (2004-2008)
Publicaciones recientes
Zhang,Y. Xie,X. Yeganeh,P.N. Lee,D.J. Valle-Garcia,D. Meza-Sosa,K.F. Junqueira,C. Su,J. Luo,H.R. Hide,W. Lieberman,J.
2021. Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown Proceedings of the National Academy of Sciences of the United States of America, 118, e2022830118.
Sendinc,E. Valle-Garcia,D. Jiao,A. Shi,Y.
2020. Analysis of m6A RNA methylation in Caenorhabditis elegans Cell Discovery, 6, 47 * .
Byrum,A.K. Carvajal-Maldonado,D. Mudge,M.C. Valle-Garcia,D. Majid,M.C. Patel,R. Sowa,M.E. Gygi,S.P. Harper,J.W. Shi,Y. Vindigni,A. Mosammaparast,N.
2019. Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function Journal of Cell Biology, 218, 422-432 * .
Sendinc,E. Valle-Garcia,D. Dhall,A. Chen,H. Henriques,T. Navarrete-Perea,J. Sheng,W. Gygi,S.P. Adelman,K. Shi,Y.
2019. PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression Molecular Cell, 75, 620-630 * .
Qadeer,Z.A. Valle-Garcia,D. Hasson,D. Sun,Z. Cook,A. Nguyen,C. Soriano,A. Ma,A. Griffiths,L.M. Zeineldin,M. Filipescu,D. Jubierre,L. Chowdhury,A. Deevy,O. Chen,X. Finkelstein,D.B. Bahrami,A. Stewart,E. Federico,S. Gallego,S. Dekio,F. Fowkes,M. Meni,D. Maris,J.M. Weiss,W.A. Roberts,S.S. Cheung,N.V. Jin,J. Segura,M.F. Dyer,M.A. Bernstein,E.
2019. ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures Cancer Cell, 36, 512-527 * .
Dyer,M.A. Qadeer,Z.A. Valle-Garcia,D. Bernstein,E.
2017. ATRX and DAXX: Mechanisms and Mutations Cold Spring Harbor Perspectives in Medicine, 7, * .
Fontanals-Cirera,B. Hasson,D. Vardabasso,C. Di,M.R. Agrawal,P. Chowdhury,A. Gantz,M. de Pablos-Aragoneses,A. Morgenstern,A. Wu,P. Filipescu,D. Valle-Garcia,D. Darvishian,F. Roe,J.S. Davies,M.A. Vakoc,C.R. Hernando,E. Bernstein,E.
2017. Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene Molecular Cell, 68, 731-744 * .
Valle-Garcia,D. Qadeer,Z.A. McHugh,D.S. Ghiraldini,F.G. Chowdhury,A.H. Hasson,D. Dyer,M.A. Recillas-Targa,F. Bernstein,E.
2016. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment Epigenetics, 11, 398-414 * .
Vardabasso,C. Gaspar-Maia,A. Hasson,D. Punzeler,S. Valle-Garcia,D. Straub,T. Keilhauer,E.C. Strub,T. Dong,J. Panda,T. Chung,C.Y. Yao,J.L. Singh,R. Segura,M.F. Fontanals-Cirera,B. Verma,A. Mann,M. Hernando,E. Hake,S.B. Bernstein,E.
2015. Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma Molecular Cell, 59, 75-88 * .
Qadeer,Z.A. Harcharik,S. Valle-Garcia,D. Chen,C. Birge,M.B. Vardabasso,C. Duarte,L.F. Bernstein,E.
2014. Decreased expression of the chromatin remodeler ATRX associates with melanoma progression Journal of Investigative Dermatology, 134, 1768-1772 * .
Valle-Garcia,D. Griffiths,L.M. Dyer,M.A. Bernstein,E. Recillas-Targa,F.
2014. The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure Springerplus, 3, 222 * .
Gaspar-Maia,A. Qadeer,Z.A. Hasson,D. Ratnakumar,K. Leu,N.A. Leroy,G. Liu,S. Costanzi,C. Valle-Garcia,D. Schaniel,C. Lemischka,I. Garcia,B. Pehrson,J.R. Bernstein,E.
2013. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency Nature Communications, 4, 1565 * .
Meza-Sosa,K.F. Valle-Garcia,D. Pedraza-Alva,G. Perez-Martinez,L.
2012. Role of microRNAs in central nervous system development and pathology Journal of Neuroscience Research, 90, 1-12.
Arzate-Mejia,R.G. Valle-Garcia,D. Recillas-Targa,F.
2011. Signaling epigenetics: novel insights on cell signaling and epigenetic regulation IUBMB Life, 63, 881-895 * .
Zepeda-Mendoza,C.J. Lemus,T. Yanez,O. Garcia,D. Valle-Garcia,D. Meza-Sosa,K.F. Gutierrez-Arcelus,M. Marquez-Ortiz,Y. Dominguez-Vidana,R. Gonzaga-Jauregui,C. Flores,M. Palacios,R.
2010. Identical repeated backbone of the human genome BMC Genomics, 11, 60.
Otras Publicaciones Meza-Sosa,K.F. Valle-Garcia,D. Pedraza-Alva,G. Perez-Martinez,L.
2013. MicroARNs, los pequeños grandes actores del sistema nervioso Ciencia, Revista de la Academia Mexicana de Ciencia, 64, 79-86.
* Indica publicación con otra institución de adscripción
Investigador en estancia postdoctoral