IBT-UNAM : Dr. Gerardo Corzo Burguete
- Licenciatura: Ingeniero en Bioquimica Industrial,Universidad Autonoma Metropolitana-Iztapalapa, (1986)
Estudiantes Dra. Maria Jose Hernández "Análisis proteómico y transcriptómico de la saliva de Triatoma pallidipennis y la búsqueda de proteínas con potencial terapéutico"
C.D. Marcela Leticia Galeana
T.L. Andrid López
Lic. Marcos Hugo Salazar
M.C. Germán Obed Aguilar
Biol. Victor Carpanta
M.C. Pavel Andrei Montero
Erika Corzo
Ing. Astrid Tuxpan
Biol. David Antonio Villaseñor
Lic. Felix Leonardo Santana
M.C. Jesus Angel Borrego "Consecuencias de mutaciones en residuos aminoacídicos de la neurotoxina Magi4 en su actividad biológica y especificidad hacia insectos y mamíferos"
Maricela Guerrero
Galilea Jaimes
M.C. Marco Antonio Ibarra
Biol. Miguel Angel Mejia
Lic. Diana Alvarado
Publicaciones recientes
Archundia,I.G. de la Rosa,G. Olvera,F. Calderon,A. Benard-Valle,M. Alagon,A. Corzo,G.
2021. Assessment of neutralization of Micrurus venoms with a blend of anti-Micrurus tener and anti-ScNtx antibodies Vaccine, 39, 1000-1006.
Santana,F.L. Estrada,K. Ortiz,E. Corzo,G.
2021. Reptilian b-defensins: expanding the repertoire of known crocodylian peptides Peptides, 136, 170473.
Alvarado,D. Cardoso-Arenas,S. Corrales-Garcia,L.L. Clement,H. Arenas,I. Montero-Dominguez,P.A. Olamendi-Portugal,T. Zamudio,F. Agota,C. Borrego,J. Panyi,G. Papp,F. Corzo,G.
2021. A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5 Frontiers in Pharmacology, 11, 563858.
Pelaez-Coyotl,E.A. Barrios,P.J. Mucino,G. Moreno-Blas,D. Costas,M. Montiel,M.T. Diener,C. Uribe-Carvajal,S. Massieu,L. Castro-Obregon,S. Espinosa,O.R. Barrios-Payan,J. Leon-Contreras,J.C. Corzo,G. Hernandez-Pando,R. Del Rio,G.
2020. Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis Pharmaceutics, 12, .
Arenas,I. Ibarra,M.A. Santana,F.L. Villegas,E. Hancock,R.E.W. Corzo,G.
2020. In vitro and in vivo antibiotic capacity of two host defence peptides Antimicrobial Agents and Chemotherapy, 64, e00145-20.
Lino-Lopez,G.J. Valdez-Velazquez,L.L. Corzo,G. Romero-Gutierrez,T. Jimenez-Vargas,J.M. Rodriguez-Vazquez,A. Vazquez-Vuelvas,O.F. Gonzalez-Carrillo,G.
2020. Venom gland transcriptome from Heloderma horridum horridum by high-throughput sequencing Toxicon, 180, 62-78.
Borrego,J. Clement,H. Corrales-Garcia,L.L. Arenas,I. Corzo,G.
2020. Key amino acid residues involved in mammalian and insecticidal activities of Magi4 and Hv1b, cysteine-rich spider peptides from the delta-atracotoxin family Amino Acids, 52, 465-475.
Corrales-Garcia,L.L. Serrano-Carreon,L. Corzo,G.
2020. Improving the heterologous expression of human beta-defensin 2 (HBD2) using an experimental design Protein Expression and Purification, 167, 105539.
Bertrand,B. Munusamy,S. Espinosa-Romero,J.F. Corzo,G. Arenas-Sosa,I. Galvan-Hernandez,A. Ortega-Blake,I. Hernandez-Adame,P.L. Ruiz-Garcia,J. Velasco-Bolom,J.L. Garduno-Juarez,R. Munoz-Garay,C.
2020. Biophysical characterization of the insertion of two potent antimicrobial peptides-Pin2 and its variant Pin2[GVG] in biological model membranes Biochimica et Biophysica Acta (BBA), 1862, 183105.
Velasco-Bolom,J.L. Corzo,G. Garduno-Juarez,R.
2020. Folding profiles of antimicrobial scorpion venom-derived peptides on hydrophobic surfaces: a molecular dynamics study Journal of Biomolecular Structure and Dynamics, 38, 2928-2938.
Rodriguez,A. Pedersen,M.O. Villegas,E. Rivas-Santiago,B. Villegas-Moreno,J. Amero,C. Norton,R.S. Corzo,G.
2020. Antimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10 Proteins: Structure, Function and Bioinformatics, 88, 175-186.
Clement,H. Corrales-Garcia,L.L. Bolanos,D. Corzo,G. Villegas,E.
2019. Immunogenic Properties of Recombinant Enzymes from Bothrops Ammodytoides Towards the Generation of Neutralizing Antibodies against Its Own Venom Toxins (Basel), 11, 702.
de la Rosa,G. Olvera,F. Archundia,I.G. Lomonte,B. Alagon,A. Corzo,G.
2019. Horse immunization with short-chain consensus a-neurotoxin generates antibodies against broad spectrum of elapid venomous species Nature Communications, 10, 3642.
Navarro-Gonzalez,S.S. Ramirez-Trujillo,J.A. Pena-Chora,G. Gaytan,P. Roldan-Salgado,A. Corzo,G. Lina-Garcia,L.P. Hernandez-Velazquez,V.M. Suarez-Rodriguez,R.
2019. Enhanced Tolerance against a Fungal Pathogen and Insect Resistance in Transgenic Tobacco Plants Overexpressing an Endochitinase Gene from Serratia marcescens International Journal of Molecular Sciences, 20, 3482.
Bondarenko,O. Corzo,G. Santana,F.L. del Rio-Portilla,F. Darszon,A. Lopez-Gonzalez,I.
2019. Non-enzymatically oxidized arachidonic acid regulates T-type Ca(2+) currents in mouse spermatogenic cells FEBS Letters, 593, 1735-1750 [Preprint anteriormente en biorXiv].
Okada,M. Ortiz,E. Corzo,G. Possani,L.D.
2019. Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach PLoS ONE, 14, e0215391.
Clement,H. Corzo,G. Neri-Castro,E. Arenas,I. Hajos,S. de Roodt,A.R. Villegas,E.
2019. cDNA cloning, heterologous expression, protein folding and immunogenic properties of a phospholipase A2 from Bothrops ammodytoides venom Protein Expression and Purification, 154, 33-43.
de la Rosa,G. Olvera,F. Cruz,E. Paniagua,D. Corzo,G.
2018. Use of irradiated elapid and viperid venoms for antivenom production in small and large animals Toxicon, 155, 32-37.
Luna-Bulbarela,A. Tinoco-Valencia,R. Corzo,G. Kazuma,K. Konno,K. Galindo,E. Serrano-Carreon,L.
2018. Effects of bacillomycin D homologues produced by Bacillus amyloliquefaciens 83 on growth and viability of Colletotrichum gloeosporioides at different physiological stages Biological Control, 127, 145-154.
de la Rosa,G. Corrales-Garcia,L.L. Rodriguez-Ruiz,X. Lopez-Vera,E. Corzo,G.
2018. Short-chain consensus alpha-neurotoxin: a synthetic 60-mer peptide with generic traits and enhanced immunogenic properties Amino Acids, 50, 885-895.
Walker,A.A. Hernandez-Vargas,M.J. Corzo,G. Fry,B.G. King,G.F.
2018. Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera Cellular and Molecular Life Sciences, 75, 3215-3229.
Guerrero-Garzon,J.F. Benard-Valle,M. Restano-Cassulini,R. Zamudio,F. Corzo,G. Alagon,A. Olvera-Rodriguez,A.
2018. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema Biochimie, 147, 114-121.
Titaux-Delgado,G. Carrillo,E. Mendoza,A. Mayorga-Flores,M. Escobedo-Gonzalez,F.C. Cano-Sanchez,P. Lopez-Vera,E. Corzo,G. del Rio-Portilla,F.
2018. Successful refolding and NMR structure of rMagi3: A disulfide-rich insecticidal spider toxin Protein Science, 27, 692-701.
Salazar,M.H. Arenas,I. Corrales-Garcia,L.L. Miranda,R. Velez,S. Sanchez,J. Mendoza,K. Cleghorn,J. Zamudio,F.Z. Castillo,A. Possani,L.D. Corzo,G. Acosta,H.
2018. Venoms of Centruroides and Tityus species from Panama and their main toxic fractions Toxicon, 141, 79-87.
Velasco-Bolom,J.L. Corzo,G. Garduno-Juarez,R.
2018. Molecular Dynamics Simulation Of The Membrane Binding And Disruption Mechanisms By Antimicrobial Scorpion Venom-Derived Peptides Journal of Biomolecular Structure and Dynamics, 36, 2070-2084.
Garcia-Garcia,F. Corrales-Garcia,L.L. Olamendi-Portugal,T. Restano-Cassulini,R. Vega,R. Vega,M. Ortiz,E. Sandoval-Lopez,G. Soto,E. Corzo,G.
2017. Identification, chemical synthesis and heterologous expression of an antinociceptive peptide from the veined tree frog Trachycephalus typhonius Process Biochemistry, 62, 205-214.
Guillen-Chable,F. Arenas-Sosa,I. Islas-Flores,I. Corzo,G. Martinez-Liu,C. Estrada,G.
2017. Antibacterial activity and phospholipid recognition of the recombinant defensin J1-1 from Capsicum genus Protein Expression and Purification, 136, 45-51.
Hernandez-Vargas,M.J. Gil,J. Lozano,L. Pedraza-Escalona,M. Ortiz,E. Encarnacion-Guevara,S. Alagon,A. Corzo,G.
2017. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis Journal of Proteomics, 162, 30-39.
Corzo,G. Espino-Solis,G.P.
2017. Selected scorpion toxin exposures induce cytokine release in human peripheral blood mononuclear cells Toxicon, 127, 56-62.
de la Rosa,G. Pastor,N. Alagon,A. Corzo,G.
2017. Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms Peptides, 88, 80-86.
Montero-Alejo,V. Corzo,G. Porro-Suardiaz,J. Pardo-Ruiz,Z. Perera,E. Rodriguez-Viera,L. Sanchez-Diaz,G. Hernandez-Rodriguez,E.W. Alvarez,C. Peigneur,S. Tytgat,J. Perdomo-Morales,R.
2017. Panusin represents a new family of beta-defensin-like peptides in invertebrates Developmental & Comparative Immunology, 67, 310-321.
Carrillo-Sancen,G. Carrasco-Navarro,U. Tomasini-Campocosio,A. Corzo,G. Pedraza-Escalona,M. Favela-Torres,E.
2016. Effect of glucose as a carbon repressor on the extracellular proteome of Aspergillus niger during the production of amylases by solid state cultivation Process Biochemistry, 51, 2001-2010.
Clement,H. Flores,V. de la Rosa,G. Zamudio,F. Alagon,A. Corzo,G.
2016. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis Journal of Venomous Animals and Toxins Including Tropical Diseases, 22, 25.
Estrada,G. Silva,A.O. Villegas,E. Ortiz,E. Beirao,P.S.L. Corzo,G.
2016. Heterologous expression of five disulfide-bonded insecticidal spider peptides Toxicon, 119, 152-158.
Diener,C. Garza Ramos Martinez G. Moreno Blas D. Castillo Gonzalez,D.A. Corzo,G. Castro-Obregon,S. Del Rio,G.
2016. Effective Design of Multifunctional Peptides by Combining Compatible Functions PLoS Computational Biology, 12, e1004786.
Arenas,I. Villegas,E. Walls,O. Barrios,H. Rodriguez,R. Corzo,G.
2016. Antimicrobial Activity and Stability of Short and Long Based Arachnid Synthetic Peptides in the Presence of Commercial Antibiotics Molecules, 21, 225.
Hernandez-Vargas,M.J. Santibanez-Lopez,C.E. Corzo,G.
2016. An Insight into the Triabin Protein Family of American Hematophagous Reduviids: Functional, Structural and Phylogenetic Analysis Toxins (Basel), 8, .
Ramirez-Carreto,S. Jimenez-Vargas,J.M. Rivas-Santiago,B. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2015. Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity Peptides, 73, 51-59.
Clement,H. Flores,V. Diego-Garcia,E. Corrales-Garcia,L. Villegas,E. Corzo,G.
2015. A comparison between the recombinant expression and chemical synthesis of a short cysteine-rich insecticidal spider peptide Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, 19.
Okada,M. Corzo,G. Romero-Perez,G.A. Coronas,F. Matsuda,H. Possani,L.D.
2015. A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain Biochimica et Biophysica Acta (BBA), 1850, 657-666.
Rodriguez,A. Villegas,E. Montoya-Rosales,A. Rivas-Santiago,B. Corzo,G.
2014. Characterization of Antibacterial and Hemolytic Activity of Synthetic Pandinin 2 Variants and Their Inhibition against Mycobacterium tuberculosis PLoS ONE, 9, e101742.
Nomura,K. Villegas,E. Corzo,G.
2014. Solid-state NMR studies of antimicrobial peptides from arachnid venoms Biomedical Spectroscopy and Imaging, 3, 107-120.
Picco,C. Corzo,G. Possani,L.D. Prestipino,G.
2014. Interaction of the scorpion toxin Discrepin with Kv4.3 channels and A-type K channels in cerebellum granular cells Biochimica et Biophysica Acta, 1840, 2744-2751.
Bandala,Y. Reyes-Rangel,G. Obregon-Zuniga,A. Cruz-Hernandez,C. Corzo,G. Juaristi,E.
2014. trans-Hexahydrobenzoxazolidinones in the Enantioselective Synthesis of b2-Amino Acids Containing Proteinogenic Side Chains European Journal of Organic Chemistry, 2014, 2275-2283.
Ardisson-Araujo,D.M. de Silva-Morgado,F. Schwartz,E.F. Corzo,G. Ribeiro,B.M.
2013. A New theraphosid Spider Toxin Causes Early Insect Cell Death by Necrosis When Expressed In Vitro during Recombinant Baculovirus Infection PLoS ONE, 8, e84404.
Perdomo-Morales,R. Montero-Alejo,V. Corzo,G. Besada,V. Vega-Hurtado,Y. Gonzalez-Gonzalez,Y. Perera,E. Porto-Verdecia,M.
2013. The trypsin inhibitor panulirin regulates the prophenoloxidase activating system in the spiny lobster Panulirus argus Journal of Biological Chemistry, 288, 31867-31879.
Carmona,G. Rodriguez,A. Juarez,D. Corzo,G. Villegas,E.
2013. Improved Protease Stability of the Antimicrobial Peptide Pin2 Substituted with D-Amino Acids Protein Journal, 32, 456-466.
Bernaldez,J. Roman-Gonzalez,S.A. Martinez,O. Jimenez,S. Vivas,O. Arenas,I. Corzo,G. Arreguin,R. Garcia,D.E. Possani,L.D. Licea,A.
2013. A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity Marine Drugs, 11, 1188-1202.
Corrales-Garcia,L. Ortiz,E. Castaneda-Delgado,J. Rivas-Santiago,B. Corzo,G.
2013. Bacterial expression and antibiotic activities of recombinant variants of human beta-defensins on pathogenic bacteria and M. tuberculosis Protein Expression and Purification, 89, 33-43.
Caliskan,F. Quintero-Hernandez,V. Restano-Cassulini,R. Coronas-Valderrama,F.I. Corzo,G. Possani,L.D.
2013. Molecular cloning and biochemical characterization of the first Na+-channel alpha-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom Biochimie, 95, 1216-1222.
Garcia,F. Villegas,E. Espino-Solis,G.P. Rodriguez,A. Paniagua-Solis,J.F. Sandoval-Lopez,G. Possani,L.D. Corzo,G.
2013. Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics Journal of Antibiotics, 66, 3-10.
Caliskan,F. Garcia,B.I. Coronas,F.I. Restano-Cassulini,R. Korkmaz,F. Sahin,Y. Corzo,G. Possani,L.D.
2012. Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda Peptides, 37, 106-112.
Ramirez-Carreto,S. Quintero-Hernandez,V. Jimenez-Vargas,J.M. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2012. Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae Peptides, 34, 290-295.
Saucedo,A.L. Del Rio,F. Picco,C. Estrada,G. Prestipino,G. Possani,L.D. Delepierre,M. Corzo,G.
2012. Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion suffusus, and their effects on Nav1.5 Sodium channels Biochimica et Biophysica Acta (BBA), 1824, 478-487.
Schiavon,E. Pedraza-Escalona,M. Gurrola,G.B. Olamendi-Portugal,T. Corzo,G. Wanke,E. Possani,L.D.
2012. Negative-shift activation, current reduction and resurgent currents induced by beta-toxins from Centruroides scorpions in sodium channels Toxicon, 59, 283-293.
Quintero-Hernandez,V. Ortiz,E. Rendon,M.R. Schwartz,E.F. Becerril,B. Corzo,G. Possani,L.D.
2011. Scorpion and spider venom peptides: Gene cloning and peptide expression Toxicon, 58, 644-663.
Espino-Solis,G.P. Estrada,G. Olamendi-Portugal,T. Villegas,E. Zamudio,F. Cestele,S. Possani,L.D. Corzo,G.
2011. Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus Toxicon, 57, 739-746.
Riano-Umbarila,L. Contreras-Ferrat,G. Olamendi-Portugal,T. Morelos-Juarez,C. Corzo,G. Possani,L.D. Becerril,B.
2011. Exploiting cross-reactivity to neutralize two different scorpion venoms with one single-chain antibody fragment Journal of Biological Chemistry, 286, 6143-6151.
Estrada,G. Restano-Cassulini,R. Ortiz,E. Possani,L.D. Corzo,G.
2011. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6 Peptides, 32, 75-79 (Correction vol 32 p.1096).
Corrales-Garcia,L.L. Possani,L.D. Corzo,G.
2011. Expression systems of human beta-defensins: vectors, purification and biological activities Amino Acids, 40, 5-13.
Rodriguez,A. Villegas,E. Satake,H. Possani,L.D. Corzo,G.
2011. Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index Amino Acids, 40, 61-68.
Yamaji,N. Little,M.J. Nishio,H. Billen,B. Villegas,E. Nishiuchi,Y. Tytgat,J. Nicholson,G.M. Corzo,G.
2009. Synthesis, solution structure and phyla-selectivity of a spider {delta}-toxin that slows inactivation of specific voltage-gated sodium channel subtypes Journal of Biological Chemistry, 284, 24568-24582.
Corzo,G. Prochnicka-Chalufour,A. Garcia,B.I. Possani,L.D. Delepierre,M.
2009. Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus Biochimica et Biophysica Acta-Proteins and Proteomics, 1794, 1591-1598.
Hernandez-Salgado,K. Estrada,G. Olvera,A. Coronas,F.I. Possani,L.D. Corzo,G.
2009. Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus Immunology Letters, 125, 93-99.
Corzo,G. Bernard,C. Clement,H. Villegas,E. Bosmans,F. Tytgat,J. Possani,L.D. Darbon,H. Alagon,A.
2009. Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2 Biochimica et Biophysica Acta (BBA), 1794, 1190-1196.
Prestipino,G. Corzo,G. Romeo,S. Murgia,A.R. Zanardi,I. Gurrola,G. Possani,L.D.
2009. Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells Toxicology Letters, 187, 1-9.
Hernandez-Campuzano,B. Suarez,R. Lina,L. Hernandez,V. Villegas,E. Corzo,G. Iturriaga,G.
2009. Expression of a spider venom peptide in transgenic tobacco confers insect resistance Toxicon, 53, 122-128.
Corzo,G. Papp,F. Varga,Z. Barraza,O. Espino-Solis,P.G. Rodriguez de la Vega,R.C. Gaspar,R. Panyi,G. Possani,L.D.
2008. A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus Biochemical Pharmacology, 76, 1142-1154.
Abdel-Mottaleb,Y. Corzo,G. Martin-Eauclaire,M.F. Satake,H. Ceard,B. Peigneur,S. Nambaru,P. Bougis,P.E. Possani,L.D. Tytgat,J.
2008. A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K(+) channels Biochemical Pharmacology, 76, 805-815.
Corzo,G. Diego-Garcia,E. Clement,H. Peigneur,S. Odell,G. Tytgat,J. Possani,L.D. Alagon,A.
2008. An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera Peptides, 29, 1901-1908.
Villegas,E. Adachi-Akahane,S. Bosmans,F. Tytgat,J. Nakajima,T. Corzo,G.
2008. Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels Toxicon, 52, 228-236.
Romeo,S. Corzo,G. Vasile,A. Satake,H. Prestipino,G. Possani,L.D.
2008. A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K(+) channels responsible for the I(A) currents in cerebellum granular cells Biochim Biophys Acta General Subjects, 1780, 750-755.
Estrada,G. Garcia,B.I. Schiavon,E. Ortiz,E. Cestele,S. Wanke,E. Possani,L.D. Corzo,G.
2007. Four disulfide-bridged scorpion beta neurotoxin CssII: Heterologous expression and proper folding in vitro Biochimica et Biophysica Acta (BBA), 1770, 1161-1168.
Karbat,I. Kahn,R. Cohen,L. Ilan,N. Gilles,N. Corzo,G. Froy,O. Gur,M. Albrecht,G. Heinemann,S.H. Gordon,D. Gurevitz,M.
2007. The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail Febs Journal, 274, 1918-1931.
Estrada,G. Villegas,E. Corzo,G.
2007. Spider venoms: a rich source of acylpolyamines and peptides as new leads for CNS drugs Natural Product Reports, 24, 145-161.
Corzo,G. Sabo,J.K. Bosmans,F. Billen,B. Villegas,E. Tytgat,J. Norton,R.S.
2007. Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels Journal of Biological Chemistry, 282, 4643-4652.
Nomura,K. Corzo,G.
2006. The effect of binding of spider-derived antimicrobial peptides, oxyopinins, on lipid membranes Biochimica Et Biophysica Acta-Biomembranes, 1758, 1475-1482.
Prochnicka-Chalufour,A. Corzo,G. Satake,H. Martin-Eauclaire,M.F. Murgia,A.R. Prestipino,G. D'Suze,G. Possani,L.D. Delepierre,M.
2006. Solution Structure of Discrepin, a New K(+)-Channel Blocking Peptide from the alpha-KTx15 Subfamily(,) Biochemistry, 45, 1795-1804.
Nomura,K. Ferrat,G. Nakajima,T. Darbon,H. Iwashita,T. Corzo,G.
2005. Induction of morphological changes in model lipid membranes and the mechanism of membrane disruption by a large scorpion-derived pore-forming peptide Biophysical Journal, 89, 4067-4080.
Villegas,E. Corzo,G.
2005. Pore-forming peptides from spiders Toxin Reviews, 24, 345-357.
Zeng,X.C. Corzo,G. Hahin,R.
2005. Scorpion venom peptides without disulfide bridges IUBMB Life, 57, 13-21.
Ferrat,G. Bosmans,F. Tytgat,J. Pimentel,C. Chagot,B. Gilles,N. Nakajima,T. Darbon,H. Corzo,G.
2005. Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel Proteins, 59, 368-379 * .
Corzo,G. Escoubas,P. Villegas,E. Karbat,I. Gordon,D. Gurevitz,M. Nakajima,T. Gilles,N.
2005. A Spider Toxin That Induces a Typical Effect of Scorpion alpha-Toxins but Competes with beta-Toxins on Binding to Insect Sodium Channels Biochemistry, 44, 1542-1549.
Chagot,B. Pimentel,C. Dai,L. Pil,J. Tytgat,J. Nakajima,T. Corzo,G. Darbon,H. Ferrat,G.
2005. An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochemical Journal, 388, 263-271.
Belokoneva,O.S. Satake,H. Mal'tseva,E.L. Pal'mina,N.P. Villegas,E. Nakajima,T. Corzo,G.
2004. Pore formation of phospholipid membranes by the action of two hemolytic arachnid peptides of different size Biochimica Et Biophysica Acta-Biomembranes, 1664, 182-188.
Nomura,K. Corzo,G. Nakajima,T. Iwashita,T.
2004. Orientation and Pore-forming Mechanism of a Scorpion Pore- forming Peptide Bound to Magnetically Oriented Lipid Bilayers Biophysical Journal, 87, 2497-2507.
Yamaji,N. Horikawa M Corzo,G. Naoki,H. Haupt,J. Nakajima,T. Iwashita,T.
2004. Structure and enantioselective synthesis of polyamine toxin MG30 from the venom of the spider Macrothele gigas Tetrahedron Letters, 45, 5371-5373 * .
Satake,H. Villegas,E. Oshiro,N. Terada,K. Shinada,T. Corzo,G.
2004. Rapid and efficient identification of cysteine-rich peptides by random screening of a venom gland cDNA library from the hexathelid spider Macrothele gigas Toxicon, 44, 149-156 * .
Wakamiya,T. Kinoshita,T. Hattori,Y. Yamaguchi,Y. Naoki,H. Corzo,G. Nakajima,T.
2004. Study on the structure activity relationships of NPTX-594, a spider toxin belonging to the type-B acylpolyamine structure Bulletin of the Chemical Society of Japan, 77, 331-340 * .
Cohen,L. Karbat,I. Gilles,N. Froy,O. Corzo,G. Angelovici,R. Gordon,D. Gurevitz,M.
2004. Dissection of the functional surface of an anti-insect excitatory toxin illuminates a putative "hot spot" common to all scorpion beta-toxins affecting Na+ channels Journal of Biological Chemistry, 279, 8206-8211 * .
Bernard,C. Corzo,G. Adachi-Akahane,S. Foures,G. Kanemaru,K. Furukawa,Y. Nakajima,T. Darbon,H.
2004. Solution structure of ADO1, a toxin extracted from the saliva of the assassin bug, Agriosphodrus dohrni Proteins: Structure, Function and Genetics, 54, 195-205 * .
Chagot,B. Escoubas,P. Villegas,E. Bernard,C. Ferrat,G. Corzo,G. Lazdunski,M. Darbon,H.
2004. Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus Protein Science, 13, 1197-1208 * .
Nakajima,T. Naoki,H. Corzo,G. Li,D. Hisada,M. Escoubas,P. Yamaji,N. Nagai,H. Yasuda,A. Andriantsiferana,M. Haupt,J. Ohshiro,N.
2003. A trial of mass spectrometric characterization of femto-molar amount from subtropical islands Journal Of Toxicology-Toxin Reviews, 22, 509-520 [Correction 23 (4) 555-556] * .
Shinada,T. Nakagawa,Y. Hayashi,K. Corzo,G. Nakajima,T. Ohfune,Y.
2003. Synthesis and paralytic activities of squaryl amino acid-containing polyamine toxins Amino Acids, 24, 293-301 * .
Corzo,G. Gilles,N. Satake,H. Villegas,E. Dai,L. Nakajima,T. Haupt,J.
2003. Distinct primary structures of the major peptide toxins from the venom of the spider Macrothele gigas that bind to sites 3 and 4 in the sodium channel FEBS Letters, 547, 43-50 * .
Corzo,G. Escoubas,P.
2003. Pharmacologically active spider peptide toxins Cellular and Molecular Life Sciences, 60, 2409-2426 * .
Belokoneva,O.S. Villegas,E. Corzo,G. Dai,L. Nakajima,T.
2003. The hemolytic activity of six arachnid cationic peptides is affected by the phosphatidylcholine-to-sphingomyelin ratio in lipid bilayers Biochimica Et Biophysica Acta-Biomembranes, 1617, 22-30 * .
Escoubas,P. Corzo,G. Whiteley,B.J. Celerier,M.L. Nakajima,T.
2002. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and high-performance liquid chromatography study of quantitative and qualitative variation in tarantula spider venoms Rapid Communications in Mass Spectrometry, 16, 403-413 * .
Corzo,G. Villegas,E. Gomez-Lagunas,F. Possani,L.D. Belokoneva,O.S. Nakajima,T.
2002. Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins Journal of Biological Chemistry, 277, 23627-23637.
Dai,L. Corzo,G. Naoki,H. Andriantsiferana,M. Nakajima,T.
2002. Purification, structure-function analysis, and molecular characterization of novel linear peptides from scorpion Opisthacanthus madagascariensis Biochemical and Biophysical Research Communications, 293, 1514-1522 * .
Corzo,G. Villegas,E. Nakajima,T.
2001. Isolation and structural characterization of a peptide from the venom of scorpion with toxicity towards invertebrates and vertebrates Protein And Peptide Letters, 8, 385-393 * .
Corzo,G. Villegas,E. Lee,H.S. Nakajima,T.
2001. Detection and purification of insecticidal peptides from scorpions and spiders: A rapid method for their isolation from their crude venoms using MALDI-TOF-MS analysis Protein And Peptide Letters, 8, 375-383 * .
Corzo,G. Adachi-Akahane,S. Nagao,T. Kusui,Y. Nakajima,T.
2001. Novel peptides from assassin bugs (Hemiptera: Reduviidae): isolation, chemical and biological characterization FEBS Letters, 499, 256-261 * .
Dai,L. Yasuda,A. Naoki,H. Corzo,G. Andriantsiferana,M. Nakajima,T.
2001. IsCT, a novel cytotoxic linear peptide from scorpion Opisthacanthus madagascariensis Biochemical and Biophysical Research Communications, 286, 820-825 * .
Corzo,G. Escoubas,P. Villegas,E. Barnham,K.J. He,W. Norton,R.S. Nakajima,T.
2001. Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator Biochemical Journal, 359, 35-45 * .
Bernard,C. Corzo,G. Mosbah,A. Nakajima,T. Darbon,H.
2001. Solution structure of Ptu1, a toxin from the assassin bug Peirates turpis that blocks the voltage-sensitive calcium channel N-type Biochemistry, 40, 12795-12800 * .
Corzo,G. Escoubas,P. Stankiewicz,M. Pelhate,M. Kristensen,C.P. Nakajima,T.
2000. Isolation, synthesis and pharmacological characterization of delta-palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae) European Journal of Biochemistry, 267, 5783-5795 * .
Escoubas,P. Diochot,S. Corzo,G.
2000. Structure and pharmacology of spider venom neurotoxins Biochimie, 82, 893-907 * .
Corzo,G. Revah,S.
1999. Production and characteristics of the lipase from Yarrowia lipolytica 681 Bioresource Technology, 70, 173-180 * .
Corzo,G. Gilliland,S.E.
1999. Measurement of bile salt hydrolase activity from Lactobacillus acidophilus based on disappearance of conjugated bile salts Journal of Dairy Science, 82, 466-471 * .
Corzo,G. Gilliland,S.E.
1999. Bile salt hydrolase activity of three strains of Lactobacillus acidophilus Journal of Dairy Science, 82, 472-480 * .
Escoubas,P. Chamot-Rooke,J. Stocklin,R. Whiteley,B.J. Corzo,G. Genet,R. Nakajima,T.
1999. 3.0.CO;2-7> A comparison of matrix-assisted laser desorption/ionization time-of-flight and liquid chromatography electrospray ionization mass spectrometry methods for the analysis of crude tarantula venoms in the Pterinochilus group Rapid Communications in Mass Spectrometry, 13, 1861-1868 * .
Escoubas,P. Whiteley,B.J. Kristensen,C.P. Celerier,M.L. Corzo,G. Nakajima,T.
1998. 3.3.CO;2-I> Multidimensional peptide fingerprinting by high performance liquid chromatography, capillary zone electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the identification of tarantula venom samples Rapid Communications in Mass Spectrometry, 12, 1075-1084 * .
Yagi,H. Corzo,G. Nakahara,T.
1997. N-acyl amino acid biosynthesis in marine bacterium, Deleya marina Biochimica Et Biophysica Acta-General Subjects, 1336, 28-32 * .
Christen,P. Angeles,N. Corzo,G. Farres,A. Revah,S.
1995. Microbial Lipase Production on a Polymeric Resin Biotechnology Techniques, 9, 597-600 * .
Garcia,F. Villegas,E. Ortiz,E. Corzo,G. 2015. Structural Diversity and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from Spiders en: de Lima,M.E. Spider Venoms. Springer Netherlands. pags. 1-20
Diego-Garcia,E. Cologna,C.T. Cassoli,J.S. Corzo,G. 2015. Spider Transcriptomes from Venom Glands: Molecular Diversity of Ion Channel Toxins and Antimicrobial Peptide Transcripts en: de Lima,M.E. Spider Venoms. Springer Netherlands. pags. 1-20
Cordero,M. Hossain,M.A. Espinoza,N. Obregon,V. Roman,M. Navarro,S. Lina,L. Corzo,G. Villegas,E. 2015. Identifying Insect Protein Receptors Using an Insecticidal Spider Toxin en: de Lima,M.E. Spider Venoms. Springer Netherlands. pags. 405-418
Clement,H. Barraza,G. Herrera,E. Garcia,F. Diego-Garcia,E. Villegas,E. Corzo,G. 2015. Antimicrobial, Insecticides, Analgesics, and Hyaluronidases from the Venom Glands of Brachypelma Spiders en: de Lima,M.E. Spider Venoms. Springer Netherlands. pags. 1-13
Gopalakrishnakone,P. Corzo,G.A. Diego-Garcia,E. de Lima,M.E. 2015. Spider Venoms Dordrecht:. Springer Netherlands.
Clement,H. Barraza,G. Garcia,F. Diego,E. Corzo,G. 2014. El Genero Brachypelma en Mexico y en el Estado de Morelos: Componentes del veneno y aplicaciones en: Diversidad biologica y su importancia cultural del Estado de Morelos. Cuernavaca. Editorial DBCEMor. en prensa
Rodriguez de la Vega,R.C. Corzo,G. Possani,L.D. 2014. Scorpion Venoms as a Platform for Drug Development en: Guccione,S. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. Cambridge. Royal Society of Chemistry. pags. 204-220
D'Suze,G. Corzo Burguete,G. Paniagua Solis,J.F. 2011. Emergencias por Animales Ponzonosos en las Americas Mexico:. Instituto Bioclon.
Corzo,G. Revah,S. Christen,P. 1995. Effect of oxygen on the ethyl acetate production from continuous ethanol stream by Candida utilis in submerged cultures en: Charalambous,G. Developments in Food Science. Elsevier. pags. 1141-1154 *
(error para baltzar)
Otras Publicaciones Corzo,G. Arenas,I. Corrales-Garcia,L. Ibarra,M. Callejas,A. Santana,F. Rodriguez,A. Villegas,E.
2019. Peptidos antimicrobianos, una alternativa al uso de antibioticos convencionales Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 18, 17-18.
Bondarenko,O. Corzo,G. Santana,F.L. del Rio-Portilla,F. Darszon,A. Lopez-Gonzalez,I.
2019. Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca2+ currents bioRxiv, Preprint posted March 23, 2019. [Publicado Febs Letters 2019], 586297.
de la Rosa-Hernandez,G. Corzo-Burguete,G.
2018. Inmunógenos recombinantes y su aplicación en antivenenos.Hypatia, 58, .
Corzo-Burguete,G. Alagon-Cano,A. Clement-Carretero,H. Jurado-Reyes,S.M. Herrera-Herrera,E.
2014. Los venenos de tarántulas y la absorción de medicinas en nuestro cuerpo Hypatia, 48, .
Rodriguez-Solis,A.J. Villegas-Villarreal,E.C. Corzo-Burguete,G.
2014. Venenos arácnidos: su sorprendente poder insecticida y su rara capacidad antibiótica Revista Digital Universitaria, 15, Art 85.
Jurado-Reyes,S.M. Garcia-Garcia,F. Corzo-Burguete,G.
2014. De la charca al laboratorio Hypatia, 47, .
Corzo,G.
2011. Determinantes Moleculares de las Neurotoxinas de Arácnidos Implicados en la Unión a los Canales de Sodio Dependientes de Voltaje Mensaje Bioquimico, 35, 131-142.
Alagon-Cano,A. Corzo,G. Clement-Carretero,H. Garcia-Garcia,F.
2010. Arañas: venenos con potencial biotecnológico. Hypatia, 33, .
Patentes Clement, H., García-Corrales, L.L., Bolaños, D., Villegas, E., Corzo, G., 2019 Inmunógenos recombinantes para la producción de anticuerpos contra enzimas tóxicas y como antiveneno de vipéridos.UNAM México. (en trámite)
Clement, H., García-Corrales, L.L., Villegas, E., Corzo, G., 2019 Inmunógenos recombinantes para la producción de anticuerpos contra enzimas de vipéridos.UNAM México. (en trámite)
Estrada, G., Guillén, F., Arenas, I., Corzo, G., 2018 Defensina recombinante J1-1 de chile y su uso como antibiótico.UNAM México. (en trámite)
De la Rosa, G., García-Corrales, L.L., Alagón, A., Corzo, G., 2016 Inmunógenos recombinantes para la producción de antivenenos contra el veneno de elápidos del género Micrurus.UNAM México. (en trámite)
Possani, L.D., Quintero, V., Gonzalez, L., Jiménez-Vargas, J.M., Ortiz, E., Corzo, G., Becerril, B., 2016 Composición farmacéutica de proteínas híbridas recombinantes capaces de generar anticuerpos neutralizantes en contra del veneno de alacranes.UNAM México. (en trámite)
Corzo, G., Garcia, F., Olamendi, T., Sandoval, G., 2015 Proteina analgésica aislada de la secreción de la rana Trachycephalous venulosus.
I. Arenas, R. Rodríguez, Possani, L.D., O. Walls, Corzo, G., 2015 Actividad antimicrobiana "in vitro" de la combinación de péptidos antibiocidas de alacrán con antibióticos de uso común.UNAM Oficina de Patentes Mexico. (en trámite)
Ortiz, E., Ramírez-Carreto, S., Jiménez-Vargas, J.M., Corzo, G., Possani, L.D., 2015 Péptidos del alacrán Vaejovispunctatus como antibióticos contra Mycobacterium tuberculosis y otras bacterias y levaduras patógenas.
A. Rodríguez, E. Villegas, Corzo, G., 2014 Uso de péptidos sintéticos como antibióticos contra mycobacterium tuberculosis y otras bacterias patógenas.
L.L. García-Corrales, A. Rodríguez, Corzo, G., 2013 Uso de péptidos recombinantes y sintéticos como antibióticos contra Mycobacterium tuberculosis y otras bacterias patógenas.
Barraza, G. , Clement, H. , Corzo. G. 2011 Un nuevo péptido analgésico proveniente del veneno de la araña Brachypelma verdezy.UNAM México. (en trámite)
Corzo, G., Garcia, F. , Possani. L.D, Villegas, E. 2011 Uso de un péptido antibiótico proveniente del veneno del alacrán Centruroides suffusus suffusus y sus composiciones farmacéuticas obtenidas con antibióticos comerciales.UNAM México.
Corzo, G., Estrada. G. , Hernandez, K. , Garcia B.I. , Possani. L.D 2011 Variantes recombinantes de una toxina del veneno del alacrán Centruroides sufussus sufussus para la producción de antivenenos contra el veneno de alacranes del género Centruroides.UNAM México.
G.A.Corzo-Burguete, G. Estrada-Tapia, K. Hernández-Salgado, B. I. García-Gómez y L. D. Possani P 2008 Inmunógenos recombinantes para la producción de antivenenos contra el veneno de alacranes del género Centruroides .UNAM México. (en trámite)
G. Corzo P. Escoubas 2002 Insecticidal peptides and methods for use of same.
G. Corzo P. Escoubas 2002 Insecticidal peptides and methods for use of same.
G. Corzo T. Nakajima 2002 Novel assassin bug peptides having calcium channel.
G. Corzo E. Villegas y T Nakajima 2001 Antimicrobial peptides from venom of scorpions.
* Indica publicación con otra institución de adscripción
