IBT-UNAM : Dra. Maria Brenda Valderrama Blanco
Dra. Maria Brenda Valderrama Blanco
Secretaría de Vinculación
email: brenda @ibt.unam.mx
Teléfonos
Oficina +52 (777) 329-1616 red UNAM 27616 Laboratorio +52 (777) 329-1610 red UNAM 27610
- Licenciatura: Investigacion Biomedica Basica, UNAM (1986)
Estudiantes Tec. Moises Geovanny Cruz
Edgar Abraham Trejo
Rodolfo Guillermo Valle "Caracterización de los intermediarios formados por la Zo peroxidasa luego de cumplir su ciclo de catálisis"
Publicaciones recientes
Armenta-Medina,D. Diaz de Leon-Castaneda Valderrama-Blanco,B.
2020. Bioinformatics in Mexico: A diagnostic from the academic perspective and recommendations for a public policy PLoS ONE, 15, e0243531.
Valderrama,B. Paredes-Valdez,G. Rodriguez,R. Romero-Guido,C. Martinez,F. Martinez-Romero,J. Guerrero-Galvan,S. Mendoza-Herrera,A. Folch-Mallol,J.L.
2016. Assessment of non-cultured aquatic fungal diversity from different habitats in Mexico Revista Mexicana de Biodiversidad, 87, 18-28.
Gasteazoro,F. Simaan,A.J. Tinoco-Valencia,R. Valderrama,B.
2015. Validation of a General Method for Activity Estimation of Cyanide Evolving Oxidoreductases Analytical Biochemistry, 471, 44-50.
Castro-Acosta,R.M. Rodriguez-Limas,W.A. Valderrama,B. Ramirez,O.T. Palomares,L.A.
2014. Effect of metal catalyzed oxidation in recombinant viral protein assemblies Microbial Cell Factories, 13, 25.
Hernandez-Montes,G. Arguello,J.M. Valderrama,B.
2012. Evolution and diversity of periplasmic proteins involved in copper homeostasis in gamma proteobacteria BMC Microbiology, 12, 249.
Bello,M. Valderrama,B. Serrano-Posada,H. Rudino-Pinera,E.
2012. Molecular Dynamics of a Thermostable Multicopper Oxidase from Thermus thermophilus HB27: Structural Differences between the Apo and Holo Forms PLoS ONE, 7, e40700.
De la Mora,E. Lovett,J.E. Blanford,C.F. Garman,E.F. Valderrama,B. Rudino-Pinera,E.
2012. Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase Acta Crystallographica Section D: Biological Crystallography, 68, 564-577.
Serrano-Posada,H. Valderrama,B. Stojanoff,V. Rudino-Pinera,E.
2011. Thermostable multicopper oxidase from Thermus thermophilus HB27: crystallization and preliminary X-ray diffraction analysis of apo and holo forms Acta Crystallographica Section F: Structural Biology Communications, 67, 1595-1598.
Gil-Rodriguez,P. Valderrama,B.
2009. An optimized procedure for the purification of Zo peroxidase (ZoPrx), a low abundance peroxidase from Japanese radish roots International Journal of Plant Physiology and Biochemistry, 1, 9-12.
Vite-Vallejo,O. Palomares,L.A. Dantan-Gonzalez,E. Ayala-Castro,H.G. Martinez-Anaya,C. Valderrama,B. Folch-Mallol,J.
2009. The role of N-glycosylation on the enzymatic activity of a Pycnoporus sanguineus laccase Enzyme and Microbial Technology, 45, 233-239.
Saab-Rincon,G. Valderrama,B.
2009. Protein engineering of redox-active enzymes Antioxidants and Redox Signaling, 11, 167-192.
Ito-Kuwa,S. Nakamura,K. Valderrama,B. Aoki,S. Vidotto,V. Osafune,T.
2008. Diversity of laccase among Cryptococcus neoformans serotypes Microbiology and Immunology, 52, 492-498.
Gil-Rodriguez,P. Ferreira-Batista,C. Vazquez-Duhalt,R. Valderrama,B.
2008. A novel heme peroxidase from Raphanus sativus intrinsically resistant to hydrogen peroxide Engineering in Life Sciences, 8, 286-296.
Valderrama,B. Garcia-Arellano,H. Giansanti,S. Baratto,M.C. Pogni,R. Vazquez-Duhalt,R.
2006. Oxidative stabilization of iso-1-cytochrome c by redox-inspired protein engineering FASEB Journal, 20, 1233-1235.
Valderrama,B. Vazquez-Duhalt,R.
2005. Electron-balance during the oxidative self-inactivation of cytochrome c Journal Of Molecular Catalysis B-Enzymatic, 35, 41-44.
Jimenez-Juarez,N. Roman-Miranda,R. Baeza,A. Sanchez-Amat,A. Vazquez-Duhalt,R. Valderrama,B.
2005. Alkali and halide-resistant catalysis by the multipotent oxidase from Marinomonas mediterranea Journal of Biotechnology, 117, 73-82.
Pogni,R. Baratto,M.C. Giansanti,S. Teutloff,C. Verdin,J. Valderrama,B. Lendzian,F. Lubitz,W. Vazquez-Duhalt,R. Basosi,R.
2005. Tryptophan-Based Radical in the Catalytic Mechanism of Versatile Peroxidase fromBjerkandera adusta Biochemistry, 44, 4267-4274.
Necochea,R. Valderrama,B. Diaz-Sandoval,S. Folch-Mallol,J.L. Vazquez-Duhalt,R. Iturriaga,G.
2005. Phylogenetic and biochemical characterisation of a recombinant laccase from Trametes versicolor Fems Microbiology Letters, 244, 235-241.
Jauregui,J. Valderrama,B. Albores,A. Vazquez-Duhalt,R.
2003. Microsomal transformation of organophosphorus pesticides by white rot fungi Biodegradation, 14, 397-406.
Valderrama,B. Oliver,P. Medrano-Soto,A. Vazquez-Duhalt,R.
2003. Evolutionary and structural diversity of fungal laccases Antonie Van Leeuwenhoek, 84, 289-299.
Medina,G. Juarez,K. Valderrama,B. Soberon-Chavez,G.
2003. Mechanism of Pseudomonas aeruginosa RhlR Transcriptional Regulation of the rhlAB Promoter Journal of Bacteriology, 185, 5976-5983.
Arreola,R. Valderrama,B. Morante,M.L. Horjales,E.
2003. Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study FEBS Letters, 551, 63-70.
Garcia-Arellano,H. Valderrama,B. Saab-Rincon,G. Vazquez-Duhalt,R.
2002. High temperature biocatalysis by chemically modified cytochrome C Bioconjugate Chemistry, 13, 1336-1344.
Vazquez-Duhalt,R. Torres,E. Valderrama,B. Le Borgne,S.
2002. Will biochemical catalysis impact the petroleum refining industry? Energy & Fuels, 16, 1239-1250.
Valderrama,B. Ayala,M. Vazquez-Duhalt,R.
2002. Suicide inactivation of peroxidases and the challenge of engineering more robust enzymes Chemistry and Biology, 9, 555-565.
Castillo,A. Taboada,H. Mendoza,A. Valderrama,B. Encarnacion,S. Mora,J.
2000. Role of GOGAT in carbon and nitrogen partitioning in Rhizobium etli Microbiology-Uk, 146, 1627-1637 * .
Barrios,H. Valderrama,B. Morett,E.
1999. Compilation and analysis of sigma(54)-dependent promoter sequences Nucleic Acids Research, 27, 4305-4313.
Grande,R.A. Valderrama,B. Morett,E.
1999. Suppression analysis of positive control mutants of NifA reveals two overlapping promoters for Klebsiella pneumoniae rpoN Journal of Molecular Biology, 294, 291-298.
Ramirez,M. Valderrama,B. Arredondo-Peter,R. Soberon,M. Mora,J. Hernandez,G.
1999. Rhizobium etli genetically engineered for the heterologous expression of Vitreoscilla sp hemoglobin: Effects on free- living and symbiosis Molecular Plant-Microbe Interactions, 12, 1008-1015.
Mendoza,A. Valderrama,B. Leija,A. Mora,J.
1998. NifA-dependent expression of glutamate dehydrogenase in Rhizobium etli modifies nitrogen partitioning during symbiosis Molecular Plant-Microbe Interactions, 11, 83-90 * .
Valderrama,B. Davalos,A. Girard,L. Morett,E. Mora,J.
1996. Regulatory proteins and cis-acting elements involved in the transcriptional control of Rhizobium etli reiterated nifH genes Journal of Bacteriology, 178, 3119-3126.
Girard,L. Valderrama,B. Palacios,R. Romero,D. Davila,G.
1996. Transcriptional activity of the symbiotic plasmid of Rhizobium etli is affected by different environmental conditions Microbiology-Uk, 142, 2847-2856 * .
Libros y capítulos recientes Rodriguez-Hernandez,R. Valderrama-Blanco,M.B. Folch-Mallol,J.L. 2020. http://biodiversidad.morelos.gob.mx/biodiversidad/libro-estudio-de-estado-2 en: Biodiversidad en Morelos. Estudio de estado 2, vol 2. Mexico. CONABIO. pags. 397-400
Valderrama-Blanco,B. 2019. Estrategias para impulsar el desarrollo tecnológico: una asignatura pendiente para México en: Oropeza-Garcia,A. Desarrollo Industrial 2050. Hacia una industria del futuro. Mexico. IIJ-UNAM y Instituto para el Desarrollo Industrial y el Crecimiento Económico. pags. 121-138
Valderrama,B. 2019. Megaciencia. Una asignatura pendiente para México en: Moreno,M. La Fuente de Luz de Sincrotrón Mexicana. Un proyecto para la transformación de la ciencia, la tecnología y la innovación. Ciudad de Mexico. Fondo de Cultura Económica. pags. 153-184
Valderrama,B. Rodriguez-Alonso,G. Pogni,R. 2011. Transfer of free radicals between proteins and membrane lipids: implications for aquatic biology en: Zeneteno-Savin,T. Oxidative stress in aquatic ecosystems. Wiley-Blackwell. pags. 224-235
Valderrama,B. 2010. Deactivation of hemeperoxidases by hydrogen peroxide: Focus on compound III en: *maa Biocatalysis based on heme peroxidases . Peroxidases as Potential Industrial Biocatalysts. Springer. pags. 291-314
Valderrama,B. 2004. Bacterial hydrocarbon biosynthesis revisited en: Quintero-Ramirez,R. Petroleum Biotechnology: Developments and Perspectives. Elsevier. pags. 373-384
Vazquez-Duhalt,R. Garcia,H. Valderrama,B. 2003. Chemical and genetic design of cytochrome c as biocatalyst en: VI International Plant Peroxidase Symposium. Espana.
Valderrama,B. Ayala,M. Vazquez-Duhalt,R. 2003. Ambiente, energía y la nueva industria. en: *agustin Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII. Mexico,D.F.. El Colegio Nacional. pags. 67-91
Gosset,G. Bolivar,F. Soberon,X. Lopez-Munguia,A. Valderrama,B. Ayala,M. Vazquez,R. Ramirez,O.T. Alagon,A. Possani,L.D. 2003. Fronteras de la Biología en los Inicios del Siglo XXI. Módulo VII: Ingeniería Celular, Biodiversidad e Industria. Mexico, D.F.: El Colegio Nacional.
Valderrama,B. 2001. Microbiologia del petroleo y sus derivados en: Martinez-Romero,E. Microbios en linea. Coordinacion de la Investigacion Cientifica. pags. 19-35
Jauregui,J. Valderrama,B. Vazquez-Duhalt,R. 2001. 6 en: Leeson,A. Ex situ biological treatment technologies. Columbus, Ohio. Battelle Press. pags. 17-25
Lara,M. Ortega,J.L. Valderrama,B. 1987. Localization of the Glutamine Synthetase Polypeptides in Phaseolus Root Nodules en: Brisson,N. Molecular genetics of plant-microbe interactions: Proceedings of the Third International Symposium on the Molecular Genetics of Plant-Microbe Associations, Montréal, Québec, Canada, July 27-31, 1986. Dordrecht. Springer Netherlands. pags. 142-144 *
Otras Publicaciones Valderrama-Blanco,M.B. Sanchez-Flores,F.A. Burguete-Garcia,A.I. Orozco-Nunez,E.
2020. La colaboración Academia-Gobierno como un elemento importante para la atención temprana de la pandemia de COVID-19 en Cuernavaca Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 22, 18-22.
* Indica publicación con otra institución de adscripción
Investigador Adscrito Temporalmente al Departamento