IBT-UNAM : Dr. Baltazar Becerril Lujan
- Licenciatura: en Biología, Fac. de Ciencias-UNAM (1979)
Estudiantes Salvador Salgado
M.C. Hugo Valencia
M.C. Alejandra Galiote
Ilse Viridiana Gomez
M.C. Guillermo Fernandez
Publicaciones recientes
Lopez-Giraldo,A.E. Olamendi-Portugal,T. Riano-Umbarila,L. Becerril,B. Possani,L.D. Delepierre,M. Rio-Portilla,F.D.
2020. The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus Toxicon, 184, 158-166.
Gomez-Ramirez,I.V. Riano-Umbarila,L. Olamendi-Portugal,T. Restano-Cassulini,R. Possani,L.D. Becerril,B.
2020. Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico Toxicon, 184, 10-18.
Riano-Umbarila,L. Rojas-Trejo,V.M. Romero-Moreno,J.A. Costas,M. Utrera-Espindola,I. Olamendi-Portugal,T. Possani,L.D. Becerril,B.
2020. Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies Molecular Immunology, 122, 141-147.
Delgado-Prudencio,G. Possani,L.D. Becerril,B. Ortiz,E.
2019. The Dual alpha-Amidation System in Scorpion Venom Glands Toxins (Basel), 11, 425.
Ruiz-Zamora,R.A. Guillaume,S. Al-Hilaly,Y.K. Al-Garawi,Z. Rodriguez-Alvarez,F.J. Zavala-Padilla,G. Perez-Carreon,J.I. Rodriguez-Ambriz,S.L. Herrera,G.A. Becerril-Lujan,B. Ochoa-Leyva,A. Melendez-Zajgla,J. Serpell,L. Del Pozo-Yauner,L.
2019. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation Scientific Reports, 9, 3123.
Riano-Umbarila,L. Gomez-Ramirez,I.V. Ledezma-Candanoza,L.M. Olamendi-Portugal,T. Rodriguez-Rodriguez,E.R. Fernandez-Taboada,G. Possani,L.D. Becerril,B.
2019. Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms Toxins (Basel), 11, 32.
Carcamo-Noriega,E.N. Olamendi-Portugal,T. Restano-Cassulini,R. Rowe,A. Uribe-Romero,S.J. Becerril,B. Possani,L.D.
2018. Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona Archives of Biochemistry and Biophysics, 638, 52-57.
Luna-Martinez,O.D. Hernandez-Santoyo,A. Villalba-Velazquez,M.I. Sanchez-Alcala,R. Fernandez-Velasco,D.A. Becerril,B.
2017. Stabilizing an amyloidogenic lambda6 light chain variable domain Febs Journal, 294, 3702-3717.
Riano-Umbarila,L. Rodriguez-Rodriguez,E.R. Santibanez-Lopez,C.E. Guereca,L. Uribe-Romero,S.J. Gomez-Ramirez,I.V. Carcamo-Noriega,E.N. Possani,L.D. Becerril,B.
2017. Updating knowledge on new medically important scorpion species in Mexico Toxicon, 138, 130-137.
Olamendi-Portugal,T. Restano-Cassulini,R. Riano-Umbarila,L. Becerril,B. Possani,L.D.
2017. Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion centruroides limpidus Peptides, 87, 34-40.
Luna-Martinez,O.D. Vidal-Limon,A. Villalba-Velazquez,M.I. Sanchez-Alcala,R. Garduno-Juarez,R. Uversky,V.N. Becerril,B.
2016. Simple approach for ranking structure determining residues PeerJ, 4, e2136.
Rodriguez-Rodriguez,E.R. Olamendi-Portugal,T. Serrano-Posada,H. Arredondo-Lopez,J.N. Gomez-Ramirez,I. Fernandez-Taboada,G. Possani,L.D. Vega,G.A. Riano-Umbarila,L. Becerril,B.
2016. Broadening the neutralizing capacity of a family of antibody fragments against different toxins from Mexican scorpions Toxicon, 119, 52-63.
Olamendi-Portugal,T. Bartok,A. Zamudio-Zuniga,F. Balajthy,A. Becerril,B. Panyi,G. Possani,L.D.
2016. Isolation, chemical and functional characterization of several new K-channel blocking peptides from the venom of the scorpion Centruroides tecomanus Toxicon, 115, 1-12.
Riano-Umbarila,L. Ledezma-Candanoza,L.M. Serrano-Posada,H. Fernandez-Taboada,G. Olamendi-Portugal,T. Rojas-Trejo,S. Gomez-Ramirez,I.V. Rudino-Pinera,E. Possani,L.D. Becerril,B.
2016. Optimal neutralization of Centruroides noxius venom is understood through a structural complex between two antibody fragments and the Cn2 toxin Journal of Biological Chemistry, 291, 1619-1630.
Ramirez-Carreto,S. Jimenez-Vargas,J.M. Rivas-Santiago,B. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2015. Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity Peptides, 73, 51-59.
Zuniga-Navarrete,F. Gomez,I. Pena,G. Amaro,I. Ortiz,E. Becerril,B. Ibarra,J.E. Bravo,A. Soberon,M.
2015. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12 Insect Biochemistry and Molecular Biology, 59, 50-57.
Quintero-Hernandez,V. Ramirez-Carreto,S. Romero-Gutierrez,M.T. Valdez-Velazquez,L.L. Becerril,B. Possani,L.D. Ortiz,E.
2015. Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus PLoS ONE, 10, e0117188.
Villalba,M.I. Canul-Tec,J.C. Luna-Martinez,O.D. Sanchez-Alcala,R. Olamendi-Portugal,T. Rudino-Pinera,E. Rojas,S. Sanchez-Lopez,R. Fernandez-Velasco,D.A. Becerril,B.
2015. Site-directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human lambda3r Light Chains Journal of Biological Chemistry, 290, 2577-2592 [Correction vol 290 p 13039].
Gonzalez-Andrade,M. Becerril-Lujan,B. Sanchez-Lopez,R. Cecena-Alvarez,H. Perez-Carreon,J.I. Ortiz-Suri,E. Fernandez-Velasco,D.A. Del Pozo-Yauner,L.
2013. Mutational and genetic determinants of lambda6 light chain amyloidogenesis Febs Journal, 280, 6173-6183.
Riano-Umbarila,L. Olamendi-Portugal,T. Morelos-Juarez,C. Gurrola,G.B. Possani,L.D. Becerril,B.
2013. A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins Toxicon, 76, 370-376.
Aguilar,M.B. Ortiz,E. Kaas,Q. Lopez-Vera,E. Becerril,B. Possani,L.D. de la Cotera,E.P.
2013. Precursor De13.1 from Conus delessertii defines the novel G gene superfamily Peptides, 41, 17-20.
Rodriguez-Rodriguez,E.R. Ledezma-Candanoza,L.M. Contreras-Ferrat,L.G. Olamendi-Portugal,T. Possani,L.D. Becerril,B. Riano-Umbarila,L.
2012. A Single Mutation in Framework 2 of the Heavy Variable Domain Improves the Properties of a Diabody and a Related Single-Chain Antibody Journal of Molecular Biology, 423, 337-350.
Ramirez-Carreto,S. Quintero-Hernandez,V. Jimenez-Vargas,J.M. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2012. Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae Peptides, 34, 290-295.
Quintero-Hernandez,V. Del Pozo-Yauner,L. Pedraza-Escalona,M. Juarez-Gonzalez,V.R. Alcantara-Recillas,I. Possani,L.D. Becerril,B.
2012. Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: Neutralization capacity versus thermodynamic stability Immunology Letters, 143, 152-160.
Quintero-Hernandez,V. Ortiz,E. Rendon,M.R. Schwartz,E.F. Becerril,B. Corzo,G. Possani,L.D.
2011. Scorpion and spider venom peptides: Gene cloning and peptide expression Toxicon, 58, 644-663.
Amaro,I. Riano-Umbarila,L. Becerril,B. Possani,L.D.
2011. Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion Immunology Letters, 139, 73-79.
Canul-Tec,J.C. Riano-Umbarila,L. Rudino-Pinera,E. Becerril,B. Possani,L.D. Torres-Larios,A.
2011. Structural basis of neutralization of the major toxic component from the scorpion centruroides noxius hoffmann by a human-derived single chain antibody fragment Journal of Biological Chemistry, 286, 20892-20900.
Riano-Umbarila,L. Contreras-Ferrat,G. Olamendi-Portugal,T. Morelos-Juarez,C. Corzo,G. Possani,L.D. Becerril,B.
2011. Exploiting cross-reactivity to neutralize two different scorpion venoms with one single-chain antibody fragment Journal of Biological Chemistry, 286, 6143-6151.
Medecigo,M. Manoutcharian,K. Vasilevko,V. Govezensky,T. Munguia,M.E. Becerril,B. Luz-Madrigal,A. Vaca,L. Cribbs,D.H. Gevorkian,G.
2010. Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody libraries Journal of Neuroimmunology, 223, 104-114.
Hernandez-Santoyo,A. Del Pozo-Yauner,L. Fuentes-Silva,D. Ortiz,E. Rudino-Pinera,E. Sanchez-Lopez,R. Horjales,E. Becerril,B. Rodriguez-Romero,A.
2010. A single mutation at the sheet switch region results in conformational changes favoring lambda6-light-chain fibrillogenesis Journal of Molecular Biology, 396, 280-292.
Espino-Solis,G.P. Riano-Umbarila,L. Becerril,B. Possani,L.D.
2009. Antidotes against venomous animals: State of the art and prospectives Journal of Proteomics, 72, 183-199.
Blancas-Mejia,L.M. Tellez,L.A. Del Pozo-Yauner,L. Becerril,B. Sanchez-Ruiz,J.M. Fernandez-Velasco,D.A.
2009. Thermodynamic and Kinetic Characterization of a Germ Line Human lambda6 Light-Chain Protein: The Relation between Unfolding and Fibrillogenesis Journal of Molecular Biology, 386, 1153-1166.
Pedraza-Escalona,M. Becerril-Lujan,B. Agundis,C. Dominguez-Ramirez,L. Pereyra,A. Riano-Umbarila,L. Rodriguez-Romero,A.
2009. Analysis of B-cell epitopes from the allergen Hev b 6.02 revealed by using blocking antibodies Molecular Immunology, 46, 668-676.
Olamendi-Portugal,T. Batista,C.V. Restano-Cassulini,R. Pando,V. Villa-Hernandez,O. Zavaleta-Martinez-Vargas,A. Salas-Arruz,M.C. de la Vega RC Becerril,B. Possani,L.D.
2008. Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: Novel toxins, their function and phylogeny Proteomics, 8, 1919-1932.
Restano-Cassulini,R. Olamendi-Portugal,T. Zamudio,F. Becerril,B. Possani,L.D.
2008. Two Novel Ergtoxins, Blockers of K(+)-channels, Purified from the Mexican Scorpion Centruroides elegans elegans Neurochemical Research, 33, 1525-1533.
Del Pozo-Yauner,L. Ortiz,E. Sanchez,R. Sanchez-Lopez,R. Guereca,L. Murphy,C.L. Allen,A. Wall,J.S. Fernandez-Velasco,D.A. Solomon,A. Becerril,B.
2008. Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains Proteins, 72, 684-692.
Gutierrez-Gonzalez,L. Muresanu,L. Del Pozo-Yauner,L. Sanchez,R. Guereca,L. Becerril,B. Lucke,C.
2007. 1H, 13C and 15N resonance assignment of 6aJL2(R25G), a highly fibrillogenic λVI light chain variable domain Biomolecular NMR Assignments, 1, 159-161.
Lopez-Vera,E. Aguilar,M.B. Schiavon,E. Marinzi,C. Ortiz,E. Restano-Cassulini,R. Batista,C.V.F. Possani,L.D. Heimer de la Cotera,E.P. Peri,F. Becerril,B. Wanke,E.
2007. Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors Febs Journal, 274, 3972-3985.
Romero-Martinez,R. Curiel-Quesada,E. Becerril-Lujan,B. Flores-Carreon,A. Perez-Torres,A. Taylor,M.L.
2007. Detection of constitutive molecules on Histoplasma capsulatum yeasts through single chain variable antibody fragments displayed in M13 phages Fems Immunology and Medical Microbiology, 50, 77-85.
Quintero-Hernandez,V. Juarez-Gonzalez,V.R. Ortiz-Leon,M. Sanchez,R. Possani,L.D. Becerril,B.
2007. The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies Molecular Immunology, 44, 1307-1315.
Almagro,J.C. Quintero-Hernandez,V. Ortiz-Leon,M. Velandia,A. Smith,S.L. Becerril,B.
2006. Design and validation of a synthetic V(H) repertoire with tailored diversity for protein recognition Journal of Molecular Recognition, 19, 413-422.
Gomez,I. Arenas,I. Benitez,I. Miranda-Rios,J. Becerril,B. Grande,R. Almagro,J.C. Bravo,A. Soberon,M.
2006. Specific epitopes of domains II and IIII of bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in manduca sexta Journal of Biological Chemistry, 281, 34032-34039.
Languren,M. Becerril,B. Cabral,A.R. Fernandez-Altuna,L.E. Pascual,V. Hernandez-Ramirez,D.F. Cabiedes,J.
2006. Characterization of monoclonal anti-beta(2)-glycoprotein-I and anti-prothrombin antibody fragments generated by phage display from a patient with primary antiphospholipid syndrome Journal of Autoimmunity, 26, 57-65.
Del Pozo-Yauner,L. Ortiz,E. Becerril,B.
2006. The CDR1 of the human lambdaVI light chains adopts a new canonical structure Proteins, 62, 122-129.
Aguilar,M.B. Lopez-Vera,E. Ortiz,E. Becerril,B. Possani,L.D. Olivera,B.M. Heimer de la Cotera,E.P.
2005. A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues Biochemistry, 44, 11130-11136.
Olamendi-Portugal,T. Somodi,S. Fernandez,J.A. Zamudio,F.Z. Becerril,B. Varga,Z. Panyi,G. Gaspar,R. Possani,L.D.
2005. Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockage Kv1.3 over IKCa1 K(+) channels of T cells Toxicon, 46, 418-429.
Riano-Umbarila,L. Juarez-Gonzalez,V.R. Olamendi-Portugal,T. Ortiz-Leon,M. Possani,L.D. Becerril,B.
2005. A strategy for the generation of specific human antibodies by directed evolution and phage display Febs Journal, 272, 2591-2601.
Juarez-Gonzalez,V.R. Riano-Umbarila,L. Quintero-Hernandez,V. Olamendi-Portugal,T. Ortiz-Leon,M. Ortiz,E. Possani,L.D. Becerril,B.
2005. Directed Evolution, Phage Display and Combination of Evolved Mutants: A Strategy to Recover the Neutralization Properties of the scFv Version of BCF2 a Neutralizing Monoclonal Antibody Specific to Scorpion Toxin Cn2 Journal of Molecular Biology, 346, 1287-1297.
Manoutcharian,K. Acero,G. Munguia,M.E. Becerril,B. Massieu,L. Govezensky,T. Ortiz,E. Marks,J.D. Cao,C. Ugen,K. Gevorkian,G.
2004. Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1-42 Neurobiology of Disease, 17, 114-121.
Selisko,B. Cosio,G. Garcia,C. Becerril,B. Possani,L.D. Horjales,E.
2004. Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann Toxicon, 43, 43-51.
Batista,C.V. Del Pozo,L. Zamudio,F.Z. Contreras,S. Becerril,B. Wanke,E. Possani,L.D.
2004. Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 803, 55-66.
Corona,M. Coronas,F.V. Merino,E. Becerril,B. Gutierrez,R. Rebolledo-Antunez,S. Garcia,D.E. Possani,L.D.
2003. A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat Biochimica et Biophysica Acta-Proteins and Proteomics, 1649, 58-67.
Rodriguez de la Vega,R.C. Merino,E. Becerril,B. Possani,L.D.
2003. Novel interactions between K(+) channels and scorpion toxins Trends in Pharmacological Sciences, 24, 222-227.
Garcia,C. Calderon-Aranda,E.S. Anguiano,G.A. Becerril,B. Possani,L.D.
2003. Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann Toxicon, 41, 417-427.
O'Connell,D. Becerril,B. Roy-Burman,A. Daws,M. Marks,J.D.
2002. Phage versus phagemid libraries for generation of human monoclonal antibodies Journal of Molecular Biology, 321, 49-56 * .
Huie,M.A. Cheung,M.C. Muench,M.O. Becerril,B. Kan,Y.W. Marks,J.D.
2001. Antibodies to human fetal erythroid cells from a nonimmune phage antibody library Proceedings of the National Academy of Sciences of the United States of America, 98, 2682-2687 * .
Possani,L.D. Merino,E. Corona,M. Bolivar,F. Becerril,B.
2000. Peptides and genes coding for scorpion toxins that affect ion-channels Biochimie, 82, 861-868.
Poul,M.A. Becerril,B. Nielsen,U.B. Morisson,P. Marks,J.D.
2000. Selection of tumor-specific internalizing human antibodies from phage libraries Journal of Molecular Biology, 301, 1149-1161 * .
Selisko,B. Licea,A.F. Becerril,B. Zamudio,F. Possani,L.D. Horjales,E.
1999. 3.0.CO;2-S> Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen Proteins, 37, 130-143.
Possani,L.D. Becerril,B. Delepierre,M. Tytgat,J.
1999. Scorpion toxins specific for Na+-channels European Journal of Biochemistry, 264, 287-300.
Conde,R. Zamudio,F.Z. Becerril,B. Possani,L.D.
1999. Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom FEBS Letters, 460, 447-450.
Becerril,B. Poul,M.A. Marks,J.D.
1999. Toward selection of internalizing antibodies from phage libraries Biochemical and Biophysical Research Communications, 255, 386-393.
Martinez,F. Munoz-Garay,C. Gurrola,G. Darszon,A. Possani,L.D. Becerril,B.
1998. Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels FEBS Letters, 429, 381-384.
Selisko,B. Garcia,C. Becerril,B. Gomez-Lagunas,F. Garay,C. Possani,L.D.
1998. Cobatoxins 1 and 2 from Centruroides noxius Hoffmann constitute a subfamily of potassium-channel-blocking scorpion toxins European Journal of Biochemistry, 254, 468-479.
Garcia,C. Becerril,B. Selisko,B. Delepierre,M. Possani,L.D.
1997. Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann Comparative Biochemistry and Physiology, 116, 315-322.
Zamudio,F.Z. Conde,R. Arevalo,C. Becerril,B. Martin,B.M. Valdivia,H.H. Possani,L.D.
1997. The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator Journal of Biological Chemistry, 272, 11886-11894.
Becerril,B. Marangoni,S. Possani,L.D.
1997. Toxins and genes isolated from scorpions of the genus Tityus Toxicon, 35, 821-835.
Corona,M. Zurita,M. Possani,L.D. Becerril,B.
1996. Cloning and characterization of the genomic region encoding toxin IV-5 from the scorpion Tityus serrulatus Lutz and Mello Toxicon, 34, 251-256.
Becerril,B. Corona,M. Coronas,F.I. Zamudio,F. Calderon-Aranda,E.S. Fletcher,P.L. Martin,B.M. Possani,L.D.
1996. Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus Biochemical Journal, 313, 753-760.
Licea,A.F. Becerril,B. Possani,L.D.
1996. Fab fragments of the monoclonal antibody BCF2 are capable of neutralizing the whole soluble venom from the scorpion Centruroides noxius Hoffmann Toxicon, 34, 843-847.
Martinez,F. Becerril,B. Gurrola,G.B. Martin,B.M. Possani,L.D.
1996. Synthesis and expression of the gene coding for noxiustoxin, a K+ channel-blocking peptide from the venom of the scorpion Centruroides noxius Toxicon, 34, 1413-1419.
Selisko,B. Garcia,C. Becerril,B. Delepierre,M. Possani,L.D.
1996. An insect-specific toxin from Centruroides noxius Hoffmann. cDNA, primary structure, three-dimensional model and electrostatic surface potentials in comparison with other toxin variants European Journal of Biochemistry, 242, 235-242.
Vazquez,A. Tapia,J.V. Eliason,W.K. Martin,B.M. Lebreton,F. Delepierre,M. Possani,L.D. Becerril,B.
1995. Cloning and characterization of the cDNAs encoding Na+ channel-specific toxins 1 and 2 of the scorpion Centruroides noxius Hoffmann Toxicon, 33, 1161-1170.
Becerril,B. Corona,M. Garcia,C. Bolivar,F. Possani,L.D.
1995. Cloning of genes encoding scorpion toxins: An interpretative review Journal Of Toxicology-Toxin Reviews, 14, 339-357.
Vazquez,A. Becerril,B. Martin,B.M. Zamudio,F. Bolivar,F. Possani,L.D.
1993. Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann FEBS Letters, 320, 43-46.
Becerril,B. Vazquez,A. Garcia,C. Corona,M. Bolivar,F. Possam,L.D.
1993. Cloning and characterization of cDNAs that code for Na(+)-channel-blocking toxins of the scorpion Centruroides noxius Hoffmann Gene, 128, 165-171.
Becerril,B. Corona,M. Mejia,M.C. Martin,B.M. Lucas,S. Bolivar,F. Possani,L.D.
1993. The genomic region encoding toxin gamma from the scorpion Tityus serrulatus contains an intron FEBS Letters, 335, 6-8.
Merino,E. Balbas,P. Aarons,S.R. Recillas,F. Becerril,B. Valle,F. Bolivar,F.
1992. Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene Molecular Microbiology, 6, 2175-2182.
Martinez-Medellin,J. Valdes-Lopez,V. Alba Lois,L. Becerril,B. Mayani,H. Mainero,A.
1991. A study of erythropoiesis and iron metabolism in the rabbit in vivo. I. Characterization and limits of the physiological response.Archivos de Investigacion Medica, 22, 309-315.
Gosset,G. Merino,E. Recillas,F. Oliver,G. Becerril,B. Bolivar,F.
1989. Amino acid sequence analysis of the glutamate synthase enzyme from Escherichia coli K-12.Protein sequences & data analysis, 2, 9-16.
Bravo,A. Becerril,B. Mora,J.
1988. Introduction of the Escherichia coli gdhA gene into Rhizobium phaseoli: effect on nitrogen fixation Journal of Bacteriology, 170, 985-988 * .
Riba,L. Becerril,B. Servin-Gonzalez,L. Valle,F. Bolivar,F.
1988. Identification of a functional promoter for the Escherichia coli gdhA gene and its regulation Gene, 71, 233-246.
Merino,E. Becerril,B. Valle,F. Bolivar,F.
1987. Deletion of a repetitive extragenic palindromic (REP) sequence downstream from the structural gene of Escherichia coli glutamate dehydrogenase affects the stability of its mRNA Gene, 58, 305-309.
Oliver,G. Gosset,G. Sanchez-Pescador,R. Lozoya,E. Ku,L.M. Flores,N. Becerril,B. Valle,F. Bolivar,F.
1987. Determination of the nucleotide sequence for the glutamate synthase structural genes of Escherichia coli K-12 Gene, 60, 1-11.
Becerril,B. Valle,F. Merino,E. Riba,L. Bolivar,F.
1985. Repetitive extragenic palindromic (REP) sequences in the Escherichia coli gdhA gene Gene, 37, 53-62.
Valle,F. Becerril,B. Chen,E. Seeburg,P. Heyneker,H. Bolivar,F.
1984. Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12 Gene, 27, 193-199.
Pozo-Yauner,L. Becerril,B. Ochoa-Leyva,A. Rodriguez-Ambriz,S.L. Perez-Carrion,J.I. Zavala-Padilla,G. Sanchez-Lopez,R. Fernandez-Velasco,D.A. 2015. The Structural Determinants of the Immunoglobulin Light Chain Amyloid Aggregation en: Jardon-Valadez,H.E. Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation. Cham. Springer International Publishing. pags. 1-28
Rodriguez-Rodriguez,E.R. Riano-Umbarila,L. Possani,L.D. Becerril,B. 2014. Recombinant neutralizing antibodies, a new generation of scorpion anti-venoms en: Gopalakrishnakone,P. Scorpion Venoms. Springer. pags. 139-159
del Pozo-Yauner,L. Ortiz,E. Becerril,B. 2009. Diseases related to protein misfolding en: Fernandez-Velasco,D.A. Advances in Protein Physical Chemistry. Kerala. Research Signpost. pags. 469-501
Gomez,I. Miranda-Rios,J. Arenas,I. Grande,R. Becerril,B. Bravo,A. Soberon,M. 2007. Identification of scFv Molecules that Recognize Loop 3 of Domain II and Domain III of Cry1Ab Toxin from Bacillus thuringiensis en: Vincent,C. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact,. Montreal. Erudit. pags. 12-14
Possani,L.D. Merino,E. Corona,M. Becerril,B. 2002. Scorpion genes and peptides specific for potassium channels: Structure, function and evolution en: Menez,A. Perspectives in Molecular Toxinology. pags. 201-214
Possani,L.D. Becerril,B. Tytgat,J. Delepierre,M. 2001. High Affinity Scorpion Toxins for Studying Potassium and Sodium Channels en: Nichols,C.G. Ion Channel Localization Methods and Protocols: Methods and Protocols. Humana Press. pags. 145-165
Otras Publicaciones Becerril,B. Villalba,M.I.
2015. Cuando las proteínas se agregan, te causan una enfermedad Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 3, 3-4.
Becerril-Lujan,B. Riano,L. Possani,L.
2014. Bancos de anticuerpos recombinantes de origen humano: una fuente ideal de antivenenos modernos contra la picadura de alacrán Revista Digital Universitaria, 15, art 84.
Becerril-Lujan,B. Riano-Umbarila,L.
2008. Quinta Generación de anti-venenos contra la picadura de alacrán Hypatia, 25, .
Chanez-Cardenas,M.E. Cisneros-Armas,D.A. Del Pozo-Yauner,L. Becerril,B. Fernandez-Velasco,D.A.
2002. Enfermedades relacionadas al plegamiento anómalo de las proteinas Mensaje Bioquimico, 26, 73-97.
Patentes Possani, L.D., Quintero, V., Gonzalez, L., Jiménez-Vargas, J.M., Ortiz, E., Corzo, G., Becerril, B., 2016 Composición farmacéutica de proteínas híbridas recombinantes capaces de generar anticuerpos neutralizantes en contra del veneno de alacranes.UNAM México. (en trámite)
L. Riaño U., B. Becerril L. y L. Possani P 2009 Variantes de anticuerpos humanos que reconocen específicamente a la toxina CN2 y al veneno del alacrán Centruroides noxius .UNAM México.
L. Riaño, B. Becerril y L.D. Possani 2008 Human antibody variants that specifically recognize the toxin CN2 from Centruroides noxius scorpion venom.UNAM Estados Unidos.
M. Corona, M. C. García, N. A. Valdez, G. Gurrola, B. Becerril y L.D. Possani 2008 Recombinant Immunogens for the Generation of Antivenoms to the Venom of Scorpions of the Genus Centruroides .UNAM Estados Unidos.
B. Becerril, F. Zamudio, B. Selisko, L.D. Possani, A. Ramírez y M. C. García 2005 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides (Divisional).UNAM México.
Riaño L. , B. Becerril y L.D. Possani 2005 Human antibody variants that specifically recognize the toxin CN2 from Centruroides noxius scorpionon venom.
M. Corona, M. C. García, N. A. Valdez, G. Gurrola, B. Becerril y L. D. Possani 2003 Inmunógenos recombinantes para la generación de antivenenos contra el veneno de alacranes del género Centruroides .UNAM México. (en trámite)
M. Corona, M. C. García, N. A. Valdez, G. Gurrola, B. Becerril y L. D. Possani 2002 Inmunógenos recombinantes para la generación de antivenenos contra el veneno de alacranes del género Centruroides .UNAM Estados Unidos. (en trámite)
B. Becerril, F. Zamudio, B. Selisko, L. D. Possani, A. Ramírez y C. García 2002 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides .UNAM México.
B. Becerril, F. Zamudio, B. Selisko, L.D. Possani, A. Ramírez y M.C. García 2002 Secuencia Primaria y ADNc de toxinas con actividad insecticida de alacranes del género Centruroides (Divisional).UNAM México.
B. Selisko, B. Becerril F. Zamudio, L. D. Possani A. Ramírez y C. García 2001 Primary sequence and cDNA of insecticidally effective toxins from scorpions of the genus Centruroides .UNAM Estados Unidos.
L. D. Possani, B. Becerril y A. F. Licea N 2001 ADNc y fragmento Fab del anticuerpo BCF2 y su utilización en composiciones farmacéuticas neutralizantes de veneno de alacrán.UNAM México.
L.D. Possani, B. Becerril, M. Corona, F. Ingerborg, F. Zamudio, E.S. Calderón, P. Litton y B.M. Martin 1995 Producao de peptideos de escorpioes Tityus serrulatus, Tityus bahiensis e Tityus stigmurus, e respectiva inmunizacao de cavalo, visando a obtencao de soros antiescorpionicos.UNAM-Fundación Butantan Brasil.
* Indica publicación con otra institución de adscripción
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