![]() | Dr. Juan Carlos Almagro Dominguez Teléfonos |
- Licenciatura: Bioquímica, Universidad de la Habana (1988)
- Doctorado: Doctorado. en Investigaciones Biomedicas, Instituto de Investigaciones Biomedicas, UNAM (1995)
- Mencion honorífica en estudios de Doctorado (1995)
- Medalla "Gabino Barreda"-UNAM, Doctorado (1997)
Almagro,J.C.
2004. Identification of differences in the specificity-determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody repertoires Journal of Molecular Recognition, 17, 132-143.
Rojas,G. Almagro,J.C. Acevedo,B. Gavilondo,J.V.
2002. Phage antibody fragments library combining a single human light chain variable region with immune mouse heavy chain variable regions Journal of Biotechnology, 94, 287-298.
Ramirez-Benitez,M.C. Moreno-Hagelsieb,G. Almagro,J.C.
2001. VIR.II: a new interface with the antibody sequences in the Kabat database Biosystems, 61, 125-131.
Ramirez-Benitez,M.D. Almagro,J.C.
2001. Analysis of antibodies of known structure suggests a lack of correspondence between the residues in contact with the antigen and those modified by somatic hypermutation Proteins, 45, 199-206.
Manoutcharian,K. Gevorkian,G. Cano,A. Almagro,J.C.
2001. Phage displayed biomolecules as preventive and therapeutic agents Current Pharmaceutical Biotechnology, 2, 217-223.
Almagro,J.C. Hernandez,I. Ramirez,M.C. Vargas-Madrazo,E.
1998. Structural differences between the repertoires of mouse and human germline genes and their evolutionary implications Immunogenetics, 47, 355-363.
Gevorkian,G. Manoutcharian,K. Almagro,J.C. Govezensky,T. Dominguez,V.
1998. Identification of autoimmune thrombocytopenic purpura-related epitopes using phage-display peptide library Clinical Immunology and Immunopathology, 86, 305-309.
Vorobjev,Y.N. Almagro,J.C. Hermans,J.
1998. 3.0.CO;2-C> Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model Proteins, 32, 399-413 * .
Vargas-Madrazo,E. Lara-Ochoa,F. Ramirez-Benites,M.C. Almagro,J.C.
1997. Evolution of the structural repertoire of the human V(H) and Vkappa germline genes International Immunopharmacology, 9, 1801-1815 * .
Almagro,J.C. Hernandez,I. Ramirez,M.D. Vargas-Madrazo,E.
1997. The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response Molecular Immunology, 34, 1199-1214.
Almagro,J.C. Dominguez-Martinez,V. Lara-Ochoa,F. Vargas-Madrazo,E.
1996. Structural repertoire in human VL pseudogenes of immunoglobulins: comparison with functional germline genes and amino acid sequences Immunogenetics, 43, 92-96 * .
Lara-Ochoa,F. Almagro,J.C. Vargas-Madrazo,E. Mendez,I.
1996. Frequency analysis of amino acids in the recognition regions of T-cell receptors Biosystems, 39, 77-85 * .
Gevorkian,G. Manoutcharian,K. Larralde,C. Hernandez,M. Almagro,J.C. Viveros,M. Sorelo,J. Garcia,E. Sciutto,E.
1996. Immunodominant synthetic peptides of Taenia crassiceps in murine and human cysticercosis Immunology Letters, 49, 185-189 * .
Lara-Ochoa,F. Almagro,J.C. Vargas-Madrazo,E. Conrad,M.
1996. Antibody-antigen recognition: a canonical structure paradigm Journal of Molecular Evolution, 43, 678-684 * .
Almagro,J.C. Vargas-Madrazo,E. Zenteno-Cuevas,R. Hernandez-Mendiola,V. Lara-Ochoa,F.
1995. VIR: a computational tool for analysis of immunoglobulin sequences Biosystems, 35, 25-32 * .
Almagro,J.C. Zenteno,R. Vargas-Madrazo,E. Lara-Ochoa,F.
1995. Variability analysis of the T-cell receptors using three variability indexes International Journal of Peptide and Protein Research, 45, 180-186 * .
Vargas-Madrazo,E. Almagro,J.C. Lara-Ochoa,F.
1995. Structural repertoire in VH pseudogenes of immunoglobulins: comparison with human germline genes and human amino acid sequences Journal of Molecular Biology, 246, 74-81 * .
Lara-Ochoa,F. Vargas-Madrazo,E. Almagro,J.C.
1995. Distributions of the use frequencies of amino acids in the hypervariable regions of immunoglobulins Journal of Molecular Evolution, 41, 98-103 * .
Almagro,J.C. Vargas-Madrazo,E. Lara-Ochoa,F. Horjales,E.
1995. Molecular modeling of a T-cell receptor bound to a major histocompatibility complex molecule: implications for T-cell recognition Protein Science, 4, 1708-1717 * .
Vargas-Madrazo,E. Lara-Ochoa,F. Almagro,J.C.
1995. Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition Journal of Molecular Biology, 254, 497-504 Correction 258 (5) 893 * .
Lara-Ochoa,F. Vargas-Madrazo,E. Jimenez-Montano,M.A. Almagro,J.C.
1994. Patterns in the complementary determining regions of immunoglobulins (CDRs) Biosystems, 32, 1-9 * .
* Indica publicación con otra institución de adscripción