IBT-UNAM : Dr. Alfredo Martínez Jimenez
Dr. Alfredo Martínez Jimenez Grupo
Departamento de Ingeniería Celular y Biocatálisis
Líneas de investigación
-Página personal-
email: alfredo @ibt.unam.mx
Teléfonos
Oficina +52 (777) 329-1777 ext 38120. red UNAM 38120 Laboratorio +52 (777) 329-1601 red UNAM 27601
- Licenciatura: Ingeniería Bioquímica Industrial, Universidad Autonoma Metropolitana (1981-1985)
Reconocimiento SCOPUS-ELSEVIER-MÉXICO 2012 en Biotecnología y Ciencias Agropecuarias Editorial Scopus-Elsevier (2012)
Estudiantes Leonardo Peña
Ing. Fidel Oswaldo Ramirez "Ingeniería metabólica de Escherichia coli para la producción de (R)-3-hidroxibutirato utilizando glicerol como fuente de carbono."
IBQ. María de los Angeles Martinez
Biol. Karla Vianey Martínez
M.C. Karina Jasmin Salcedo
M.C. Francisco Vera
Ing. Luz Teresa Reyes
Karen Patricia Vega
Ing. Erick Ortiz
Ing. Wanda Yael Tlalmis
M.C. Carlos Alberto Montenegro
Publicaciones recientes
Werlang,E.B. Sierra-Ibarra,E. Neves,F.F. Julich,J. Martinez,A. Schneider,R.C.S.
2020. d-lactate production from Spirulina (Arthrospira platensis) biomass using lactogenic Escherichia coli Bioresource Technology Reports, 12, 100598.
Sierra-Ibarra,E. Leal-Reyes,L.J. Huerta-Beristain,G. Hernandez-Orihuela,A.L. Gosset,G. Martinez-Antonio,A. Martinez,A.
2020. Limited oxygen conditions as an approach to scale-up and improve D and L-lactic acid production in mineral media and avocado seed hydrolysates with metabolically engineered Escherichia coli Bioprocess and Biosystems Engineering, Oct 7 [Epub ahead of print], .
Werlang,E.B. Julich,J. Muller,M.V.G. de Farias Neves,F. Sierra-Ibarra,E. Martinez,A. Schneider,R.C.S.
2020. Bioethanol from hydrolyzed Spirulina (Arthrospira platensis) biomass using ethanologenic bacteria Bioresources and Bioprocessing, 7, 27.
Martinez,L.M. Martinez,A. Gosset,G.
2019. Production of Melanins With Recombinant Microorganisms Frontiers in Bioengineering and Biotechnology, 7, 285.
Fernandez-Sandoval,M.T. Galindez-Mayer,J. Bolivar,F. Gosset,G. Ramirez,O.T. Martinez,A.
2019. Xylose-glucose co-fermentation to ethanol by Escherichia coli strain MS04 using single- and two-stage continuous cultures under micro-aerated conditions Microbial Cell Factories, 18, 145.
Sigala,J.C. Quiroz,L. Arteaga,E. Olivares,R. Lara,A.R. Martinez,A.
2019. Physiological and transcriptional comparison of acetate catabolism between Acinetobacter schindleri ACE and Escherichia coli JM101 Fems Microbiology Letters, 366, fnz151.
Caspeta,L. Coronel,J. de Oca,A.M. Abarca,E. Gonzalez,L. Martinez,A.
2019. Engineering high-gravity fermentations for ethanol production at elevated-temperature with Saccharomyces cerevisiae Biotechnology and Bioengineering, 116, 2587-2597.
Salcedo-Vite,K. Sigala,J.C. Segura,D. Gosset,G. Martinez,A.
2019. Acinetobacter baylyi ADP1 growth performance and lipid accumulation on different carbon sources Applied Microbiology and Biotechnology, 103, 6217-6229.
Carreon-Rodriguez,O.E. Gutierrez-Rios,R.M. Acosta,J.L. Martinez,A. Cevallos,M.A.
2019. Phenotypic and genomic analysis of Zymomonas mobilis ZM4 mutants with enhanced ethanol tolerance Biotechnology Reports, 23, e00328.
Fragoso-Jimenez,J.C. Baert,J. Nguyen,T.M. Liu,W. Sassi,H. Goormaghtigh,F. Van Melderen L. Gaytan,P. Hernandez-Chavez,G. Martinez,A. Delvigne,F. Gosset,G.
2019. Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity Microbial Cell Factories, 18, 26.
Hernandez-Chavez,G. Martinez,A. Gosset,G.
2019. Metabolic engineering strategies for caffeic acid production in Escherichia coli Electronic Journal of Biotechnology, 38, 19-26.
Arana-Cuenca,A. Tovar-Ximenez,X. Favela-Torres,E. Perraud-Gaime,I. Gonzalez-Becerra,A.E. Martinez,A. Moss-Acosta,C.L. Mercado-Flores,Y. Tellez-Jurado,A.
2019. Use of water hyacinth as a substrate for the production of filamentous fungal hydrolytic enzymes in solid-state fermentation 3 Biotech, 9, 21.
Parra-Ramirez,D. Martinez,A. Cardona,C.A.
2019. Lactic acid production from glucose and xylose using the lactogenic Escherichia coli strain JU15: Experiments and techno-economic results Bioresource Technology, 273, 86-92.
Parra-Ramirez,D. Martinez,A. Cardona,C.A.
2018. Technical and economic potential evaluation of the strain Escherichia coli MS04 in the ethanol production from glucose and xylose Biochemical Engineering Journal, 140, 123-129.
Perez-Cadena,R. Medina-Moreno,S.A. Martinez,A. Lizardi-Jimenez,M.A. Espinosa-Solares,T. Tellez-Jurado,A.
2018. Effect of concentration of salts in ethanol production from acid hydrolysis of cladodes of opuntia ficus indica var. Atlixco [Efecto de la concentración de sales en la producción de etanol a partir de la hidrólsis ácida de cladodios de opuntia ficus indica var. Atlixco] Revista Mexicana de Ingenieria Quimica, 17, 349-364.
Serna-Loaiza,S. Martinez,A. Pisarenko,Y. Cardona-Alzate,C.A.
2018. Integral use of plants and their residues: the case of cocoyam (Xanthosoma sagittifolium) conversion through biorefineries at small scale Environmental Science and Pollution Research, 25, 35949-35959.
Salas-Navarrete,C. Hernandez-Chavez,G. Flores,N. Martinez,L.M. Martinez,A. Bolivar,F. Barona-Gomez,F. Gosset,G.
2018. Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl carrier protein reductase Electronic Journal of Biotechnology, 33, 11-16.
Rios,L.F. Martinez,A. Klein,B.C. Maciel,M.R. Filho,R.
2018. Comparison of Growth and Lipid Accumulation at Three Different Growth Regimes with Desmodesmus sp Waste and Biomass Valorization, 9, 421-427.
Sigala,J.C. Suarez,B.P. Lara,A.R. Borgne,S.L. Bustos,P. Santamaria,R.I. Gonzalez,V. Martinez,A.
2017. Genomic and physiological characterization of a laboratory-isolated Acinetobacter schindleri ACE strain that quickly and efficiently catabolizes acetate Microbiology, 163, 1052-1064.
Martinez,A. Rito-Palomares,M. Castro-Montoya,A.J.
2017. In Focus: Biotechnology and chemical technology for biorefineries and biofuel production Journal of Chemical Technology & Biotechnology, 92, 897-898.
Rios-Gonzalez,L.J. Morales-Martinez,T.K. Rodriguez-Flores,M.F. Rodriguez-De la Garza JA Castillo-Quiroz,D. Castro-Montoya,A.J. Martinez,A.
2017. Autohydrolysis pretreatment assessment in ethanol production from agave bagasse Bioresource Technology, 242, 184-190.
Rios-Franquez,F.J. Gonzalez-Bautista,E. Ponce-Noyola,T. Ramos-Valdivia,A.C. Poggi-Varaldo,H.M. Garcia-Mena,J. Martinez,A.
2017. Expression of a codon-optimized beta-glucosidase from Cellulomonas flavigena PR-22 in Saccharomyces cerevisiae for bioethanol production from cellobiose Archives of Microbiology, 199, 605-611.
Huerta-Beristain,G. Cabrera-Ruiz,R. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2017. Metabolic engineering and adaptive evolution of Escherichia coli KO11 for ethanol production through the Entner-Doudoroff and the pentose phosphate pathways Journal of Chemical Technology and Biotechnology, 92, 990-996.
Perez-Pimienta,J.A. Vargas-Tah,A. Lopez-Ortega,K.M. Medina-Lopez,Y.N. Mendoza-Perez,J.A. Avila,S. Singh,S. Simmons,B.A. Loaces,I. Martinez,A.
2017. Sequential enzymatic saccharification and fermentation of ionic liquid and organosolv pretreated agave bagasse for ethanol production Bioresource Technology, 225, 191-198.
Garibay-Hernandez,A. Barkla,B.J. Vera-Estrella,R. Martinez,A. Pantoja,O.
2017. Membrane proteomic insights into the physiology and taxonomy of an oleaginous green microalga Plant Physiology, 173, 390-416.
Morales-Sanchez,D. Martinez-Rodriguez,O.A. Martinez,A.
2017. Heterotrophic cultivation of microalgae: production of metabolites of commercial interest Journal of Chemical Technology & Biotechnology, 92, 925-936.
Fernandez-Sandoval,M.T. Galindez-Mayer,J. Moss-Acosta,C.L. Gosset,G. Martinez,A.
2017. Volumetric oxygen transfer coefficient as a means of improving volumetric ethanol productivity and a criterion for scaling up ethanol production with Escherichia coli Journal of Chemical Technology & Biotechnology, 92, 981-989.
Ruiz,H.A. Martinez,A. Vermerris,W.
2016. Bioenergy Potential, Energy Crops, and Biofuel Production in Mexico Bioenergy Research, 9, 981-984.
Morales-Sanchez,D. Kyndt,J. Ogden,K. Martinez,A.
2016. Toward an understanding of lipid and starch accumulation in microalgae: A proteomic study of Neochloris oleoabundans cultivated under N-limited heterotrophic conditions Algal Research, 20, 22-34.
Camacho-Zaragoza,J.M. Hernandez-Chavez,G. Moreno-Avitia,F. Ramirez-Iniguez,R. Martinez,A. Bolivar,F. Gosset,G.
2016. Engineering of a microbial coculture of Escherichia coli strains for the biosynthesis of resveratrol Microbial Cell Factories, 15, 163.
Mejia-Caballero,A. de Anda,R. Hernandez-Chavez,G. Rogg,S. Martinez,A. Bolivar,F. Castano,V.M. Gosset,G.
2016. Biosynthesis of catechol melanin from glycerol employing metabolically engineered Escherichia coli Microbial Cell Factories, 15, 161.
Orencio-Trejo,M. Torres-Granados,J. Rangel-Lara,A. Beltran-Guerrero,E. Garcia-Aguilar,S. Moss-Acosta,C. Valenzuela-Soto,H. de la Torre-Zavala,S. Gastelum-Arellanez,A. Martinez,A. Tiessen,A. Diaz-Mireles,E. Lozoya-Gloria,E.
2016. Cellulase and Xylanase Production by the Mexican Strain Talaromyces stollii LV186 and Its Application in the Saccharification of Pretreated Corn and Sorghum Stover Bioenergy Research, 9, 1034-1045.
Utrilla,J. Vargas-Tah,A. Trujillo-Martinez,B. Gosset,G. Martinez,A.
2016. Production of d-lactate from sugarcane bagasse and corn stover hydrolysates using metabolic engineered Escherichia coli strains Bioresource Technology, 220, 208-214.
Pedraza,L. Flores,A. Toribio,H. Quintero,R. Le Borgne,S. Moss-Acosta,C. Martinez,A.
2016. Sequential Thermochemical Hydrolysis of Corncobs and Enzymatic Saccharification of the Whole Slurry Followed by Fermentation of Solubilized Sugars to Ethanol with the Ethanologenic Strain Escherichia coli MS04 Bioenergy Research, 9, 1046-1052.
Rojas-Rejon,O.A. Poggi-Varaldo,H.M. Cristiani-Urbina,E. Martinez,A. Ramos-Valdivia,A.C. de laTorre M. Ponce-Noyola,T.
2016. Enzymatic saccharification of sugar cane bagasse by continuous xylanase and cellulase production from Cellulomonas flavigena PR-22 Biotechnology Progress, 32, 321-326.
Loaces,I. Bottini,G. Moyna,G. Fabiano,E. Martinez,A. Noya,F.
2016. EndoG: a novel multifunctional halotolerant glucanase and xylanase isolated from cow rumen Journal of Molecular Catalysis B: Enzymatic, 126, 1-9.
Vargas-Tah,A. Moss-Acosta,C.L. Trujillo-Martinez,B. Tiessen,A. Lozoya-Gloria,E. Orencio-Trejo,M. Gosset,G. Martinez,A.
2015. Non-severe thermochemical hydrolysis of stover from white corn and sequential enzymatic saccharification and fermentation to ethanol Bioresource Technology, 198, 611-618.
Loaces,I. Amarelle,V. Munoz-Gutierrez,I. Fabiano,E. Martinez,A. Noya,F.
2015. Improved ethanol production from biomass by a rumen metagenomic DNA fragment expressed in Escherichia coli MS04 during fermentation Applied Microbiology and Biotechnology, 99, 9049-9060.
Vargas-Tah,A. Martinez,L. Hernandez-Chavez,G. Rocha,M. Martinez,A. Bolivar,F. Gosset,G.
2015. Production of cinnamic and p -hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli Microbial Cell Factories, 14, 6.
Morales-Sanchez,D. Martinez-Rodriguez,O.A. Kyndt,J. Martinez,A.
2015. Heterotrophic growth of microalgae: metabolic aspects World Journal Of Microbiology & Biotechnology, 31, 1-9.
Balderas-Hernandez,V.E. Trevino-Quintanilla,L.G. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2014. Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1 Microbial Cell Factories, 13, 136.
Munoz-Gutierrez,I. Moss-Acosta,C. Trujillo-Martinez,B. Gosset,G. Martinez,A.
2014. Ag43-mediated display of a thermostable ß-glucosidase in Escherichia coli and its use for simultaneous saccharification and fermentation at high temperatures. Microbial Cell Factories, 13, 106.
Morales-Sanchez,D. Tinoco-Valencia,R. Caro-Bermudez,M.A. Martinez,A.
2014. Culturing Neochloris oleoabundans microalga in a nitrogen-limited, heterotrophic fed-batch system to enhance lipid and carbohydrate accumulation Algal Research, 5, 61-69.
Centeno-Leija,S. Huerta-Beristain,G. Giles-Gomez,M. Bolivar,F. Gosset,G. Martinez,A.
2014. Improving poly-3-hydroxybutyrate production in Escherichia coli by combining the increase in the NADPH pool and acetyl-CoA availability Antonie Van Leeuwenhoek, 105, 687-696.
Licona-Cassani,C. Lara,A.R. Cabrera-Valladares,N. Escalante,A. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2014. Inactivation of Pyruvate Kinase or the Phosphoenolpyruvate: Sugar Phosphotransferase System Increases Shikimic and Dehydroshikimic Acid Yields from Glucose in Bacillus subtilis Journal of Molecular Microbiology and Biotechnology, 24, 37-45.
Caspeta,L. Caro-Bermudez,M.A. Ponce-Noyola,T. Martinez,A.
2014. Enzymatic hydrolysis at high-solids loadings for the conversion of agave bagasse to fuel ethanol Applied Energy, 113, 277-286.
Chavez-Bejar,M.I. Balderas-Hernandez,V.E. Gutierrez-Alejandre,A. Martinez,A. Bolivar,F. Gosset,G.
2013. Metabolic engineering of Escherichia coli to optimize melanin synthesis from glucose Microbial Cell Factories, 12, 108.
Garibay-Hernandez,A. Vazquez-Duhalt,R. Serrano-Carreon,L. Martinez,A.
2013. Nitrogen Limitation in Neochloris oleoabundans: A Reassessment of Its Effect on Cell Growth and Biochemical Composition Applied Biochemistry and Biotechnology, 171, 1775-1791.
Centeno-Leija,S. Utrilla,J. Flores,N. Rodriguez,A. Gosset,G. Martinez,A.
2013. Metabolic and transcriptional response of Escherichia coli with a NADP-dependent glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans Antonie Van Leeuwenhoek, 104, 913-924.
Morales-Sanchez,D. Tinoco-Valencia,R. Kyndt,J. Martinez,A.
2013. Heterotrophic growth of Neochloris oleoabundans using glucose as a carbon source Biotechnology for Biofuels, 6, 100.
Fuentes,L.G. Lara,A.R. Martinez,L.M. Ramirez,O.T. Martinez,A. Bolivar,F. Gosset,G.
2013. Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production Microbial Cell Factories, 12, 42.
Munoz-Gutierrez,I. Martinez,A.
2013. Polysaccharide hydrolysis with engineered Escherichia coli for the production of biocommodities Journal of Industrial Microbiology & Biotechnology, 40, 401-410.
Sabido,A. Martinez,L.M. de Anda,R. Martinez,A. Bolivar,F. Gosset,G.
2013. A novel plasmid vector designed for chromosomal gene integration and expression: Use for developing a genetically stable Escherichia coli melanin production strain Plasmid, 69, 16-23.
Utrilla,J. Licona-Cassani,C. Marcellin,E. Gosset,G. Nielsen,L.K. Martinez,A.
2012. Engineering and adaptive evolution of Escherichia coli for d-lactate fermentation reveals GatC as a xylose transporter Metabolic Engineering, 14, 469-476.
Cabrera-Valladares,N. Martinez,L.M. Flores,N. Hernandez-Chavez,G. Martinez,A. Bolivar,F. Gosset,G.
2012. Physiologic Consequences of Glucose Transport and Phosphoenolpyruvate Node Modifications in Bacillus subtilis 168 Journal of Molecular Microbiology and Biotechnology, 22, 177-197.
Fernandez-Sandoval,M.T. Huerta-Beristain,G. Trujillo-Martinez,B. Bustos,P. Gonzalez,V. Bolivar,F. Gosset,G. Martinez,A.
2012. Laboratory metabolic evolution improves acetate tolerance and growth on acetate of ethanologenic Escherichia coli under non-aerated conditions in glucose-mineral medium Applied Microbiology and Biotechnology, 96, 1291-1300.
Munoz-Gutierrez,I. Oropeza,R. Gosset,G. Martinez,A.
2012. Cell surface display of a beta-glucosidase employing the type V secretion system on ethanologenic Escherichia coli for the fermentation of cellobiose to ethanol Journal of Industrial Microbiology & Biotechnology, 39, 1141-1152.
Chavez-Bejar,M.I. Baez-Viveros,J.L. Martinez,A. Bolivar,F. Gosset,G.
2012. Biotechnological production of l-tyrosine and derived compounds Process Biochemistry, 47, 1017-1026.
Munoz,A.J. Hernandez-Chavez,G. de Anda,R. Martinez,A. Bolivar,F. Gosset,G.
2011. Metabolic engineering of Escherichia coli for improving L: -3,4-dihydroxyphenylalanine (L: -DOPA) synthesis from glucose Journal of Industrial Microbiology & Biotechnology, 38, 1845-1852.
Rojas-Rejon,O.A. Poggi-Varaldo,H.M. Ramos-Valdivia,A.C. Martinez-Jimenez,A. Cristiani-Urbina,E. De La Torre Martinez,M. Ponce-Noyola,T.
2011. Production of cellulases and xylanases under catabolic repression conditions from mutant PR-22 of Cellulomonas flavigena Journal of Industrial Microbiology & Biotechnology, 38, 257-264.
Balderas-Hernandez,V.E. Hernandez-Montalvo,V. Bolivar,F. Gosset,G. Martinez,A.
2011. Adaptive Evolution of Escherichia coli Inactivated in the Phosphotransferase System Operon Improves Co-utilization of Xylose and Glucose Under Anaerobic Conditions Applied Biochemistry and Biotechnology, 163, 485-496.
Quiroz-Castaneda,R.E. Balcazar-Lopez,E. Dantan-Gonzalez,E. Martinez,A. Folch-Mallol,J. Martínez-Anaya,C.
2009. Characterization of cellulolytic activities of Bjerkandera adusta and Pycnoporus sanguineus on solid wheat straw medium Electronic Journal of Biotechnology, 12, Oct 15.
Utrilla,J. Gosset,G. Martinez,A.
2009. ATP limitation in a pyruvate formate lyase mutant of Escherichia coli MG1655 increases glycolytic flux to D: -lactate Journal of Industrial Microbiology & Biotechnology, 36, 1057-1062.
Romero-Garcia,S. Hernandez-Bustos,C. Merino,E. Gosset,G. Martinez,A.
2009. Homolactic fermentation from glucose and cellobiose using Bacillus subtilis Microbial Cell Factories, 8, 23.
Balderas-Hernandez,V.E. Sabido-Ramos,A. Silva,P. Cabrera-Valladares,N. Hernandez-Chavez,G. Baez-Viveros,J.L. Martinez,A. Bolivar,F. Gosset,G.
2009. Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli Microbial Cell Factories, 8, 19.
Orencio-Trejo,M. Flores,N. Escalante,A. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2008. Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities Biotechnology for Biofuels, 1, 8.
Huerta-Beristain,G. Utrilla,J. Hernandez-Chavez,G. Bolivar,F. Gosset,G. Martinez,A.
2008. Specific ethanol production rate in ethanologenic Escherichia coli strain KO11 Is limited by pyruvate decarboxylase Journal of Molecular Microbiology and Biotechnology, 15, 55-64.
Chavez-Bejar,M.I. Lara,A.R. Lopez,H. Hernandez-Chavez,G. Martinez,A. Ramirez,O.T. Bolivar,F. Gosset,G.
2008. Metabolic engineering of Escherichia coli for L-tyrosine production by the expression of the genes coding for the chorismate mutase domain from native P-protein and a cyclohexadienyl dehydrogenase from Zymomonas mobilis Applied and Environmental Microbiology, 74, 3284-3290.
Martinez,A.
2007. Engineering Bacillus subtilis to produce ethanol.Industrial Bioprocessing, 29, 8.
Vazquez-Limon,C. Vega-Badillo,J. Martinez,A. Espinosa-Molina,G. Gosset,G. Soberon,X. Lopez-Munguia,A. Osuna,J.
2007. Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD(+) regeneration Biotechnology Letters, 29, 1857-1863.
Pinero,S. Rivera,J. Romero,D. Cevallos,M.A. Martinez,A. Bolivar,F. Gosset,G.
2007. Tyrosinase from Rhizobium etli Is Involved in Nodulation Efficiency and Symbiosis-Associated Stress Resistance Journal of Molecular Microbiology and Biotechnology, 13, 35-44.
Flores,N. Leal,L. Sigala,J.C. de Anda,R. Escalante,A. Martinez,A. Ramirez,O.T. Gosset,G. Bolivar,F.
2007. Growth Recovery on Glucose under Aerobic Conditions of an Escherichia coli Strain Carrying a Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Deletion by Inactivating arcA and Overexpressing the Genes Coding for Glucokinase and Galactose Permease Journal of Molecular Microbiology and Biotechnology, 13, 105-116.
Trevino-Quintanilla,L.G. Escalante,A. Caro,A.D. Martinez,A. (error para richar) Puente,J.L. Bolivar,F. Gosset,G.
2007. The Phosphotransferase System-Dependent Sucrose Utilization Regulon in Enteropathogenic Escherichia coli Strains Is Located in a Variable Chromosomal Region Containing iap Sequences Journal of Molecular Microbiology and Biotechnology, 13, 117-125.
Romero,S. Merino,E. Bolivar,F. Gosset,G. Martinez,A.
2007. Metabolic engineering of Bacillus subtilis for ethanol production: Lactate dehydrogenase plays a key role in the fermentative metabolism Applied and Environmental Microbiology, 73, 5190-5198.
Martinez,A. Grabar,T.B. Shanmugam,K.T. Yomano,L.P. York,S.W. Ingram,L.O.
2007. Low salt medium for lactate and ethanol production by recombinant Escherichia coli B Biotechnology Letters, 29, 397-404.
Lagunas-Munoz,V.H. Cabrera-Valladares,N. Bolivar,F. Gosset,G. Martinez,A.
2006. Optimum melanin production using recombinant Escherichia coli Journal of Applied Microbiology, 101, 1002-1008.
Cabrera-Valladares,N. Martinez,A. Pinero,S. Lagunas-Munoz,V.H. Tinoco,R. de Anda,R. Vazquez-Duhalt,R. Bolivar,F. Gosset,G.
2006. Expression of the melA gene from Rhizobium etli CFN42 in Escherichia coli and characterization of the encoded tyrosinase Enzyme and Microbial Technology, 38, 772-779.
Flores,N. de Anda,R. Flores,S. Escalante,A. Hernandez,G. Martinez,A. Ramirez,O.T. Gosset,G. Bolivar,F.
2004. Role of Pyruvate Oxidase in Escherichia coli Strains Lacking the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Journal of Molecular Microbiology and Biotechnology, 8, 209-221.
Escalante,A. Rodriguez,M.E. Martinez,A. Lopez-Munguia,A. Bolivar,F. Gosset,G.
2004. Characterization of bacterial diversity in Pulque, a traditional Mexican alcoholic fermented beverage, as determined by 16S rDNA analysis Fems Microbiology Letters, 235, 273-279.
Garay-Arroyo,A. Covarrubias,A.A. Clark,I. Nino,I. Gosset,G. Martinez,A.
2004. Response to different environmental stress conditions of industrial and laboratory Saccharomyces cerevisiae strains Applied Microbiology and Biotechnology, 63, 734-741.
Hernandez-Montalvo,V. Martinez,A. Bolivar,F. Valle,F. Gosset,G.
2003. Expression of galP and glk in a Escherichia coli PTS mutant restores glucose transport and increases glycolytic flux to fermentation products Biotechnology and Bioengineering, 83, 687-694.
Tao,H. Gonzalez,R. Martinez,A. Rodriguez,M. Ingram,L.O. Preston,J.F. Shanmugam,K.T.
2001. Engineering a homo-ethanol pathway in Escherichia coli: increased glycolytic flux and levels of expression of glycolytic genes during xylose fermentation Journal of Bacteriology, 183, 2979-2988 * .
Espinosa-de-los Monteros,J. Martinez,A. Valle,F.
2001. Metabolic profiles and aprE expression in anaerobic cultures of Bacillus subtilis using nitrate as terminal electron acceptor Applied Microbiology and Biotechnology, 57, 379-384.
Martinez,A. Rodriguez,M.E. Wells,M.L. York,S.W. Preston,J.F. Ingram,L.O.
2001. Detoxification of dilute acid hydrolysates of lignocellulose with lime Biotechnology Progress, 17, 287-293.
Zaldivar,J. Martinez,A. Ingram,L.O.
2000. 3.0.CO;2-T> Effect of alcohol compounds found in hemicellulose hydrolysate on the growth and fermentation of ethanologenic Escherichia coli Biotechnology and Bioengineering, 68, 524-530.
Martinez,A. Rodriguez,M.E. York,S.W. Preston,J.F. Ingram,L.O.
2000. 3.0.CO;2-E> Effects of Ca(OH)(2) treatments ("overliming") on the composition and toxicity of bagasse hemicellulose hydrolysates Biotechnology and Bioengineering, 69, 526-536.
Martinez,A. Rodriguez,M.E. York,S.W. Preston,J.F. Ingram,L.O.
2000. Use of UV absorbance To monitor furans in dilute acid hydrolysates of biomass Biotechnology Progress, 16, 637-641.
Martinez-Morales,F. Borges,A.C. Martinez,A. Shanmugam,K.T. Ingram,L.O.
1999. Chromosomal integration of heterologous DNA in Escherichia coli with precise removal of markers and replicons used during construction Journal of Bacteriology, 181, 7143-7148.
Zaldivar,J. Martinez,A. Ingram,L.O.
1999. 3.0.CO;2-2> Effect of selected aldehydes on the growth and fermentation of ethanologenic Escherichia coli Biotechnology and Bioengineering, 65, 24-33.
Ingram,L.O. Aldrich,H.C. Borges,A.C. Causey,T.B. Martinez,A. Morales,F. Saleh,A. Underwood,S.A. Yomano,L.P. York,S.W. Zaldivar,J. Zhou,S.
1999. Enteric bacterial catalysts for fuel ethanol production Biotechnology Progress, 15, 855-866.
Martinez,A. York,S.W. Yomano,L.P. Pineda,V.L. Davis,F.C. Shelton,J.C. Ingram,L.O.
1999. Biosynthetic burden and plasmid burden limit expression of chromosomally integrated heterologous genes (pdc, adhB) in Escherichia coli Biotechnology Progress, 15, 891-897.
Siguenza,R. Flores,N. Hernandez,G. Martinez,A. Bolivar,F. Valle,F.
1999. Kinetic characterization in batch and continuous culture of Escherichia coli mutants affected in phosphoenolpyruvate metabolism: differences in acetic acid production World Journal Of Microbiology & Biotechnology, 15, 587-592.
Ponce,E. Martinez,A. Bolivar,F. Valle,F.
1998. 3.0.CO;2-D> Stimulation of glucose catabolism through the pentose pathway by the absence of the two pyruvate kinase isoenzymes in Escherichia coli Biotechnology and Bioengineering, 58, 292-295.
Martinez,A. Ramirez,O.T. Valle,F.
1998. Effect of growth rate on the production of beta-galactosidase from Escherichia coli in Bacillus subtilis using glucose- limited exponentially fedbatch cultures Enzyme and Microbial Technology, 22, 520-526.
Martinez,A. Ramirez,O.T. Valle,F.
1997. Improvement of culture conditions to overproduce beta-galactosidase from Escherichia coli in Bacillus subtilis Applied Microbiology and Biotechnology, 47, 40-45.
Galindo,E. Arguello,M. Velasco,D.A. Albiter,V. Martinez,A.
1996. A comparison of cavern development in mixing a yield stress fluid by Rushton and Intermig impellers Chemical Engineering & Technology, 19, 315-323.
Ponce,E. Flores,N. Martinez,A. Valle,F. Bolivar,F.
1995. Cloning of the two pyruvate kinase isoenzyme structural genes from Escherichia coli: the relative roles of these enzymes in pyruvate biosynthesis Journal of Bacteriology, 177, 5719-5722.
Gosset,G. de Anda,R. Cruz,N. Martinez,A. Quintero,R. Bolivar,F.
1993. Recombinant protein production in cultures of an Escherichia coli trp- strain Applied Microbiology and Biotechnology, 39, 541-546.
Bravo,A. Quintero,R. Diaz,C. Martinez,A. Soberon,M.
1993. Efficiency of insecticidal crystal protein production in a Bacillus thuringiensis mutant with derepressed expression of the terminal oxidase aa3 during sporulation Applied Microbiology and Biotechnology, 39, 558-562.
Sanchez,A. Martinez,A. Torres,L. Galindo,E.
1992. Power consumption of three impeller combinations in mixing Xanthan fermentation broths Process Biochemistry, 27, 351-365.
Resendiz,R. Martinez,A. Ascanio,G. Galindo,E.
1991. New pneumatic bearing dynamometer for power input measurement in stirred tanks Chemical Engineering & Technology, 14, 105-108.
Martinez,A. Galindo,E. Salvador,M.
1989. Sparger position effect over kLa in bench and pilot stirred-tank fermentors Journal Of Fermentation And Bioengineering, 68, 71-73.
Libros y capítulos recientes Perez-Cadena,R. Sanchez-Contreras,M.A. Espinosa-Solares,T. Medina-Moreno,S.A. Lizardi-Jimenez,A. Martinez-Jimenez,A. Castro-Rosas,J. Tellez-Jurado,A. 2017. Opuntia spp.como sustato para la producción de bioetanol en: Téllez-Jurado,A. Biotecnología y Alimentos en Hidalgo: Transitando a la Bioeconomía. Ciudad de Mexico. Amalgama Arte Editorial S.A. de C.C.,. pags. 156-169
Parra-Ramirez,D. Martinez,A. Aroca,G. Quintero,J.A. Cardona-Alzate,C. 2017. Biobutanol as a Platform for Future Biorefineries en: Torres,I. Biorefineries: Concepts, Advancements and Research. Hauppauge, New York. Nova Science Publishers. pags. 73-108
Martinez,A. Rodriguez-Alegria,M. Fernandes,M.C. Gosset,G. Vargas-Tah,A. 2017. Metabolic Engineering of Escherichia coli for Lactic Acid Production from Renewable Resources en: *gosset Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. Cham. Springer International Publishing. pags. 125-145
Morales-Sanchez,D. Trejo-Hernandez,A. Vazquez-Duhalt,R. Martinez-Jimenez,A. 2012. Produccion de biodiesel a partir de microalgas en: Esqueda-Valle,M. Uso de la biodiversidad para bioenergía y biocombustibles en zonas áridas de México. CIAD-UNISON. pags. 114-155
Martinez-Jimenez,A. 2011. Ingeniería Metabólica para la obtención de etanol carburante a partir de hidrolizados de bagazo de caña en: Romero,J.A. El impacto de los Fondos Mixtos en el Desarrollo Regional Vol. II.. Mexico,D.F.. Foro Consultivo Científico y Tecnológico, A.C. pags. 13-23
Orencio-Trejo,M. Utrilla,J. Fernandez-Sandoval,M.T. Huerta-Beristain,G. Gosset,G. Martinez,A. 2010. Engineering the Escherichia coli Fermentative Metabolism en: Krull,R. Biosystems Engineering II. Springer. pags. 71-107
Aguillon-Martinez,J.E. Islas-Samperio,J.M. Martinez-Jimenez,A. Riegelhaupt,E. 2010. Bioenergia: Estado del arte y perspectivas tecnologicas en: Islas-Samperio,J. Energias Alternas: Propuesta de Investigacion y Desarrollo Tecnologico para Mexico. Mexico. Academia Mexicana de las Ciencias. pags. 43-51
Escalante,A. Martinez,A. Rivera,M. Gosset,G. 2009. Section 1 en: Smolke,C.D. Metabolic Pathway Engineering Handbook. CRC Press. pags. 10-20
Martinez-Jimenez,A. Gosset-Lagarda,G. 2008. Ingeniería metabólica de bacterias, cap 32 en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario. Mexico, D.F.. UNAM. pags. 373-384
Chavez-Bejar,M. Martinez,A. Bolivar,F. Gosset,G. 2005. Metabolic pathway engineering for microbial production of aromatic amino acids en: Moham,R.M. Research Advances in Food Science. Kerala. Global Research network. pags. 11-20
Velasco,D. Martinez,A. Galindo,E. 1994. Hydrodynamics of industrial fermentations: rheology and power draw in rifamycin production en: Penney.R. Industrial Mixing Technology: Chemical and Biological Applications. AIChE Symp. Ser. 299, Vol. 90. pags. 157-165
Velasco,D. Martinez,A. Torres,L.G. Galindo,E. 1993. Rheology and dual impeller mixing of an industrial fermentation broth containing Micromonospora purpurea en: Proceedings of the 3rd International Conference on Bioreactors & Bioprocess Fluid Dynamics. Cambridge, U.K. BHR Group Limited. pags. 101-119
Otras Publicaciones Martinez-Jimenez,A. Alvarez-Vargas,J.R. Martinez-Rodriguez,M.A.
2014. Volver al Futuro: Bioenergía, Biocombustibles y Biotecnología Revista Digital Universitaria, 15, art 60.
Trujillo-Martinez,B. Rodriguez-Alegria,M.E. Martinez,A.
2012. Bioethanol: Challenges for implementation Voices of Mexico, 93, 93-107.
Sabido,A. Martinez,A. Bolivar,F. Gosset,G.
2011. Generación de un Sistema para la Integración y Expresión de Genes en el Cromosoma de Escherichia coli Biotecnologia, 15, 35-49.
Martinez-Jimenez,A.
2011. Futuras Refinerías Están Basadas en Procesos Biotecnológicos Biotecnologia, 14, 4-5.
Martinez-Jimenez,A.
2010. Transformaciones: Aceites quemados = Combustible verde: Biodiesel Gastronómica de México, 29, 3-5.
Islas-Sampeiro,J. Martinez-Jimenez,A.
2010. Bioenergia Ciencia, Revista de la Academia Mexicana de Ciencia, 61, 30-39.
Carreon-Rodriguez,O.E. Sabido-Ramos,A. Centeno-Leija,S. Leal-Reyes,L.J. Martinez-Jimenez,A. Fernandez-Sandoval,M.T.
2009. Etanol Carburante Biotecnologia, 13, 79-102.
Garibay-Hernandez,A. Vazquez-Duhalt,R. Sanchez-Saavedra,M.P. Serrano-Carreon,L. Martinez-Jimenez,A.
2009. Biodiesel a Partir de Microalgas Biotecnologia, 13, 38-61.
Rajchenberg-Ceceña,E. Rodriguez-Ruiz,J.A. Juarez-Lopez,K. Martinez-Jimenez,A. Morales-Arrieta,S.
2009. Producción Microbiológica de Butanol Biotecnologia, 13, 26-37.
Romero,S. Orencio,M. Martinez,A. Gosset,G.
2008. Compuestos aromáticos e ingeniería metabólica en bacterias Ciencia y desarrollo, 34, 8-13.
Martinez,A. Rodriguez,M.E. Lopez-Munguia,A. Gosset,G.
2006. ¿Etanol carburante a base de bagazo de caña? Claridades Agropecuarias, 155, 22-25.
Huerta-Beristain,G. Utrilla,J. Hernandez-Chavez,G. Bolivar,F. Martinez,A.
2005. Ingenieria metabolica para incrementar el flux y rendimientos de etanol en Escherischia coli etanologenica Revista Mexicana de Ingenieria Quimica, 4, 25-36.
Escalante-Lozada,A. Gosset-Lagarda,G. Martinez-Jimenez,A. Bolivar-Zapata,F.
2004. Soil bacterial diversity: Microbial culture-independent methods of study and biotechnological implications Agrociencia, 38, 583-592.
Martinez,A. Bolivar,F. Gosset,G.
2002. Biotecnologia energetica sustentable: etanol carburante para el transporte Revista Universidad de Mexico, 617, .
Patentes José Manuel Camacho Zaragoza, Georgina Teresa Hernández Chávez, Fabián Moreno Avitia, René Ramírez Iñiguez, Alfredo Martínez Jiménez , Francisco Bolívar Zapata, Guillermo Gosset Lagarda 2017 Cepas de Escherichia coli modificadas por ingeniería de vías metabólicas para la biosíntesis de resveratrol y su uso en un nuevo proceso de co-cultivo.UNAM México. (en trámite)
Alfredo Martínez Jiménez, Guillermo Gosset Lagarda, Luz María Martínez Mejía, Georgina Teresa Hernández Chávez, Mauricio García Benítez 2016 Cepas de Escherichia coli modificadas por ingeniería metabólica para la producción de (R)-3-hidroxibutirato.UNAM México. (en trámite)
A. Martínez J. G. Gosset L. G. T. Hernández Ch. G. Huerta B. B. Trujillo y M., J. Utrilla C. 2013 Strains of Escherichia coli modified by metabolic engineering to produce chemical compounds from hydrolyzed lignocellulose, pentoses, hexoses or other carbon sources.UNAM EUA 8563283, México No. 31474 y 3127021.
Ponce Laura Grecia , Martínez Mejía Luz María , Ramírez Reivich Octavio Tonatiuh , Martínez Jiménez Alfredo , Bolívar Zapata Francisco Gonzalo , Gosset Lagarda Guillermo . 2013 Cepas de Escherichia coli con alta capacidad para la producción de plásmidos y su uso en la producción de vacunas de ADN.UNAM México. (en trámite)
Guillermo Gosset Lagarda , Alfredo Martínez Jiménez , Francisco Gonzalo Bolívar Zapata , Ana Joyce Muñoz Arellano, Georgina Teresa Hernández Chávez y Ramón de Anda Herrera 2011 Cepas de Escherichia coli modificadas para producir 3,4-hidroxi-L-fenilalanina (L-Dopa).UNAM México. (en trámite)
José Utrilla Carreri, Luz María Martínez Mejía , Guillermo Gosset Lagarda , y Alfredo Martínez Jiménez 2011 Nuevos transportadores de xilosa y sus aplicaciones. UNAM México No. 340987.
G. Gosset, A. Martínez, F. G. Bolívar, V. H. Lagunas, N. Cabrera, J. G. Dávila, V. M. González y V. P. Bustos 2004 Producción de melaninas en microorganismos recombinantes.UNAM México. (en trámite)
F. G. Bolívar Z. G. Gosset L. R. de Anda R. Quintero R. A. Martínez F. Valle N. Flores M. 1994 Proceso fermentativo para obtener proteínas híbridas a partir de cepas de Escherichia coli .UNAM México.
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