. Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. José Luis Puente García

Dr. José Luis Puente García

Líder Académico »» Grupo
Investigador
Tutor de Maestría y Doctorado
Nivel III del SNI
Departamento de Microbiología Molecular

Líneas de investigación

email: puente @ibt.unam.mx
Teléfonos
Oficina +52 (777) 329-1621
desde la CDMX 562-27621
red UNAM 27621
+52 (777) 311-4900 ext 209

Laboratorio +52 (777) 329-1627
desde la CDMX 562-27627
red UNAM 27627
+52 (777) 311-4900 ext 209

- Licenciatura: Biología, Fac. de Ciencias-UNAM (1987)
- Maestría: en Biotecnología, CEINGEBI-UNAM (1988)
- Doctorado: en Biotecnología, CEINGEBI-UNAM (1991)
- Mencion honorífica en examen de Maestría (1988)
- Mencion honorífica en examen de Doctorado (1991).
- Medalla "Gabino Barreda", Maestría (1988).
- Medalla "Gabino Barreda", Doctorado (1991).
- Beca para realizar estudios Posdoctorales en la Universidad de Stanford, CA, EUA, del Centro Internacional John E. Fogarty, NIH, USA (1992-1994)
- Estancia de Investigación: Estancia Sabática en la Universidad de British Columbia, Vancouver, Canadá (1998-1999 y 2004-2005)

Miembro de la Academia de Ciencias de Morelos (2002)
Premio de la Academia Mexicana de Ciencias en el área de Ciencias Naturales (2001)
Distinción Universidad Nacional para Jóvenes Académicos en el área de Investigación en Ciencias Naturales UNAM (2001)
Howard Hughes Medical Institute International Research Scholar 2000-2005 (2000)

Estudiantes

Paola Guadalupe Vázquez

Biol. Jordan Euler Bernaldo

M.C. Alvaro Damian Morales

Lic. Karla Fernanda Ramírez

M.C. Maria Ines Isidro

Sara Berenice Martínez "Caracterización del mecanismo molecular por el que GrlR regula negativamente los genes de la isla LEE de EPEC"

Biol. Carmen Adriana Contreras

Lic. Fabiola González

M.C. Emma Aurora Cruz

M.C. Isela Serrano

M.C Abraham Medrano

M.C. Stephanie Ortiz

Publicaciones recientes

Silva,C. Calva,E. Fernandez-Mora,M. Puente,J.L. Vinuesa,P. 2019. Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype PLoS ONE, 14, e0223975.

Montero,D.A. Canto,F.D. Velasco,J. Colello,R. Padola,N.L. Salazar,J.C. Martin,C.S. Onate,A. Blanco,J. Rasko,D.A. Contreras,C. Puente,J.L. Scheutz,F. Franz,E. Vidal,R.M. 2019. Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains Emerging Microbes and Infection, 8, 486-502.

Cornejo-Granados,F. Calderon de la Barca AM Torres,N. Martinez-Romero,E. Torres,J. Lopez-Vidal,Y. Soberon,X. Partida-Martinez,L.P. Pinto-Cardoso,S. Alcaraz,L.D. Pardo-Lopez,L. Canizales-Quinteros,S. Puente,J.L. Ochoa-Leyva,A. 2019. Microbiome-MX 2018: Microbiota and Microbiome opportunities in Mexico, a megadiverse country Research in Microbiology, 170, 235-241.

Giner-Lamia,J. Vinuesa,P. Betancor,L. Silva,C. Bisio,J. Soleto,L. Chabalgoity,J.A. Puente,J.L. Garcia-Del Portillo F. 2019. Genome analysis of Salmonella enterica subsp. diarizonae isolates from invasive human infections reveals enrichment of virulence-related functions in lineage ST1256 BMC Genomics, 20, 99 [correction 21(1):373].

Silva,C. Betancor,L. Garcia,C. Astocondor,L. Hinostroza,N. Bisio,J. Rivera,J. Perezgasga,L. Perez,E., V Yim,L. Jacobs,J. Garcia-Del Portillo F. Chabalgoity,J.A. Puente,J.L. 2017. Characterization of Salmonella enterica isolates causing bacteremia in Lima, Peru, using multiple typing methods PLoS ONE, 12, e0189946.

Silva,C. Zavala-Alvarado,C. Puente,J.L. 2017. Self-Conjugation of the Enteropathogenic Escherichia coli Adherence Factor Plasmid of Four Typical EPEC Isolates BioMed Research International, 2017, 6325736.

Quinones-Pena,M.A. Tavizon,G. Puente,J.L. Martinez-Anaya,C. Hernandez-Chinas,U. Eslava,C.A. 2017. Effects of static magnetic fields on the enteropathogenic Escherichia coli Bioelectromagnetics, 38, 570-578.

Iriarte,A. Giner-Lamia,J. Silva,C. Betancor,L. Astocondor,L. Cestero,J.J. Ochoa,T. Garcia,C. Puente,J.L. Chabalgoity,J.A. Garcia-Del Portillo F. 2017. Draft Genome Sequence of Salmonella enterica subsp. enterica Serovar Infantis Strain SPE101, Isolated from a Chronic Human Infection Genome Announcements, 5, .

Montero,D.A. Velasco,J. Del,C.F. Puente,J.L. Padola,N.L. Rasko,D.A. Farfan,M. Salazar,J.C. Vidal,R. 2017. Locus of Adhesion and Autoaggregation (LAA), a pathogenicity island present in emerging Shiga Toxin-producing Escherichia coli strains Scientific Reports, 7, 7011.

Silva,C. Puente,J.L. Calva,E. 2017. Salmonella virulence plasmid: pathogenesis and ecology Pathogens and Disease, 75, ftx070.

Puente,J.L. Calva,E. 2017. Perspective: The One Health Concept Pathogens and Disease, 75, ftx062.

Sakamoto,K. Kim,Y.G. Hara,H. Kamada,N. Caballero-Flores,G. Tolosano,E. Soares,M.P. Puente,J.L. Inohara,N. Nunez,G. 2017. IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections Science Immunology, 2, eaai8371.

Soto,E. Espinosa,N. Diaz-Guerrero,M. Gaytan,M.O. Puente,J.L. Gonzalez-Pedrajo,B. 2017. Functional Characterization of EscK (Orf4), a Sorting Platform Component of the Enteropathogenic Escherichia coli Injectisome Journal of Bacteriology, 199, e00538-16.

Colgan,A.M. Kroger,C. Diard,M. Hardt,W.D. Puente,J.L. Sivasankaran,S.K. Hokamp,K. Hinton,J.C. 2016. The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium PLoS Genetics, 12, e1006258.

Vinuesa,P. Puente,J.L. Calva,E. Zaidi,M.B. Silva,C. 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain SO3 (Sequence Type 302) Isolated from a Baby with Meningitis in Mexico Genome Announcements, 4, .

Silva,C. Calva,E. Puente,J.L. Zaidi,M.B. Vinuesa,P. 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain YU15 (Sequence Type 19) Harboring the Salmonella Genomic Island 1 and Virulence Plasmid pSTV Genome Announcements, 4, .

Silva,C. Calva,E. Puente,J.L. Zaidi,M.B. Vinuesa,P. 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain SO2 (Sequence Type 302) Isolated from an Asymptomatic Child in Mexico Genome Announcements, 4, .

Silva,C. Calva,E. Calva,J.J. Wiesner,M. Fernandez-Mora,M. Puente,J.L. Vinuesa,P. 2015. Complete Genome Sequence of a Human-Invasive Salmonella enterica Serovar Typhimurium Strain of the Emerging Sequence Type 213 Harboring a Multidrug Resistance IncA/C Plasmid and a blaCMY-2-Carrying IncF Plasmid Genome Announcements, 3, .

Kamada,N. Sakamoto,K. Seo,S.U. Zeng,M.Y. Kim,Y.G. Cascalho,M. Vallance,B.A. Puente,J.L. Nunez,G. 2015. Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination Cell Host and Microbe, 17, 617-627.

Caballero-Flores,G.G. Croxen,M.A. Martinez-Santos,V.I. Finlay,B.B. Puente,J.L. 2015. Identification and regulation of a novel Citrobacter rodentium gut colonization fimbria (Gcf) Journal of Bacteriology, 197, 1478-1491.

Gutierrez-Huante,M. Martinez,H. Bustamante,V.H. Puente,J.L. Sanchez,J. 2015. Bicarbonate enhances the in vitro antibiotic activity of kanamycin in Escherichia coli Letters in Applied Microbiology, 60, 440-446.

Saldana,Z. De la Cruz,M.A. Carrillo-Casas,E.M. Duran,L. Zhang,Y. Hernandez-Castro,R. Puente,J.L. Daaka,Y. Giron,J.A. 2014. Production of the Escherichia coli Common Pilus by Uropathogenic E. coli Is Associated with Adherence to HeLa and HTB-4 Cells and Invasion of Mouse Bladder Urothelium PLoS ONE, 9, e101200.

Arenas-Hernandez,M.M. Rojas-Lopez,M. Medrano-Lopez,A. Nunez-Reza,K.J. Puente,J.L. Martinez-Laguna,Y. Torres,A.G. 2014. Environmental regulation of the long polar fimbriae 2 of enterohemorrhagic Escherichia coli O157:H7 Fems Microbiology Letters, 357, 105-114.

Martinez,L.C. Martinez-Flores,I. Salgado,H. Fernandez-Mora,M. Medina-Rivera,A. Puente,J.L. Collado-Vides,J. Bustamante,V.H. 2014. In Silico Identification and Experimental Characterization of Regulatory Elements Controlling the Expression of the Salmonella csrB/C Genes Journal of Bacteriology, 196, 325-336.

Hernandez-Tamayo,R. Sohlenkamp,C. Puente,J.L. Brom,S. Romero,D. 2013. Characterization of IntA, a bidirectional site-specific recombinase required for conjugative transfer of the symbiotic plasmid of Rhizobium etli CFN42 Journal of Bacteriology, 195, 4668-4677.

Ibarra,J.A. Garcia-Zacarias,C.M. Lara-Ochoa,C. Carabarin-Lima,A. Tecpanecatl-Xihuitl,J.S. Perez-Rueda,E. Martinez-Laguna,Y. Puente,J.L. 2013. Further Characterization of Functional Domains of PerA, Role of Amino and Carboxy Terminal Domains in DNA Binding PLoS ONE, 8, e56977.

Castaneda-Ramirez,A. Puente,J.L. Gonzalez-Noriega,A. Verdugo-Rodriguez,A. 2012. Silencing of VAMP3 expression does not affect Brucella melitensis infection in mouse macrophages Virulence, 3, 434-439.

Garcia-Angulo,V.A. Martinez-Santos,V.I. Villasenor,T. Santana,F.J. Huerta-Saquero,A. Martinez,L.C. Jimenez,R. Lara-Ochoa,C. Tellez-Sosa,J. Bustamante,V.H. Puente,J.L. 2012. A Distinct Regulatory Sequence Is Essential for the Expression of a Subset of nle Genes in Attaching and Effacing Escherichia coli Journal of Bacteriology, 194, 5589-5603.

Martinez-Santos,V.I. Medrano-Lopez,A. Saldana,Z. Giron,J.A. Puente,J.L. 2012. Transcriptional regulation of the ecp operon by EcpR, IHF and H-NS in attaching and effacing Escherichia coli Journal of Bacteriology, 194, 5020-5033.

Kamada,N. Kim,Y.G. Sham,H.P. Vallance,B.A. Puente,J.L. Martens,E.C. Nunez,G. 2012. Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota Science, 336, 1325-1329.

Garnett,J.A. Martinez-Santos,V.I. Saldana,Z. Pape,T. Hawthorne,W. Chan,J. Simpson,P.J. Cota,E. Puente,J.L. Giron,J.A. Matthews,S. 2012. Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus Proceedings of the National Academy of Sciences of the United States of America, 109, 3950-3955.

Bustamante,V.H. Villalba,M.I. Garcia-Angulo,V.A. Vazquez,A. Martinez,L.C. Jimenez,R. Puente,J.L. 2011. PerC and GrlA independently regulate Ler expression in enteropathogenic Escherichia coli Molecular Microbiology, 82, 398-415.

Saldana,Z. Sanchez,E. Xicohtencatl-Cortes,J. Puente,J.L. Giron,J.A. 2011. Surface structures involved in plant stomata and leaf colonization by shiga-toxigenic Escherichia coli o157:h7 Frontiers in Microbiology, 2, 119.

Martinez,L.C. Yakhnin,H. Camacho,M.I. Georgellis,D. Babitzke,P. Puente,J.L. Bustamante,V.H. 2011. Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI-1 and SPI-2 virulence regulons through HilD Molecular Microbiology, 80, 1637-1656.

Rojas-Lopez,M. Arenas-Hernandez,M.M. Medrano-Lopez,A. Martinez de la Pena CF Puente,J.L. Martinez-Laguna,Y. Torres,A.G. 2011. Regulatory control of Escherichia coli O157:H7 lpf1 operon by H-NS and Ler Journal of Bacteriology, 193, 1622-1632.

Xicohtencatl-Cortes,J. Saldana,Z. Deng,W. Castaneda,E. Freer,E. Tarr,P.I. Finlay,B.B. Puente,J.L. Giron,J.A. 2010. Bacterial macroscopic rope-like fibers with cytopathic and adhesive properties Journal of Biological Chemistry, 285, 32336-32342.

Jimenez,R. Cruz-Migoni,S.B. Huerta-Saquero,A. Bustamante,V.H. Puente,J.L. 2010. Molecular characterization of GrlA, a specific positive regulator of ler expression in enteropathogenic Escherichia coli Journal of Bacteriology, 192, 4627-4642.

Deng,W. de Hoog,C.L. Yu,H.B. Li,Y. Croxen,M.A. Thomas,N.A. Puente,J.L. Foster,L.J. Finlay,B.B. 2010. A comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium Journal of Biological Chemistry, 285, 6790-6800.

Gao,X. Wan,F. Mateo,K. Callegari,E. Wang,D. Deng,W. Puente,J. Li,F. Chaussee,M.S. Finlay,B.B. Lenardo,M.J. Hardwidge,P.R. 2009. Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function PLoS Pathogens, 5, e1000708.

Saldana,Z. Erdem,A.L. Schuller,S. Okeke,I.N. Lucas,M. Sivananthan,A. Phillips,A.D. Kaper,J.B. Puente,J.L. Giron,J.A. 2009. The Escherichia coli common pilus and the bundle-forming pilus act in concert during the formation of localized adherence by enteropathogenic E. coli Journal of Bacteriology, 191, 3451-3461.

Saldana,Z. Xicohtencatl-Cortes,J. Avelino,F. Phillips,A.D. Kaper,J.B. Puente,J.L. Giron,J.A. 2009. Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli Environmental Microbiology, 11, 992-1006.

Xicohtencatl-Cortes,J. Monteiro-Neto,V. Saldana,Z. Ledesma,M.A. Puente,J.L. Giron,J.A. 2009. The type 4 pili of enterohemorrhagic Escherichia coli O157:H7 are multi-purpose structures with pathogenic attributes Journal of Bacteriology, 191, 411-421.

Bustamante,V.H. Martinez,L.C. Santana,F.J. Knodler,L.A. Steele-Mortimer,O. Puente,J.L. 2008. HilD-mediated transcriptional cross-talk between SPI-1 and SPI-2 Proceedings of the National Academy of Sciences of the United States of America, 105, 14591-14596.

Echtenkamp,F. Deng,W. Wickham,M.E. Vazquez,A. Puente,J.L. Thanabalasuriar,A. Gruenheid,S. Finlay,B.B. Hardwidge,P.R. 2008. Characterization of the NleF effector protein from attaching and effacing bacterial pathogens Fems Microbiology Letters, 281, 98-107.

Garcia-Angulo,V.A. Deng,W. Thomas,N.A. Finlay,B.B. Puente,J.L. 2008. Regulation of expression and secretion of NleH, a new non-LEE-encoded effector in Citrobacter rodentium Journal of Bacteriology, 190, 2388-2399.

Hernandez-Castro,R. Verdugo-Rodriguez,A. Puente,J.L. Suarez-Guemes,F. 2008. The BMEI0216 gene of Brucella melitensis is required for internalization in HeLa cells Microbial Pathogenesis, 44, 28-33.

Ibarra,J.A. Perez-Rueda,E. Segovia,L. Puente,J.L. 2008. The DNA-binding domain as a functional indicator: the case of the AraC/XylS family of transcription factors Genetica, 133, 65-76.

Xicohtencatl-Cortes,J. Monteiro-Neto,V. Ledesma,M.A. Jordan,D.M. Francetic,O. Kaper,J.B. Puente,J.L. Giron,J.A. 2007. Intestinal adherence associated with type IV pili of enterohemorrhagic Escherichia coli O157:H7 Journal of Clinical Investigation, 117, 3519-vol 3529 (Correction vol 118 no y2 p 820).

Duong,N. Osborne,S. Bustamante,V.H. Tomljenovic,A.M. Puente,J.L. Coombes,B.K. 2007. Thermosensing coordinates a cis-regulatory module for transcriptional activation of the intracellular virulence system in salmonella enterica serovar typhimurium Journal of Biological Chemistry, 282, 34077-84.

Trevino-Quintanilla,L.G. Escalante,A. Caro,A.D. Martinez,A.(error para richar) Puente,J.L. Bolivar,F. Gosset,G. 2007. The Phosphotransferase System-Dependent Sucrose Utilization Regulon in Enteropathogenic Escherichia coli Strains Is Located in a Variable Chromosomal Region Containing iap Sequences Journal of Molecular Microbiology and Biotechnology, 13, 117-125.

Thomas,N.A. Deng,W. Baker,N.T. Puente,J.L. Finlay,B.B. 2007. Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli Journal of Biological Chemistry, 282, 29634-45.

Rendon,M.A. Saldana,Z. Erdem,A.L. Monteiro-Neto,V. Vazquez,A. Kaper,J.B. Puente,J.L. Giron,J.A. 2007. Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization Proceedings of the National Academy of Sciences of the United States of America, 104, 10637-10642.

Reyes-Leon,A. Atherton,J.C. Argent,R.H. Puente,J.L. Torres,J. 2007. Heterogeneity in the activity of Mexican Helicobacter pylori strains on gastric epithelial cells and its association with diversity in the cagA gene Infection and Immunity, 75, 3445-3454.

Wickham,M.E. Lupp,C. Vazquez,A. Mascarenhas,M. Coburn,B. Coombes,B.K. Karmali,M.A. Puente,J.L. Deng,W. Finlay,B.B. 2007. Citrobacter rodentium virulence in mice associates with bacterial load and the type III effector NleE Microbes and Infection, 9, 400-407.

Wickham,M.E. Lupp,C. Mascarenhas,M. Vazquez,A. Coombes,B.K. Brown,N.F. Coburn,B.A. Deng,W. Puente,J.L. Karmali,M.A. Finlay,B.B. 2006. Bacterial Genetic Determinants of Non-O157 STEC Outbreaks and Hemolytic-Uremic Syndrome after Infection Journal of Infectious Diseases, 194, 819-827.

Rodriguez-Morales,O. Fernandez-Mora,M. Hernandez-Lucas,I. Vazquez,A. Puente,J.L. Calva,E. 2006. Salmonella enterica Serovar Typhimurium ompS1 and ompS2 Mutants Are Attenuated for Virulence in Mice Infection and Immunity, 74, 1398-1402.

Secundino,I. Lopez-Macias,C. Cervantes-Barragan,L. Gil-Cruz,C. Rios-Sarabia,N. Pastelin-Palacios,R. Villasis-Keever,M.A. Becker,I. Puente,J.L. Calva,E. Isibasi,A. 2006. Salmonella porins induce a sustained, lifelong specific bactericidal antibody memory response Immunology, 117, 59-70.

Barba,J. Bustamante,V.H. Flores-Valdez,M.A. Deng,W. Finlay,B.B. Puente,J.L. 2005. A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlA Journal of Bacteriology, 187, 7918-7930.

Rosario,C.C. Puente,J.L. Verdugo-Rodriguez,A. Anderson,R.C. Eslava,C.C. 2005. Phenotypic characterization of ipaH plus Escherichia coli strains associated with yolk sac infection Avian Diseases, 49, 409-417.

Gauthier,A. Robertson,M.L. Lowden,M. Ibarra,J.A. Puente,J.L. Finlay,B.B. 2005. Transcriptional Inhibitor of Virulence Factors in Enteropathogenic Escherichia coli Antimicrobial Agents and Chemotherapy, 49, 4101-4109.

Thomas,N.A. Deng,W. Puente,J.L. Frey,E.A. Yip,C.K. Strynadka,N.C. Finlay,B.B. 2005. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli Molecular Microbiology, 57, 1762-1779.

Deng,W. Li,Y. Hardwidge,P.R. Frey,E.A. Pfuetzner,R.A. Lee,S. Gruenheid,S. Strynadka,N.C. Puente,J.L. Finlay,B.B. 2005. Regulation of Type III Secretion Hierarchy of Translocators and Effectors in Attaching and Effacing Bacterial Pathogens Infection and Immunity, 73, 2135-2146.

Fernandez-Mora,M. Puente,J.L. Calva,E. 2004. OmpR and LeuO Positively Regulate the Salmonella enterica Serovar Typhi ompS2 Porin Gene Journal of Bacteriology, 186, 2909-2920.

Deng,W. Puente,J.L. Gruenheid,S. Li,Y. Vallance,B.A. Vazquez,A. Barba,J. Ibarra,J.A. O'Donnell,P. Metalnikov,P. Ashman,K. Lee,S. Goode,D. Pawson,T. Finlay,B.B. 2004. Dissecting virulence: Systematic and functional analyses of a pathogenicity island Proceedings of the National Academy of Sciences of the United States of America, 101, 3597-3602.

Flores-Valdez,M.A. Puente,J.L. Calva,E. 2003. Negative Osmoregulation of the Salmonella ompS1 Porin Gene Independently of OmpR in an hns Background Journal of Bacteriology, 185, 6497-6506.

Ibarra,J.A. Villalba,M.I. Puente,J.L. 2003. Identification of the DNA Binding Sites of PerA, the Transcriptional Activator of the bfp and per Operons in Enteropathogenic Escherichia coli Journal of Bacteriology, 185, 2835-2847.

Gauthier,A. Puente,J.L. Finlay,B.B. 2003. Secretin of the Enteropathogenic Escherichia coli Type III Secretion System Requires Components of the Type III Apparatus for Assembly and Localization Infection and Immunity, 71, 3310-3319.

Deng,W. Vallance,B.A. Li,Y. Puente,J.L. Finlay,B.B. 2003. Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice Molecular Microbiology, 48, 95-115.

Zaharik,M.L. Vallance,B.A. Puente,J.L. Gros,P. Finlay,B.B. 2002. Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes Proceedings of the National Academy of Sciences of the United States of America, 99, 15705-15710.

DeVinney,R. Puente,J.L. Gauthier,A. Goosney,D. Finlay,B.B. 2001. Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation Molecular Microbiology, 41, 1445-1458.

Sanchez-SanMartin,C. Bustamante,V.H. Calva,E. Puente,J.L. 2001. Transcriptional regulation of the orf19 gene and the tir-cesT-eae operon of enteropathogenic Escherichia coli Journal of Bacteriology, 183, 2823-2833.

Bustamante,V.H. Santana,F.J. Calva,E. Puente,J.L. 2001. Transcriptional regulation of type III secretion genes in enteropathogenic Escherichia coli: Ler antagonizes H-NS-dependent repression Molecular Microbiology, 39, 664-678.

Oropeza,R. Sampieri,C.L. Puente,J.L. Calva,E. 1999. Negative and positive regulation of the non-osmoregulated ompS1 porin gene in Salmonella typhi: a novel regulatory mechanism that involves OmpR Molecular Microbiology, 32, 243-252.

Martinez-Flores,I. Cano,R. Bustamante,V.H. Calva,E. Puente,J.L. 1999. The ompB operon partially determines differential expression of OmpC in Salmonella typhi and Escherichia coli Journal of Bacteriology, 181, 556-562.

Martinez-Laguna,Y. Calva,E. Puente,J.L. 1999. Autoactivation and environmental regulation of bfpT expression, the gene coding for the transcriptional activator of bfpA in enteropathogenic Escherichia coli Molecular Microbiology, 33, 153-166.

Abe,A. de Grado,M. Pfuetzner,R.A. Sanchez-SanMartin,C. DeVinney,R. Puente,J.L. Strynadka,N.C. Finlay,B.B. 1999. Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion Molecular Microbiology, 33, 1162-1175.

Martinez-Flores,I. Oropeza,R. Cano,R. Sampieri,C.L. Puente,J.L. Calva,E. 1998. Novel porin genes and modes of porin regulation in salmonella typhi Medical Journal of Indonesia, 7, 25-29.

Bustamante,V.H. Calva,E. Puente,J.L. 1998. Analysis of cis-acting elements required for bfpA expression in enteropathogenic Escherichia coli Journal of Bacteriology, 180, 3013-3016.

Edwards,R.A. Puente,J.L. 1998. Fimbrial expression in enteric bacteria: a critical step in intestinal pathogenesis Trends In Microbiology, 6, 282-287.

Calva,E. Ordonez,L.G. Fernandez-Mora,M. Santana,F.J. Bobadilla,M. Puente,J.L. 1997. Distinctive IS200 insertion between gyrA and rcsC genes in Salmonella typhi Journal of Clinical Microbiology, 35, 3048-3053.

Schoolnik,G.K. Tobe,T. Puente,J.L. 1997. The per regulator of enteropathogenic Escherichia coli Molecular Microbiology, 23, 180-181.

Puente,J.L. Bieber,D. Ramer,S.W. Murray,W. Schoolnik,G.K. 1996. The bundle-forming pili of enteropathogenic Escherichia coli: transcriptional regulation by environmental signals Molecular Microbiology, 20, 87-100 * .

Sohel,I. Puente,J.L. Ramer,S.W. Bieber,D. Wu,C.Y. Schoolnik,G.K. 1996. Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis Journal of Bacteriology, 178, 2613-2628.

Tobe,T. Schoolnik,G.K. Sohel,I. Bustamante,V.H. Puente,J.L. 1996. Cloning and characterization of bfpTVW, genes required for the transcriptional activation of bfpA in enteropathogenic Escherichia coli Molecular Microbiology, 21, 963-975.

Puente,J.L. Juarez,D. Bobadilla,M. Arias,C.F. Calva,E. 1995. The Salmonella ompC gene: structure and use as a carrier for heterologous sequences Gene, 156, 1-9.

Fernandez-Mora,M. Oropeza,R. Puente,J.L. Calva,E. 1995. Isolation and characterization of ompS1, a novel Salmonella typhi outer membrane protein-encoding gene Gene, 158, 67-72.

Bustamante,V.H. Puente,J.L. Sanchez-Lopez,F. Bobadilla,M. Calva,E. 1995. Identification of Campylobacter jejuni and C. coli using the rpoB gene and a cryptic DNA fragment from C. jejuni Gene, 165, 1-8.

Martinez-Flores,I. Bustamante,V.H. Puente,J.L. Calva,E. 1995. CLONING AND CHARACTERIZATION OF THE SALMONELLA-TYPHI OMPR AND ENVZ GENES.Asia-Pacific Journal Of Molecular Biology And Biotechnology, 3, 135-144.

Merino,E. Balbas,P. Puente,J.L. Bolivar,F. 1994. Antisense overlapping open reading frames in genes from bacteria to humans Nucleic Acids Research, 22, 1903-1908.

Sohel,I. Puente,J.L. Murray,W.J. Vuopio-Varkila,J. Schoolnik,G.K. 1993. Cloning and characterization of the bundle-forming pilin gene of enteropathogenic Escherichia coli and its distribution in Salmonella serotypes Molecular Microbiology, 7, 563-575 * .

Verdugo-Rodriguez,A. Lopez-Vidal,Y. Puente,J.L. Ruiz-Palacios,G.M. Calva,E. 1993. Early diagnosis of typhoid fever by an enzyme immunoassay using Salmonella typhi outer membrane protein preparations European Journal of Clinical Microbiology & Infectious Diseases, 12, 248-254.

Puente,J.L. Verdugo-Rodriguez,A. Calva,E. 1991. Expression of Salmonella typhi and Escherichia coli OmpC is influenced differently by medium osmolarity; dependence on Escherichia coli OmpR Molecular Microbiology, 5, 1205-1210.

Puente,J.L. Alvarez-Scherer,V. Gosset,G. Calva,E. 1989. Comparative analysis of the Salmonella typhi and Escherichia coli ompC genes Gene, 83, 197-206.

Calva,E. Puente,J.L. Calva,J.J. 1988. Research opportunities in typhoid fever: epidemiology and molecular biology Bioessays, 9, 173-177.

Puente,J.L. Flores,V. Fernandez,M. Fuchs,Y. Calva,E. 1987. Isolation of an ompC-like outer membrane protein gene from Salmonella typhi Gene, 61, 75-83.

Puente-Garcia,J.L. 2014. El lado bueno de una bacteria llamada Escherichia Coli en: Rebolledo,F. Un Mundo de Bacterias. UNAM, Campus Morelos. pags. 63-64

Medrano-Lopez,A. Huerta,A. Puente,J.L. 2012. Escherichia coli enteropatógena, mecanismos de patogenicidad en: Martinez,Y. Modelos de Patogénesis de las Enfermedades Infecciosas II. Benemérita Universidad Autónoma de Puebla. pags. 1-21

Puente,J.L. 2003. El genoma de Escherichia coli y otras enterobacterias patógenas en: *bolivar Fronteras de la Biología en los Inicios del Siglo XXI Módulo I,. Mexico,D.F.. El Colegio Nacional. pags. 73-92

Bolivar,F. Lopez,S. Arias,C.F. Puente,J.L. Palacios,R. Davila,G. Flores,M. Gonzalez,A. de Luna,A. Anaya,V. Covarrubias,A. Cantu,J.M. Garcia,J.E. Collado,J. Medrano,A. 2003. Fronteras de la Biología en los Inicios del Siglo XXI: Genómica, Proteómica y Bioinformática. Mexico, D.F.: El Colegio Nacional.

Puente,J.L. Finlay,B.B. 2001. Pathogenic Escherichia coli en: Groisman,E. Principles of Bacterial Pathogenesis. San Diego. Academic Press. pags. 387-456

Calva,E. Fernandez-Mora,M. Martinez-Flores,I. Oropeza,R. Puente,J.L. 2001. Are there more cellular factors involved in the control of porin synthesis in Salmonella typhi? en: Chu,C. Typhoid fever and other salmonellosis /International Symposium on Typhoid Fever and Other Salmonellosis. Taipei, Republic of China. Jeou-Chou Book Co. pags. 165-178

Otras Publicaciones

Puente,J.L. Calva,E. 2017. El cocoliztli: armas biológicas involuntarias durante la conquista de México Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 10, 29-32.

Caballero-Flores,G.G. Puente-Garcia,J.L. 2015. Fimbrias: estructuras bacterianas que promueven la colonización intestinal por bacterias patógenas Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 3, 9-10.

Calva,E. Puente,J.L. 1995. The genetics of Salmonellae and vaccine development..Southeast Asian Journal of Tropical Medicine and Public Health, 26, 246-250.

Calva,E. Puente,J.L. 1995. Salmonella typhi outer membrane proteins: their roles in typhoid fever.Southeast Asian Journal of Tropical Medicine and Public Health, 26, 138-144.

Patentes

W. Deng, B. Finlay, S. Gruenheid, J. L. Puente, y B. A. Vallance 2006 Bacterial virulence factors and uses thereof.UNAM -Universidad de la Columbia Británica, Canadá PCT, Sudáfrica 2006/044112, Bielorrusia a2006053, India 2984/DELNP/2006, Brasil PI0415816-4, China 200480039568.9, Corea 2006-7010661, Ucrania 2006 05985, Filipinas 1-2006-501046, Noruega 20062361, Nueva Zelanda 547156, Estados Unidos 10/577,742, Australia 2004286002, Canadá 2543763, Colombia 06-52.194, Rusia 2006118803, Unión Europea 047899798.8, Japón 2006-537022, México. (en trámite)

W. Deng, B. Finlay, S. Gruenheid, J. L. Puente, y B. A. Vallance 2006 Bacterial virulence factors and uses thereof.UNAM -Universidad de la Columbia Británica, Canadá Bielorrusia a2006053, India 2984/DELNP/2006, Brasil PI0415816-4, China 200480039568.9, Corea 2006-7010661, Ucrania 2006 05985, Filipinas 1-2006-501046, Noruega 20062361, Nueva Zelanda 547156, Estados Unidos 10/577,742, Australia 2004286002, Canadá 2543763, Colombia 06-52.194, Rusia 2006118803, Unión Europea 047899798.8, Japón 2006-537022, México. (en trámite)

B. B. Finlay, J. L. Puente, W. Deng, S. Gruenheid y B. A. Vallance 2004 Bacterial virulence factors and uses thereof. .UNAM -Universidad de la Columbia Británica, Canadá PCT 2006/044112 Sudafrica. (en trámite)

B. B. Finlay, J. L. Puente, W. Deng, S. Gruenheidy y B. A. Vallance 2004 Bacterial virulence factors and uses.UNAM -Universidad de la columbia Británica, Canadá Argentina. (en trámite)

B. B. Finlay, J. L. Puente, W. Deng, S. Gruenheid y B. A. Vallance 2004 Bacterial Virulence Factors and Uses Thereof. .UNAM -Universidad de la columbia Brit·nica, Canad· PCT. (en trámite)

* Indica publicación con otra institución de adscripción